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Tissue Introduction
         &
 Epithelial Tissue

     BAKHTIARI
      DMD 1DD
Cells to Tissues
 As human body develops from single
  to multicellular, cells specialize.
 Body is interdependent system,

  malfunction of one group of cells is
  catastrophic.
 Cells specialize into types of tissues,

  then interspersed into organs.
Tissues = groups of cells that are
similar in structure and function.
    Epithelium                   Muscle
        Coverings                    Movement
        Linings of surfaces

    Connective                   Nervous
        Support                      Control
        Bone, ligaments,             Brain, nerves,
         fat                           spinal cord
Function of Epithelial Tissue
   Protection
      Skin protects from sunlight & bacteria & physical
       damage.
   Absorption
      Lining of small intestine, absorbing nutrients into
       blood
   Filtration
      Lining of Kidney tubules filtering wastes from blood
       plasma
   Secretion
      Different glands produce perspiration, oil, digestive
       enzymes and mucus
Characteristics of Epithelial Tissue
   Form continuous sheets (fit like tiles)
   Apical Surface
       All epithelial cells have a top surface that
        borders an open space  known as a lumen
   Basement Membrane
       Underside of all epithelial cells which anchors
        them to connective tissue
   Avascularity (a = without)
       Lacks blood vessels
       Nourished by connective tissue
   Regenerate & repair quickly
Classification of
    Epithelial Tissue
   Cell Shape
       Squamous  flattened like
        fish scales
       Cuboidal - cubes
       Columnar - columns
   Cell Layers
       Simple (one layer)
       Stratified (many layers)
            Named for the type of cell at
             the apical surface.
Simple Squamous Epithelium
   Structure
       Single Layer of flattened cells
   Function
       Absorption, and filtration
       Not effective protection  single layer of cells.
   Location
       Walls of capillaries, air sacs in lungs
       Form serous membranes in body cavity
Epithelialtissue 120208062655-phpapp02
Simple Cuboidal Epithelium
   Structure
       Single layer of cube shaped cells
   Function
       Secretion and transportation in glands,
        filtration in kidneys
   Location
       Glands and ducts (pancreas & salivary),
        kidney tubules, covers ovaries
Epithelialtissue 120208062655-phpapp02
Simple Columnar Epithelium
   Structure
       Elongated layer of cells with nuclei at same level
   Function
       Absorption, Protection & Secretion
       When open to body cavities  called mucous
        membranes
   Special Features
       Microvilli, bumpy extension of apical surface, increase
        surface area and absorption rate.
       Goblet cells, single cell glands, produce protective
        mucus.
   Location
       Linings of entire digestive tract
Epithelialtissue 120208062655-phpapp02
Pseudostratified Epithelium
   Structure
       Irregularly shaped cells with nuclei at different
        levels  appear stratified, but arent.
       All cells reach basement membrane
   Function
       Absorption and Secretion
       Goblet cells produce mucus
       Cilia (larger than microvilli) sweep mucus
   Location
       Respiratory Linings & Reproductive tract
Cilia



Basement
Membrane
Stratified Squamous Epithelium
   Structure
       Many layers (usually cubodial/columnar at
        bottom and squamous at top)
   Function
       Protection
       Keratin (protein) is accumulated in older cells
        near the surface  waterproofs and toughens
        skin.
   Location
       Skin (keratinized), mouth & throat
Keratin




    Stratified
Cubodial (layers
of cubodial only)
Transitional Epithelium
   Structure
       Many layers
       Very specialized  cells at base are cuboidal
        or columnar, at surface will vary.
       Change between stratified & simple as tissue
        is stretched out.
   Function
       Allows stretching (change size)
   Location
       Urinary bladder, ureters & urethra
Epithelialtissue 120208062655-phpapp02

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Epithelialtissue 120208062655-phpapp02

  • 1. Tissue Introduction & Epithelial Tissue BAKHTIARI DMD 1DD
  • 2. Cells to Tissues As human body develops from single to multicellular, cells specialize. Body is interdependent system, malfunction of one group of cells is catastrophic. Cells specialize into types of tissues, then interspersed into organs.
  • 3. Tissues = groups of cells that are similar in structure and function. Epithelium Muscle Coverings Movement Linings of surfaces Connective Nervous Support Control Bone, ligaments, Brain, nerves, fat spinal cord
  • 4. Function of Epithelial Tissue Protection Skin protects from sunlight & bacteria & physical damage. Absorption Lining of small intestine, absorbing nutrients into blood Filtration Lining of Kidney tubules filtering wastes from blood plasma Secretion Different glands produce perspiration, oil, digestive enzymes and mucus
  • 5. Characteristics of Epithelial Tissue Form continuous sheets (fit like tiles) Apical Surface All epithelial cells have a top surface that borders an open space known as a lumen Basement Membrane Underside of all epithelial cells which anchors them to connective tissue Avascularity (a = without) Lacks blood vessels Nourished by connective tissue Regenerate & repair quickly
  • 6. Classification of Epithelial Tissue Cell Shape Squamous flattened like fish scales Cuboidal - cubes Columnar - columns Cell Layers Simple (one layer) Stratified (many layers) Named for the type of cell at the apical surface.
  • 7. Simple Squamous Epithelium Structure Single Layer of flattened cells Function Absorption, and filtration Not effective protection single layer of cells. Location Walls of capillaries, air sacs in lungs Form serous membranes in body cavity
  • 9. Simple Cuboidal Epithelium Structure Single layer of cube shaped cells Function Secretion and transportation in glands, filtration in kidneys Location Glands and ducts (pancreas & salivary), kidney tubules, covers ovaries
  • 11. Simple Columnar Epithelium Structure Elongated layer of cells with nuclei at same level Function Absorption, Protection & Secretion When open to body cavities called mucous membranes Special Features Microvilli, bumpy extension of apical surface, increase surface area and absorption rate. Goblet cells, single cell glands, produce protective mucus. Location Linings of entire digestive tract
  • 13. Pseudostratified Epithelium Structure Irregularly shaped cells with nuclei at different levels appear stratified, but arent. All cells reach basement membrane Function Absorption and Secretion Goblet cells produce mucus Cilia (larger than microvilli) sweep mucus Location Respiratory Linings & Reproductive tract
  • 15. Stratified Squamous Epithelium Structure Many layers (usually cubodial/columnar at bottom and squamous at top) Function Protection Keratin (protein) is accumulated in older cells near the surface waterproofs and toughens skin. Location Skin (keratinized), mouth & throat
  • 16. Keratin Stratified Cubodial (layers of cubodial only)
  • 17. Transitional Epithelium Structure Many layers Very specialized cells at base are cuboidal or columnar, at surface will vary. Change between stratified & simple as tissue is stretched out. Function Allows stretching (change size) Location Urinary bladder, ureters & urethra