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collimator instrumentation polymer xray diffraction and their applications x-ray diffraction detector scintillation counter monochromator geiger muller tube medicine production of xrays metallurgy structure of crystals gastro intestinal gastric emptying ph partition physiochemical factor amorphism pharmaceutical factors ph disease state intestinal transit drug solubility & dissolution rate presystemic metabolism salt formation method of preperation and effect of excipients polymorphism gastro intestinalcontents age physiological factors particle size transport process drug absorption factors affecting drug absorption