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The Cell
 Cell Overview
 The Plasma Membrane
 Key Organelles
Numbers, Variety, Sizes
 50  106 Trillion cells in the body
 ~200 different kinds of cells in body
nerve, blood, muscle, liver, kidney
 Length: 2 microns  over 1 meter
Platelets = 2 microns
nerve cells = over 3 feet long
Generalized Cell
Cellular Components
 Plasma Membrane
 Nucleus
 Organelles
 Cytosol:
water, ions, nutrients, waste products
 Granules:
glycogen, melanin
The Plasma Membrane
The Fluid Mosaic Model
Phospholipid bilayer
structural support
Cholesterol
fluidity, flexibility
Proteins (many kinds)
receptors
enzymes
transporters
ion channels
specialized connections
Crossing The Plasma Membrane
Mechanisms:
 Passive
NO ATP required
 Active
ATP Required
 Simple Diffusion
(High -> Low concentration)
 Osmosis (water mvt)
 Facilitated Transport
(transporter protein)
 Active Transport
(Low -> High concentration)
 Sodium/Potassium pump
(Mvt of Larger molecules)
 Endocytosis
 Exocytosis
Key Organelles
Nucleus
Mitochondria
Ribosomes
Golgi
Endoplasmic
reticulum
Nucleus
Double plasma
membrane with
large pores
Nucleolus for
ribosome synthesis
Chromatin(DNA-
protein)
Extendedbarely
visible
Condensed--
visible
Ribosomes
Protein synthesis (translation of mRNA)
free or associated with endoplasmic reticulum
2 subunits made in nucleolus from nucleic acids and proteins
Endoplasmic Reticulum
A continuous membrane
system:
Nuclear Membrane-
Rough ER-Smooth ER
Rough ER (Ribosomes,
newly synthesized proteins)
Smooth ER (Lipid
synthesis, transport)
Mitochondria
Powerhouse of the
Cell
Site of Aerobic
respiration:
O2 used in oxidation
of glucose, fats to
produce ATP
Vary in # and size
within cells
Double membrane
Golgi Apparatus
Packaging & Transport

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