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psychiatry sleep disorders sleep stress limbic system limbic system disorders substance use substance abuse addiction delirium organic psychosis brief psychotic disorder atpd schizophrenia biology of memory memory alzhiemers recent advances in alzhiemers 2nd generation antipsychotics history of antipsychotics antipsychotics mechanism of action of antipsychotics atypical antipsychotics course of schizophrenia schizophrenia famous studies prognosis of schizophrenia outcome of schizophrenia course and outcome of schizophrenia in india