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kidney transplantation outcome rejection survival review histology kidney transplantation biomarkers personalized medicine prediction immunosuppressive agents liver heart endpoint lung living donor biopsy abo microarray reclassification chronic function non-invasive machine perfusion xenotransplantation combined renal chimerism dialysis intestinal onderzoeken pretranslantbilan leuven uz leuven evaluatie pretransplant protocols blood group living expression gene systems medicine eurotransplant resistive index antibodies banff barcelona stockholm karolinska fibrosis scoring system allocation discard calcineurin nephrotoxicity randomized trials course precision medicine markers monitoring conference inflammation pigs tissue engineering islet epitope matching pancreas 3d printing history study infections contra-indications cancer indications desensitisation plasmapheresis nephrology immunoadsorption hla therapy