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namrata chhabra biochemistry for medics our biochemistry namrata's biochemistry biochemistry glycogen case studies enzymology dna active site glycogenolysis molecular biology pdh complex hypoglycemia glycogenesis biotin diabetes mellitus gluconeogenesis fatty liver enzyme kinetics quiz enzyme inhibition mutations atherosclerosis glucose statins tca cycle hyperlipidemia diabetic ketoacidosis glycolysis pyruvate carboxylase urea glucose alanine cycle role of insulin phosphorylase feedback inhibition case based discussions clinical cases allosteric modification rna pcr phospholipids fatty acid synthase complex acetyl co a acetyl co a carboxylase induction repression cofactors aspirin zellweger syndrome refsum disease digestion ldh cloning cholesterol katal starvation induced ketosis glycogen synthase transferase glycolipids nadph pdh complex deficiency. methylmalonic aciduria folate trap methylcobalamin megaloblastic anemia gene rearrangement gene amplification locus control regions lipoxins genetics thromboxane regulation of enzyme action leukotrienes zymogen activation mechanism of enzyme action prostacyclins absorption enzyme classification ligase hyperlipoprotenemia replication ourbiochemistry sickle cell anemia regulation lipid metabolism quick revisions calcium pyruvate fructose oxidative phosphorylation gaucher disease tay sach's disease hypolipidemic drugs chylomicrons niacin benedict's test rna editing fatty acid lactate secondary structure of protein sds page si rna vitamins alcoholism carnitine visuals alcohol gene expression blood glucose homeostasis glucagon carbohydrates hyperglycemia and glycosuria glucose transporters obesity molisch test osazone test inversion test hiv rna polymerase transcription base excision repair xeroderma pigmentosum nucleotide excision repair mismatch repair deamination wilson's disease copper cori cycle protein structure protein misfolding glucokinase fr 1 lysyl oxidase super oxide dismutase cytochrome oxidase citric acid cycle selenoproteins kreb cycle 2 3 bpg dhap keshan disease kashin-beck disease selenium poisoning glyceraldehyde-3-p ribonucleotide reductase hypolipoproteinemia arginosuccinic acid arginine uraemia citrulline ornithine carbamoyl p alanine hepatocuprein glutamine glutamate cerebrocuprein ammonia transdeamination transamination cerebro-hepato-lenticular degeneration 6 bisphosphatase menkes disease hexokinase vldl surface area and bmr glycated hb insulin fructosamine nephropathy retinopathy gangrene neuropathy cataract diabetic foot hyperosmolar non ketotic coma polyuria advanced glycation end products insulin resistance type 2 type 1 sorbitol alpha keto acid dehydrogenase complex ldl lipoprotein idl bmr hdl thyrotoxicosis and bmr transport of cholesterol variations of serum cholesterol levels ezetimibe myxedema and bmr cholesterol synthesis- details of steps pufa starvation and bmr c-peptide oral hypoglycemic drugs metformin microalbuminuria rothera's test thiazole deep vein thrombosis ph meter funnel watch glass digitalis flame photometer spectrophotometer hartnup disease tryptophan heparin gel electrophoresis immunoelectrophoresis paper electrophoresis slab electrophoresis egg white injury bial's test barfoed's test beauty vitamin glycosuria specific gravity ketonuria heat coagulation test phosphotungstic acid test sulppjosalicylic acid test jaffe;s reaction fehling test creatinine uric acid odour urinary ph rotheras test hypercalcemia hypocalcemia pth calcitonin calcitriol histone biotinylation promoter tata box transcription unit template pribnow box sulphur containing vitamin methyl crotonyl co a carboxylase dimers single base damage folic acid bloom syndrome pteroyl glutamic acid cross links glossitis hnpcc strand breaks two base damage erythrocuprein seliwanoff's test opportunistic infections holocarboxylase synthase deficiency full blown aids phase of sero conversion window period aids related complex persistent generalized lymphadenopathy acute hiv infection aids negative control positive control lac operon rifampicin mitomycin actinomycin splicing rho protein nag viral vectors artificial chromosomes citrate malonyl co a rflp southern blotting liposuction sibutramine stroke gene therapy coronary artery disease gene mapping transgenesis lactose intolerance gene disruption fibrinogen globulins albumin iron sulfur centres thermodynamic barrier enzymes activational barrier real time pcr sun screen lotions hypocalcaemia vitamin d taq man pcr assembly pcr lamp vectors hyperglycemia emphysema. juvenile cirrhosis plamids cosmids glycogen storage diseases bacteriophages b6 fructosemia hereditray fructose intoleranc udp glucose pyrimidines nucleotides nucleosides purines glycogenin affinity adsorption hplc and gas liquid chromatograohy ion exchange paper tlc debrabching enzyme pepsin proteins trypsin amino acid metabolism biowar vaccine recombinant proteins fatty acids cpk hepatitis muscle disorders acute mi gene cloning site specific mutagenesis pyruvate kinase deficiency galactosemia rl shunt inhibition prostglandins von gierke's disease glycogen metabolism glucosuria gamma counter melas cathepsins lada creatinine clearance m-rna r rna t-rna sn rna hn rna mi rna sickle beta thalassemia. hbsc hbs anemia. sickled red blood cells glass wares urine report blood biochemistry alpha keto glutarate dehydrogenase complex beriberi thiamine blood gas analyzer megx closed circuit method glutaminase respiratory acidosis open circuit method alpha helix read formula du-bois method for bsa calculation auto analyzer normal reference range protein synthesis srebp erucic acid chromatography reagents beta hydroxy butyrate acetone dna amplifcation forward primer hypoglycemia. dicarboxylic aciduria reverse primer rt pcr lipase nested pcr bile salts niemann pick's disease hot start pcr touchdown pcr cytochromes chemiosmosis ligase chain reaction ubiquinone spot questions reduction conjugation oxidation hydrolysis gall stones vitamin deficiencies biochemical techniques hypertension growth factors porphyrias graphs metabolic alkalosis urine analysis report inhibitor of electron transport chain starvation acetaldehyde taq polymerase glucose 6-phosphate fluroacetate uncompetitive inhibition suicidal inhibtion non-competitive inhibition competitive inhibition allosteric modulators effect of product on enzyme catalyzed reaction effect of substrate on enzyme catalyzed reaction temperature coefficient zero-order kinetics first-order kinetics iu/l product inhibition alzheimer's disease zymases coarse control fine control compartmentalization helicase dna polymerase quaternary structure microrna snrna hnrna ribozyme rrna trna mrna chargaff rule denaturation alzheimer disease prion disease protein unfolding transportation of acetyl coa high carb diet and lipogenesis malic enzyme prions diseases prosthetic group coenzymes tau protein case study iub classification isomerase dementia lyase hydrolase oxidoreductases xanthomas dysbetalipoproteinemia bovine spongiform encephalopathy mad cow disease lipoprotein metaboilsm lipoproteins chhabra enzyme linked immunosorbent assay prion protein covalent modification my role as a teacher bond strain acid-base catalysis proximity and orientation covalent catalsis thermodynamic perspective amyloid precursor protein a beta peptide enzyme specificity catalytic residues induced fit model lock and key model class-2 coenzymes class-1 coenzymes metal activated enzymes metalloenzymes cancers anti cancer drugs tumor markers tumor suppressor genes oncogenes proto oncogenes metabolic activation chemical carcinogens etiology of cancer biochemistry of cancer clofibrate alpha oxidation beta oxidation hemoprotein viral hepatitis physiological jaundice of the new born rotor syndrome criggler najjar syndrome multiple choice questions animal cloning applications of rdt structure and function relationship western hybridization northern hybridization southern hybridization recombinant dna technology gene expression in prokaryotes and eukaryotes post translational modifications post transcriptional modifications genetic code translation dna damage and repair isoenzymes uronic acid pathway hmp pathway glucose absorption post hepatic nonsense mutations missense silent mutations 迟谤补苍蝉惫别谤蝉颈贸苍 transition frameshift point mutations ataxia telengiectasia progeria ku protein homologous recombination excision repair direct repair mitosis proof reading ssb primase topoisomerase hepatic prehepatic jaundice variegate porphyria porphyria cutanea tarda acute intermittent porphyria congenital erythropoietic porphyria porphyria pophyrins heme primary structure beta thalassemia alpha thalassemia methemoglobinemia tertiary structure hemoglobinopathies hemoglobin chromosomal translocations waxes tpp pdh phosphatase liver cirrhosis hyperuricemia anion gap portal hypertension lactic acidosis bitot spots keratomalacia xerophthalmia night blindness wald's visual cycle anomers epimers aldose ketose isomers cyanocobalamin optical isomers adenosyl cobalamin monosaccharides oligosaccharides debranching enzyme polysaccharides phosphogluconate pentose phosphate hemplytic anemia g6pd starch adp creatine phosphate atp functions of atp amp substrate level phosphorylation coupling reactions asymmetric carbon atom pdh kinase pernicious anemia normal curve preparation of a patient intrinsic factor propionyl co a carboxylase tourniquette test petechiae subconjuctival hemorrahges subperiosteal hemorrhages collagen scurvy ascorbic acid vitamin c vitamin c deficiency heller;s ring test proteinuria hay sulphur test volume urinalysis class switching m rna stability stereoisomers fischer projection haworth projection chair and boat conformation sugar alcohols sugar acids vitamin b12 cyno cobamlamine lag curve precautions criteria for diagnosis of dm renal glycosuria contraindications glucose tolerance test- indications diabetic curve types of gtt steroids nsaids pgh synthase cyclogenase prostaglandins eicosanoids ige igd igm igg immuniglobulins indirect elisa sandwich elisa factors affecting enzyme activity zero order kinetics first order kinetics competitive elisa km fats sphingolipidosis lipid storage diseases presentations hypervitaminosis medicine minerals m.b.b.s elisa principle of elisa types of elisa carbohydrate metabolism lipid chemistry chemistry of carbohydrates team based learning direct elisa srsa inflammation immunodeficiency transmthylation millon test transaminaton hopekin cole test biuret test decarboxylation glucogenic imino acids amino acids heterocyclic kteogenic classification aromatic ketone bodies elisa in hiv infection thiophorase ketosis thiolase pnemocystis pneumonia kaposi sarcoma retrovirus cd4 haart warfarin vitamin k cycle namrata vitamin k ideal medical teacher who initiatives of faculty development multiple roles of a teacher faculty development hierarchy of faculty development strategies medical education xanthoproteic test ninhydrin test sakaguchi test benedict;s test