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dental microbiology dentist oral microbiology dentistry caries dental caries developmental disorder plaque teeth streptococcus bacteria rotten teeth diagnosis taxonomy organism periodontium gums oral pathology periodontal disease media culture microorganisms microorganism oral biota hypodontia teratogenic oral hard tissue genetics mesodens hyperdontia congenital disorders ectoderman dysplasia hard tissue hereditary disorders tooth decay zones of caries survival acute inflammation medicine chronic inflammation inflammation cleft lip cleft palate radiograph pathology of caries rampant caries proximal caries oral flora