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CHARACTERIZED, TESTED AND DISCOVERY
READY FOR RESULTSYOU CANTRUST AND UNDERSTAND
Solutions Designed for Drug Discovery
and Basic Research www.neuromics.com
OUR CORNERSTONE: HUMAN PRIMARY CELLS AND 3-D
TISSUE MODELS, DEFINED MEDIA AND FBS
2 and 3-D Cell
Based Assays
>250 peer
Reviewed
Publications
3-DTissue-Like
Models
Primary Human
Neuron,Astrocytes and
Microglia
Primary Human
Endothelial Cells and
Pericytes
Cancer Associated
Fibroblasts andTumor
Cells
Human MSCs and
Derived Cells
Primary Antibodies &
Markers
Apoptosis Kits
GeneTools
Proteins and Growth
Factors
Protein Generation &
Purification
FBS, Media & Culturing
Products
RESULTSYOU CAN TRUST AND UNDERSTAND
3rd Party Service For Customer Feedback
Neuromics review summary
Sample Reviews:
Ravi D.on BirdEye
We have ordered Brain derived Endothelial Cells or BECs.We could not find these in different companies,
particularly from multiple donors. Overall, we are happy with the products.
Olesya P.on BirdEye
We bought a large order of FBS from Neuromics. Our experience with their customer service was great.They
offered us the best price and worked with us on any issue issues that came up on our side.
Jiehua Z.on BirdEye
We ordered the cells, medium and related culture product. Fast ordering and delivery procedure, and nice
technique support.The cells grew well as described and we can easily expand them.
HBMECs Stained with CD146
HUMAN PRIMARY CELLS
Neurons, Astrocytes, Schwann Cells and
Microglia
Endothelial Cells
Fibroblasts, CAFs and Cancer
Cells
Human Brain Microvascular Endothelial Cells stained with CD146
HUMAN BBB MODEL TEST APPLICATIONS
 Permeability Studies -Compounds, Oligos and Small Molecules :
 General Procedure
 3D Blood Brain Barrier models are thawed and cultured for
4 days to establish viable barrier as measured by
transendothelial electrical resistance (> 150 立 x cm2).
 The test compound and fluorescent probe are added and
the cultures are returned to incubate for designated times.
 If assessment of alterations to BBB permeability due to
drug treatment is required, fluorescent dextran conjugate is
added to wells
 Media is sampled for quantitation of test articles by UPLC,
and for quantification of fluorescent probe by plate reader
 Apparent permeability is calculated
Bottom Figure:Alterations in apparent permeability of blood brain barrier due to drug
treatment. Data presented as mean 賊 SEM x 10-6 cm/s. * Indicates p<0.05 for Fishers
LSD t-test comparisons to DMSO controls in a post hoc analysis following two-way
ANOVA. Data Courtsey ofVisokol
 ;
CANCER ASSOCIATED FIBROBLASTS AND GFP-
RFP EXPRESSING CARCINOMA CELL LINES
 Gastric Carcinoma 87
 Top image: RFP Expressing Gastric Carcinoma 87 Cells  cat no.
TR02-RFP
 Glioblastoma
 Prostate Carcinoma Cells (DU 145)
 Renal Adenocarcinoma Cells (ACHN)
 Bottom image: GFP-Expressing Renal Adenocarcinoma Cells  cat
no.TR04-GFP
Neuromics is the U.S. Distributor for IBA Lifesciences Solutions
cell selection & expansion.
exosome isolation.
protein production & assays.
Fetal Bovine Serum (FBS)
 Manufactured under the
strictest guidelines
 Triple filtered, single Use
filters
 Lowest price anywhere
 Compare and save
ANTIBODIES
 Antibodies for many research areas:
 Neuroscience
 Apoptosis
 Cancer
 Angiogenesis
 Diabetes and Obesity
 Immune Response
 Stem Cell Research
 Musculoskeletal Disease
Image: PGP9.5 (cat no. RA12103) staining of rat
DRGs (Dilution 1:500)
Phone: 952-374-616
Fax: 612-677-3976
Email: david@neuromics.com for orders and tech questions
We welcome your input, feedback and questions:
Pete Shuster-CEO and Owner
Direct Phone: 612-801-1007
Email: pshuster@neuromics.com
5235 W 74th Street Suite 8
Edina, MN, 55439
www.neuromics.com Find us on
 Get Exclusive Discounts and Special offers
 New Product Updates
 Researcher Insights
 The Latest in Neuroscience News
Ad

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Neuromics' Short Overview

  • 1. CHARACTERIZED, TESTED AND DISCOVERY READY FOR RESULTSYOU CANTRUST AND UNDERSTAND Solutions Designed for Drug Discovery and Basic Research www.neuromics.com
  • 2. OUR CORNERSTONE: HUMAN PRIMARY CELLS AND 3-D TISSUE MODELS, DEFINED MEDIA AND FBS 2 and 3-D Cell Based Assays >250 peer Reviewed Publications 3-DTissue-Like Models Primary Human Neuron,Astrocytes and Microglia Primary Human Endothelial Cells and Pericytes Cancer Associated Fibroblasts andTumor Cells Human MSCs and Derived Cells Primary Antibodies & Markers Apoptosis Kits GeneTools Proteins and Growth Factors Protein Generation & Purification FBS, Media & Culturing Products
  • 3. RESULTSYOU CAN TRUST AND UNDERSTAND 3rd Party Service For Customer Feedback Neuromics review summary Sample Reviews: Ravi D.on BirdEye We have ordered Brain derived Endothelial Cells or BECs.We could not find these in different companies, particularly from multiple donors. Overall, we are happy with the products. Olesya P.on BirdEye We bought a large order of FBS from Neuromics. Our experience with their customer service was great.They offered us the best price and worked with us on any issue issues that came up on our side. Jiehua Z.on BirdEye We ordered the cells, medium and related culture product. Fast ordering and delivery procedure, and nice technique support.The cells grew well as described and we can easily expand them. HBMECs Stained with CD146
  • 4. HUMAN PRIMARY CELLS Neurons, Astrocytes, Schwann Cells and Microglia Endothelial Cells Fibroblasts, CAFs and Cancer Cells Human Brain Microvascular Endothelial Cells stained with CD146
  • 5. HUMAN BBB MODEL TEST APPLICATIONS Permeability Studies -Compounds, Oligos and Small Molecules : General Procedure 3D Blood Brain Barrier models are thawed and cultured for 4 days to establish viable barrier as measured by transendothelial electrical resistance (> 150 立 x cm2). The test compound and fluorescent probe are added and the cultures are returned to incubate for designated times. If assessment of alterations to BBB permeability due to drug treatment is required, fluorescent dextran conjugate is added to wells Media is sampled for quantitation of test articles by UPLC, and for quantification of fluorescent probe by plate reader Apparent permeability is calculated Bottom Figure:Alterations in apparent permeability of blood brain barrier due to drug treatment. Data presented as mean 賊 SEM x 10-6 cm/s. * Indicates p<0.05 for Fishers LSD t-test comparisons to DMSO controls in a post hoc analysis following two-way ANOVA. Data Courtsey ofVisokol ;
  • 6. CANCER ASSOCIATED FIBROBLASTS AND GFP- RFP EXPRESSING CARCINOMA CELL LINES Gastric Carcinoma 87 Top image: RFP Expressing Gastric Carcinoma 87 Cells cat no. TR02-RFP Glioblastoma Prostate Carcinoma Cells (DU 145) Renal Adenocarcinoma Cells (ACHN) Bottom image: GFP-Expressing Renal Adenocarcinoma Cells cat no.TR04-GFP
  • 7. Neuromics is the U.S. Distributor for IBA Lifesciences Solutions cell selection & expansion. exosome isolation. protein production & assays.
  • 8. Fetal Bovine Serum (FBS) Manufactured under the strictest guidelines Triple filtered, single Use filters Lowest price anywhere Compare and save
  • 9. ANTIBODIES Antibodies for many research areas: Neuroscience Apoptosis Cancer Angiogenesis Diabetes and Obesity Immune Response Stem Cell Research Musculoskeletal Disease Image: PGP9.5 (cat no. RA12103) staining of rat DRGs (Dilution 1:500)
  • 10. Phone: 952-374-616 Fax: 612-677-3976 Email: david@neuromics.com for orders and tech questions We welcome your input, feedback and questions: Pete Shuster-CEO and Owner Direct Phone: 612-801-1007 Email: pshuster@neuromics.com 5235 W 74th Street Suite 8 Edina, MN, 55439 www.neuromics.com Find us on Get Exclusive Discounts and Special offers New Product Updates Researcher Insights The Latest in Neuroscience News