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The time has come to teach arts and science together. Physicists, students, and physics lovers worldwide, and all others can use poetry and various art forms to capture the essence of science to enhance learning. Science, technology, engineering, arts, and mathematics (S.T.E.A.M.) come together in this talk, from the perspective of a physician, poet, and scientist.
Read more about creative expression in science and medicine relevant to the brain at http://journal.frontiersin.org/article/10.3389/fneur.2015.00003/full
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Constructing S.T.E.A.M.: a PHYSICSian scientist’s perspective
5. The Cerebellum
• Latin, little brain
• Constitutes only 10% of the total volume of the brain, but contains more
than half of all its neurons
• Coordinates posture, gaze, speech, handwriting, and other motor functions
The Cerebellum, Principles of Neural Science. 2000 McGraw Hill.
ATAXIA
n. Greek. Loss of motor coordination.
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10. Hernjak et al, Biophysical Journal 2005
Parallel fiber
stimulus
Climbing fiber
stimulus
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Calcium Pathways In The Cell
Aim 1:
3D Model
12. Hernjak et al, Biophysical Journal 2005
Parallel fiber
stimulus
Climbing fiber
stimulus
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Calcium Pathways In The Cell
Aim 1:
3D Model
13. PIP2 Diffusion in the spine membrane
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Max
8120
1400
Min
14. SIX Spines - Simulation
Max
8120
1400
Min
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16. Hernjak et al, Biophysical Journal 2005
Parallel fiber
stimulus
Climbing fiber
stimulus
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Calcium Pathways In The Cell
Aim 1:
3D Model
Aim 2:
Electric
Model
20. Comparison of Electrical Activity in
the Full and Reduced Models - soma
-80
-40
0
40
80
0 500Time (ms)
Membrane
Potential(mV)
-80
-40
0
40
80
0 500Time (ms)
Membrane
Potential(mV)
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Full model Reduced model
21. Hernjak et al, Biophysical Journal 2005
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Calcium Pathways In The Cell
Aim 3:
Ataxia
Model
Aim 1:
3D Model
Aim 2:
Electric
Model
28. My Thesis Committee
CCAM, MD/PhD Program
University of Connecticut Health Center
NIH
Primary Investigator:
Dr. Leslie M. Loew Dr. Ion Moraru
Dr. James Schaff
Dr. Ann Cowan
Dr. Raquell Holmes
Dr. James Watras
Mr. Frank Morgan
Ed & Elena
Karen, Donna,
Debbie
Anu, Fei, Li
Ye; Boris,
Igor, Pavel
Sofya,
Jon,
Stacy
Dr. Art Hand
Dr. Bill Lytton
Dr. Marja Hurley
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29. Stepping In & Out
Sherry-Ann Brown, MD, PhD
CI Planning Meeting 2015
Thesis reception: S.T.E.A.M. poetry collection poster, art & photography
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37. Ohm’s Law & Blood Circulation
Ohms Law Darcy’s Law
V = I x R BP = Q x VR
"The heart is the only organ of all organs that can not endure injury. This is expected
because when the main power source is destroyed, no additional force can be brought
by the organs that depend on it" (Aristotle - 384 BC).
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38. • In a noncompressible fluid system, flow is the same
at any given point
• Flow = area x velocity
• area x velocity = area x velocity
• F ∝ V ⋅ r2
cm³►cm² cmx
Conservation of Mass Principle
Compliments of Dr. Hector Michelena, Mayo Clinic
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