際際滷

際際滷Share a Scribd company logo

Embase advanced-training-slidespdf (2)

R
rosie.dunne

Embase advanced training on systematic reviews NUI Galway 16 September 2020 Presenter: Giulia Moncelsi | Customer Consultant, Life Sciences

Convert to study guideBETA

Transform any presentation into a summarized study guide, highlighting the most important points and key insights.

1 of 60
Download to read offline
September 16th, 2020 Dr. Giulia Moncelsi, Customer Consultant in Life Sciences g.moncelsi@elsevier.com Using Embase速 for systematic reviews
Agenda Quick Embase refresher Indexing and content Overview of the search interface and features Searching the database: focus on systematic reviews Browse Emtree and Advanced Search PICO search module for SRs and meta analyses. Use cases: The effectiveness of online or app based psychological interventions in the reduction of postoperative pain, pain related interference or disability Virtual Reality to assist older adults with dementia / Alzheimers disease Q&A 2
What is Embase?
| 4 What is Embase? Peer-reviewed content Embase indexers extract relevant concepts from full text articles Index terms are standard according to the Emtree thesaurus Manually curated content is available for search and retrieval A biomedical literature database with the most comprehensive coverage and indexing of journals and conferences Drug names Device names Disease names and moreControlled vocabulary updated 3x year
How does Embase work? Conference proceedings Literature and information resources added in a timely manner. Full-text reading to identify drugs, diseases, adverse effects, clinical trials, drug trade names, etc. Advanced search filters to refine a comprehensive search to a relevant and manageable record set. Scientific Journals In Press (unpublished) Automate searching and results management. We ensure you dont miss any critical biomedical literature. The nearest alternative would be reading all the articles yourself. Results are an excellent balance between precision and recall. Workflows can be semi- automated and integrated with other solutions. Deep indexing using own life sciences taxonomy (Emtree) Very powerful search environment (PV Wizard, adverse event parameters, dedicated filters) Email alerts API InteroperabilityTrackable search history
Embase is the most comprehensive biomedical literature database In-depth drug, disease, device indexing Unique search features Ability to save, share and edit complex search strategies with a group Unique coverage of over 2M conference abstracts from >6,000 conferences (added since 2009) Much more coverage of non-English content and Randomized Controlled Trials Embase MEDLINE 2,900+ journals not available on MEDLINE Over 8,300 Journals/ 34+ Million Records. Recommended by (regulatory) authorities: EMA for Pharmacovigilance European Commission for Clinical Evaluation Reporting of medical devices Cochrane, WHO and NICE for Evidence Based Medicine (systematic reviews and guidelines)
Explore Emtree Preferred term (/de) Narrower terms are included in an explosion search (/exp) Synonyms are mapped and searched irrespective of mapping level A hierarchically structured, controlled vocabulary for biomedicine and the related life sciences.
Indexing: triple-linking Triple-linking is a three-level indexing of the full text of an article, and it consists of: Concept (drug, device or disease) Key subheading (relationship) Linked concept (e.g. device, stomatitis, hypertension, nausea, etc.) Atrial fibrillation Drug therapy Warfarin Manually Extracted Semantic Relationships
Search tools in Embase Browse Emtree (search terminology) Journals Others Syntax: proximity operators: NEAR, NEXT; wildcards: ?, *, $ Index miner Find similar records Insertion of list of synonyms directly in PICO and PV Wizard search forms Search Quick Advanced Drug Disease Medical device Article PICO PV Wizard Author
Resources on Embase at NUI Galway https://libguides.library.nuigalway.ie/c.php?g=541126&p=4860533
Computer Programs for Semi-Automation of Evidence Synthesis https://www.brighttalk.com/webcast/16527/392278/computer-programs-for-semi-automation-of-evidence-synthesis
How to build a comprehensive drug safety search strategy The PV Wizard is an intuitive query builder that has a pre-coded pharmacovigilance search strategy constructed in consultation with pharma industry partners. Enter drug name Select and click Review Review Review and Show results Select and click
Finding the best evidence What are Systematic Reviews? High-level overviews of primary research that tries to identify, select, synthesize and appraise all high-quality research evidence relevant to that question. Ref: EBM Resource Pyramid https://hsls.libguides.com/pyramid
The 5 steps of evidence-based practice Step 1. Ask the question: expressing the problem as a clinical question Step 2. Acquire the best available evidence and as comprehensive as possible: finding evidence-based resources that answer the question Step 3. Appraise the evidence: critically appraising the evidence to assess its validity Step 4. Apply the evidence Step 5. Re-evaluate the evidence and its application Ref.: https://www.elsevier.com/books/evidence-based-medicine/straus/978-0-7020-6296-4
Major organizations for systematic reviews in healthcare and policy Cochrane database of systematic reviews (UK) JBI research organisation at the University of Adelaide (Australia) The Campbell Collaboration social science research network (Norway) The Centre for Reviews and Dissemination at the University of York (UK)
Finding evidence-based resources that answer the question Ref: Embase.com, search performed on Jan 16, 2018 0 5000 10000 15000 20000 25000 30000 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 The Growing of Systematic Reviews SR Records in Embase SR referencing Embase
| 17 Using the PICO search framework to structure a question P = Patient/population/problem I = Intervention C = Comparison/control O = Outcome PICO is a method to structure the elements (concepts) of a clinical question into a search strategy.
Live Demo Focus on systematic reviews
Use cases from research students The effectiveness of online or app-based psychological interventions in the reduction of postoperative pain, pain-related interference or disability: A systematic review and meta-analysis The use of Virtual Reality to assist older adults with dementia / Alzheimers disease
Use case 1 The effectiveness of online or app-based psychological interventions in the reduction of postoperative pain, pain-related interference or disability: A systematic review and meta-analysis
Explore Embase Support Hub
Embase advanced-training-slidespdf (2)
Conduct a scoping search for one or more elements of your question
Start within Browse Emtree
Identify the preferred term
Look at the Emtree structure And check the history and taxonomy of terms
Add terms to the query builder
Expand your search Add to the query builder
Substitute OR with AND operator to include more results
Include more terms Substitute OR with AND operator
Then take the query to the Advanced Search
Edit your search string with the appropriate field codes and limitations Focus on evidence-based medicine
Check the state-of-the-art literature between 2015-2020
Explore the records
Look for a search strategy within a systematic review
Go back to the search tab Assess the search strategy relevance for adaptation Translate the search syntax, when necessary Consider free text terms used Convert subject terms, where needed Consider indexed terms (subject headings) ... And author keywords
Go to the PICO tab After the scoping search, we frame the question or research hypothesis by filling the PICO elements
Decide your preferred mapping option Every string is connected by an AND operator Type in or browse your search
Terms on the same string are connected by an OR operator Add and select your synonyms Choose your preferred mapping option
Change the OR to AND or other operators
Embase advanced-training-slidespdf (2)
Check the results
Look for PICO input information to refine your question within the publication(s) retrieved
Use case 2 The use of Virtual Reality to assist older adults with dementia / Alzheimers disease
Use PICO again
Carefully fill one or more elements of the PICO search
Filter by the desired EBM
Look at Publications years to check the latest SRs written 2017? Worth it to write a new one 2019-2020: consider changing topic
Select the SRs, assess their scope to make sure it wont be redundant
Embase advanced-training-slidespdf (2)
Check the the full list of indexed terms
Embase advanced-training-slidespdf (2)
Save search(es) and find them in My tools
Rerun and check if new terms have been added to the Emtree Use the Saved Searches tab Always see traceability
Set up an email alert Follow any systematic review on that topic and be up-to-date with new literature or academic collaborations
Set up an email alert
Select and export your results Scroll down and
Chose the preferred format and export
There is no perfect way to search! An effective search is an iterative process: it involves narrowing or widening your search strategy after finding relevant information, the search statement is revised based on what you did (or did not) find the search is refined accordingly It is a process of constant modification of the basic search, often requiring extensive practice with the database(s) and expertise in the topic searched.
Thank you

More Related Content

Embase advanced-training-slidespdf (2)

  • 1. September 16th, 2020 Dr. Giulia Moncelsi, Customer Consultant in Life Sciences g.moncelsi@elsevier.com Using Embase速 for systematic reviews
  • 2. Agenda Quick Embase refresher Indexing and content Overview of the search interface and features Searching the database: focus on systematic reviews Browse Emtree and Advanced Search PICO search module for SRs and meta analyses. Use cases: The effectiveness of online or app based psychological interventions in the reduction of postoperative pain, pain related interference or disability Virtual Reality to assist older adults with dementia / Alzheimers disease Q&A 2
  • 4. | 4 What is Embase? Peer-reviewed content Embase indexers extract relevant concepts from full text articles Index terms are standard according to the Emtree thesaurus Manually curated content is available for search and retrieval A biomedical literature database with the most comprehensive coverage and indexing of journals and conferences Drug names Device names Disease names and moreControlled vocabulary updated 3x year
  • 5. How does Embase work? Conference proceedings Literature and information resources added in a timely manner. Full-text reading to identify drugs, diseases, adverse effects, clinical trials, drug trade names, etc. Advanced search filters to refine a comprehensive search to a relevant and manageable record set. Scientific Journals In Press (unpublished) Automate searching and results management. We ensure you dont miss any critical biomedical literature. The nearest alternative would be reading all the articles yourself. Results are an excellent balance between precision and recall. Workflows can be semi- automated and integrated with other solutions. Deep indexing using own life sciences taxonomy (Emtree) Very powerful search environment (PV Wizard, adverse event parameters, dedicated filters) Email alerts API InteroperabilityTrackable search history
  • 6. Embase is the most comprehensive biomedical literature database In-depth drug, disease, device indexing Unique search features Ability to save, share and edit complex search strategies with a group Unique coverage of over 2M conference abstracts from >6,000 conferences (added since 2009) Much more coverage of non-English content and Randomized Controlled Trials Embase MEDLINE 2,900+ journals not available on MEDLINE Over 8,300 Journals/ 34+ Million Records. Recommended by (regulatory) authorities: EMA for Pharmacovigilance European Commission for Clinical Evaluation Reporting of medical devices Cochrane, WHO and NICE for Evidence Based Medicine (systematic reviews and guidelines)
  • 7. Explore Emtree Preferred term (/de) Narrower terms are included in an explosion search (/exp) Synonyms are mapped and searched irrespective of mapping level A hierarchically structured, controlled vocabulary for biomedicine and the related life sciences.
  • 8. Indexing: triple-linking Triple-linking is a three-level indexing of the full text of an article, and it consists of: Concept (drug, device or disease) Key subheading (relationship) Linked concept (e.g. device, stomatitis, hypertension, nausea, etc.) Atrial fibrillation Drug therapy Warfarin Manually Extracted Semantic Relationships
  • 9. Search tools in Embase Browse Emtree (search terminology) Journals Others Syntax: proximity operators: NEAR, NEXT; wildcards: ?, *, $ Index miner Find similar records Insertion of list of synonyms directly in PICO and PV Wizard search forms Search Quick Advanced Drug Disease Medical device Article PICO PV Wizard Author
  • 10. Resources on Embase at NUI Galway https://libguides.library.nuigalway.ie/c.php?g=541126&p=4860533
  • 11. Computer Programs for Semi-Automation of Evidence Synthesis https://www.brighttalk.com/webcast/16527/392278/computer-programs-for-semi-automation-of-evidence-synthesis
  • 12. How to build a comprehensive drug safety search strategy The PV Wizard is an intuitive query builder that has a pre-coded pharmacovigilance search strategy constructed in consultation with pharma industry partners. Enter drug name Select and click Review Review Review and Show results Select and click
  • 13. Finding the best evidence What are Systematic Reviews? High-level overviews of primary research that tries to identify, select, synthesize and appraise all high-quality research evidence relevant to that question. Ref: EBM Resource Pyramid https://hsls.libguides.com/pyramid
  • 14. The 5 steps of evidence-based practice Step 1. Ask the question: expressing the problem as a clinical question Step 2. Acquire the best available evidence and as comprehensive as possible: finding evidence-based resources that answer the question Step 3. Appraise the evidence: critically appraising the evidence to assess its validity Step 4. Apply the evidence Step 5. Re-evaluate the evidence and its application Ref.: https://www.elsevier.com/books/evidence-based-medicine/straus/978-0-7020-6296-4
  • 15. Major organizations for systematic reviews in healthcare and policy Cochrane database of systematic reviews (UK) JBI research organisation at the University of Adelaide (Australia) The Campbell Collaboration social science research network (Norway) The Centre for Reviews and Dissemination at the University of York (UK)
  • 16. Finding evidence-based resources that answer the question Ref: Embase.com, search performed on Jan 16, 2018 0 5000 10000 15000 20000 25000 30000 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 The Growing of Systematic Reviews SR Records in Embase SR referencing Embase
  • 17. | 17 Using the PICO search framework to structure a question P = Patient/population/problem I = Intervention C = Comparison/control O = Outcome PICO is a method to structure the elements (concepts) of a clinical question into a search strategy.
  • 18. Live Demo Focus on systematic reviews
  • 19. Use cases from research students The effectiveness of online or app-based psychological interventions in the reduction of postoperative pain, pain-related interference or disability: A systematic review and meta-analysis The use of Virtual Reality to assist older adults with dementia / Alzheimers disease
  • 20. Use case 1 The effectiveness of online or app-based psychological interventions in the reduction of postoperative pain, pain-related interference or disability: A systematic review and meta-analysis
  • 23. Conduct a scoping search for one or more elements of your question
  • 26. Look at the Emtree structure And check the history and taxonomy of terms
  • 27. Add terms to the query builder
  • 28. Expand your search Add to the query builder
  • 29. Substitute OR with AND operator to include more results
  • 30. Include more terms Substitute OR with AND operator
  • 31. Then take the query to the Advanced Search
  • 32. Edit your search string with the appropriate field codes and limitations Focus on evidence-based medicine
  • 33. Check the state-of-the-art literature between 2015-2020
  • 35. Look for a search strategy within a systematic review
  • 36. Go back to the search tab Assess the search strategy relevance for adaptation Translate the search syntax, when necessary Consider free text terms used Convert subject terms, where needed Consider indexed terms (subject headings) ... And author keywords
  • 37. Go to the PICO tab After the scoping search, we frame the question or research hypothesis by filling the PICO elements
  • 38. Decide your preferred mapping option Every string is connected by an AND operator Type in or browse your search
  • 39. Terms on the same string are connected by an OR operator Add and select your synonyms Choose your preferred mapping option
  • 40. Change the OR to AND or other operators
  • 43. Look for PICO input information to refine your question within the publication(s) retrieved
  • 44. Use case 2 The use of Virtual Reality to assist older adults with dementia / Alzheimers disease
  • 46. Carefully fill one or more elements of the PICO search
  • 47. Filter by the desired EBM
  • 48. Look at Publications years to check the latest SRs written 2017? Worth it to write a new one 2019-2020: consider changing topic
  • 49. Select the SRs, assess their scope to make sure it wont be redundant
  • 51. Check the the full list of indexed terms
  • 53. Save search(es) and find them in My tools
  • 54. Rerun and check if new terms have been added to the Emtree Use the Saved Searches tab Always see traceability
  • 55. Set up an email alert Follow any systematic review on that topic and be up-to-date with new literature or academic collaborations
  • 56. Set up an email alert
  • 57. Select and export your results Scroll down and
  • 59. There is no perfect way to search! An effective search is an iterative process: it involves narrowing or widening your search strategy after finding relevant information, the search statement is revised based on what you did (or did not) find the search is refined accordingly It is a process of constant modification of the basic search, often requiring extensive practice with the database(s) and expertise in the topic searched.