�ݺ�ߣshows by User: RAGHUNATHKARMAKER1

�ݺ�ߣshows by User: RAGHUNATHKARMAKER1 / http://www.slideshare.net/images/logo.gif �ݺ�ߣshows by User: RAGHUNATHKARMAKER1 / Fri, 22 Nov 2024 10:49:58 GMT �ݺ�ߣShare feed for �ݺ�ߣshows by User: RAGHUNATHKARMAKER1 NEUROBLASTOMA in children topic presentation.pptx /slideshow/neuroblastoma-in-children-topic-presentation-pptx/273522745 neuroblastomatopicpresentation-241122104958-17210b5c
Neuroblastoma Neuroblastoma is a malignant tumor originating from neural crest cells of the sympathetic nervous system. It is the most common extracranial solid tumor in children, typically affecting those under 5 years old. Clinical Features Abdominal mass: Most common presentation, often involving the adrenal gland. Systemic symptoms: Fever, weight loss, fatigue. Paraneoplastic syndromes: Hypertension, opsoclonus-myoclonus syndrome. Metastases: Bone pain, proptosis, periorbital ecchymosis. Diagnosis Imaging: Ultrasound, CT, or MRI shows the tumor and possible spread. Urine catecholamines: Elevated levels of vanillylmandelic acid (VMA) and homovanillic acid (HVA). Biopsy: Confirms diagnosis and assesses histopathology. Staging: Uses the International Neuroblastoma Staging System (INSS). Management Low-risk: Surgery alone may suffice. Intermediate/high-risk: Combination of chemotherapy, surgery, radiation, and stem cell transplant. Targeted therapy: Immunotherapy and retinoids for high-risk cases. Prognosis Depends on age, stage, and tumor biology. Children under 18 months with localized tumors have a good prognosis, while advanced or metastatic cases are more challenging. ]]>
Neuroblastoma Neuroblastoma is a malignant tumor originating from neural crest cells of the sympathetic nervous system. It is the most common extracranial solid tumor in children, typically affecting those under 5 years old. Clinical Features Abdominal mass: Most common presentation, often involving the adrenal gland. Systemic symptoms: Fever, weight loss, fatigue. Paraneoplastic syndromes: Hypertension, opsoclonus-myoclonus syndrome. Metastases: Bone pain, proptosis, periorbital ecchymosis. Diagnosis Imaging: Ultrasound, CT, or MRI shows the tumor and possible spread. Urine catecholamines: Elevated levels of vanillylmandelic acid (VMA) and homovanillic acid (HVA). Biopsy: Confirms diagnosis and assesses histopathology. Staging: Uses the International Neuroblastoma Staging System (INSS). Management Low-risk: Surgery alone may suffice. Intermediate/high-risk: Combination of chemotherapy, surgery, radiation, and stem cell transplant. Targeted therapy: Immunotherapy and retinoids for high-risk cases. Prognosis Depends on age, stage, and tumor biology. Children under 18 months with localized tumors have a good prognosis, while advanced or metastatic cases are more challenging. ]]> Fri, 22 Nov 2024 10:49:58 GMT /slideshow/neuroblastoma-in-children-topic-presentation-pptx/273522745 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) NEUROBLASTOMA in children topic presentation.pptx RAGHUNATHKARMAKER1 Neuroblastoma Neuroblastoma is a malignant tumor originating from neural crest cells of the sympathetic nervous system. It is the most common extracranial solid tumor in children, typically affecting those under 5 years old. Clinical Features Abdominal mass: Most common presentation, often involving the adrenal gland. Systemic symptoms: Fever, weight loss, fatigue. Paraneoplastic syndromes: Hypertension, opsoclonus-myoclonus syndrome. Metastases: Bone pain, proptosis, periorbital ecchymosis. Diagnosis Imaging: Ultrasound, CT, or MRI shows the tumor and possible spread. Urine catecholamines: Elevated levels of vanillylmandelic acid (VMA) and homovanillic acid (HVA). Biopsy: Confirms diagnosis and assesses histopathology. Staging: Uses the International Neuroblastoma Staging System (INSS). Management Low-risk: Surgery alone may suffice. Intermediate/high-risk: Combination of chemotherapy, surgery, radiation, and stem cell transplant. Targeted therapy: Immunotherapy and retinoids for high-risk cases. Prognosis Depends on age, stage, and tumor biology. Children under 18 months with localized tumors have a good prognosis, while advanced or metastatic cases are more challenging. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/neuroblastomatopicpresentation-241122104958-17210b5c-thumbnail.jpg?width=120&height=120&fit=bounds" /> Neuroblastoma Neuroblastoma is a malignant tumor originating from neural crest cells of the sympathetic nervous system. It is the most common extracranial solid tumor in children, typically affecting those under 5 years old. Clinical Features Abdominal mass: Most common presentation, often involving the adrenal gland. Systemic symptoms: Fever, weight loss, fatigue. Paraneoplastic syndromes: Hypertension, opsoclonus-myoclonus syndrome. Metastases: Bone pain, proptosis, periorbital ecchymosis. Diagnosis Imaging: Ultrasound, CT, or MRI shows the tumor and possible spread. Urine catecholamines: Elevated levels of vanillylmandelic acid (VMA) and homovanillic acid (HVA). Biopsy: Confirms diagnosis and assesses histopathology. Staging: Uses the International Neuroblastoma Staging System (INSS). Management Low-risk: Surgery alone may suffice. Intermediate/high-risk: Combination of chemotherapy, surgery, radiation, and stem cell transplant. Targeted therapy: Immunotherapy and retinoids for high-risk cases. Prognosis Depends on age, stage, and tumor biology. Children under 18 months with localized tumors have a good prognosis, while advanced or metastatic cases are more challenging.

NEUROBLASTOMA in children topic presentation.pptx from RAGHUNATHKARMAKER1

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0 long case,Wilms tumor Copy most common renal malignancy in children.pptx /slideshow/long-case-wilms-tumor-copy-most-common-renal-malignancy-in-children-pptx/273522675 longcasewilmstumorcopy-241122104653-4cf9f975
Wilms Tumor (Nephroblastoma) Wilms tumor is the most common renal malignancy in children, typically occurring before the age of 5. It arises from immature kidney cells and is associated with genetic mutations, such as those in the WT1 or WT2 genes.]]>
Wilms Tumor (Nephroblastoma) Wilms tumor is the most common renal malignancy in children, typically occurring before the age of 5. It arises from immature kidney cells and is associated with genetic mutations, such as those in the WT1 or WT2 genes.]]> Fri, 22 Nov 2024 10:46:53 GMT /slideshow/long-case-wilms-tumor-copy-most-common-renal-malignancy-in-children-pptx/273522675 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) long case,Wilms tumor Copy most common renal malignancy in children.pptx RAGHUNATHKARMAKER1 Wilms Tumor (Nephroblastoma) Wilms tumor is the most common renal malignancy in children, typically occurring before the age of 5. It arises from immature kidney cells and is associated with genetic mutations, such as those in the WT1 or WT2 genes. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/longcasewilmstumorcopy-241122104653-4cf9f975-thumbnail.jpg?width=120&height=120&fit=bounds" /> Wilms Tumor (Nephroblastoma) Wilms tumor is the most common renal malignancy in children, typically occurring before the age of 5. It arises from immature kidney cells and is associated with genetic mutations, such as those in the WT1 or WT2 genes.

long case,Wilms tumor Copy most common renal malignancy in children.pptx from RAGHUNATHKARMAKER1

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0 DSD ( disorders of sexual development).pptx /slideshow/dsd-disorders-of-sexual-development-pptx/273522480 dsddisordersofsexualdevelopment-241122103750-9146407a
Disorders of Sex Development (DSD) in Children Disorders of Sex Development (DSD) refer to congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is atypical. These conditions can present in various forms, such as ambiguous genitalia, discrepancies between chromosomal and phenotypic sex, or atypical gonadal development. Classification DSD can be categorized into: 1. 46,XX DSD: Typically involves virilization of genetic females (e.g., congenital adrenal hyperplasia). 2. 46,XY DSD: Typically involves undervirilization of genetic males (e.g., androgen insensitivity syndrome). 3. Sex Chromosome DSD: Includes conditions like Turner syndrome (45,X) and Klinefelter syndrome (47,XXY). Clinical Presentation Ambiguous genitalia at birth (e.g., clitoromegaly, hypospadias, cryptorchidism). Discordance between prenatal sex determination and genital appearance. Delayed or abnormal puberty. Management Immediate Evaluation: Karyotyping, hormonal assays, imaging of internal genitalia. Multidisciplinary Team: Involves endocrinologists, geneticists, urologists, psychologists, and ethicists. Parental Counseling: Clear communication about diagnosis, prognosis, and treatment options. Surgical and Hormonal Interventions: Individualized, based on the child’s condition and long-term psychosocial considerations. Ethical Considerations The focus is on ensuring the child’s well-being, minimizing invasive procedures early in life, and promoting informed decision-making as the child matures. Early diagnosis and a family-centered approach are critical in managing DSD in children to optimize both physical and psychological outcomes. ]]>
Disorders of Sex Development (DSD) in Children Disorders of Sex Development (DSD) refer to congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is atypical. These conditions can present in various forms, such as ambiguous genitalia, discrepancies between chromosomal and phenotypic sex, or atypical gonadal development. Classification DSD can be categorized into: 1. 46,XX DSD: Typically involves virilization of genetic females (e.g., congenital adrenal hyperplasia). 2. 46,XY DSD: Typically involves undervirilization of genetic males (e.g., androgen insensitivity syndrome). 3. Sex Chromosome DSD: Includes conditions like Turner syndrome (45,X) and Klinefelter syndrome (47,XXY). Clinical Presentation Ambiguous genitalia at birth (e.g., clitoromegaly, hypospadias, cryptorchidism). Discordance between prenatal sex determination and genital appearance. Delayed or abnormal puberty. Management Immediate Evaluation: Karyotyping, hormonal assays, imaging of internal genitalia. Multidisciplinary Team: Involves endocrinologists, geneticists, urologists, psychologists, and ethicists. Parental Counseling: Clear communication about diagnosis, prognosis, and treatment options. Surgical and Hormonal Interventions: Individualized, based on the child’s condition and long-term psychosocial considerations. Ethical Considerations The focus is on ensuring the child’s well-being, minimizing invasive procedures early in life, and promoting informed decision-making as the child matures. Early diagnosis and a family-centered approach are critical in managing DSD in children to optimize both physical and psychological outcomes. ]]> Fri, 22 Nov 2024 10:37:50 GMT /slideshow/dsd-disorders-of-sexual-development-pptx/273522480 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) DSD ( disorders of sexual development).pptx RAGHUNATHKARMAKER1 Disorders of Sex Development (DSD) in Children Disorders of Sex Development (DSD) refer to congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is atypical. These conditions can present in various forms, such as ambiguous genitalia, discrepancies between chromosomal and phenotypic sex, or atypical gonadal development. Classification DSD can be categorized into: 1. 46,XX DSD: Typically involves virilization of genetic females (e.g., congenital adrenal hyperplasia). 2. 46,XY DSD: Typically involves undervirilization of genetic males (e.g., androgen insensitivity syndrome). 3. Sex Chromosome DSD: Includes conditions like Turner syndrome (45,X) and Klinefelter syndrome (47,XXY). Clinical Presentation Ambiguous genitalia at birth (e.g., clitoromegaly, hypospadias, cryptorchidism). Discordance between prenatal sex determination and genital appearance. Delayed or abnormal puberty. Management Immediate Evaluation: Karyotyping, hormonal assays, imaging of internal genitalia. Multidisciplinary Team: Involves endocrinologists, geneticists, urologists, psychologists, and ethicists. Parental Counseling: Clear communication about diagnosis, prognosis, and treatment options. Surgical and Hormonal Interventions: Individualized, based on the child’s condition and long-term psychosocial considerations. Ethical Considerations The focus is on ensuring the child’s well-being, minimizing invasive procedures early in life, and promoting informed decision-making as the child matures. Early diagnosis and a family-centered approach are critical in managing DSD in children to optimize both physical and psychological outcomes. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/dsddisordersofsexualdevelopment-241122103750-9146407a-thumbnail.jpg?width=120&height=120&fit=bounds" /> Disorders of Sex Development (DSD) in Children Disorders of Sex Development (DSD) refer to congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is atypical. These conditions can present in various forms, such as ambiguous genitalia, discrepancies between chromosomal and phenotypic sex, or atypical gonadal development. Classification DSD can be categorized into: 1. 46,XX DSD: Typically involves virilization of genetic females (e.g., congenital adrenal hyperplasia). 2. 46,XY DSD: Typically involves undervirilization of genetic males (e.g., androgen insensitivity syndrome). 3. Sex Chromosome DSD: Includes conditions like Turner syndrome (45,X) and Klinefelter syndrome (47,XXY). Clinical Presentation Ambiguous genitalia at birth (e.g., clitoromegaly, hypospadias, cryptorchidism). Discordance between prenatal sex determination and genital appearance. Delayed or abnormal puberty. Management Immediate Evaluation: Karyotyping, hormonal assays, imaging of internal genitalia. Multidisciplinary Team: Involves endocrinologists, geneticists, urologists, psychologists, and ethicists. Parental Counseling: Clear communication about diagnosis, prognosis, and treatment options. Surgical and Hormonal Interventions: Individualized, based on the child’s condition and long-term psychosocial considerations. Ethical Considerations The focus is on ensuring the child’s well-being, minimizing invasive procedures early in life, and promoting informed decision-making as the child matures. Early diagnosis and a family-centered approach are critical in managing DSD in children to optimize both physical and psychological outcomes.

DSD ( disorders of sexual development).pptx from RAGHUNATHKARMAKER1

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0 lymphoma Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological featurespptx /slideshow/lymphoma-lymphoma-is-a-type-of-hematologic-malignancy-originating-in-the-lymphatic-system-it-is-broadly-classified-into-hodgkin-lymphoma-hl-and-non-hodgkin-lymphoma-nhl-based-on-histopathological-featurespptx/273522210 lymphoma-241122102547-d086c1dd
Lymphoma: A Long Case Study Introduction Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological features. Lymphoma can manifest with diverse clinical presentations, making it a challenging and critical condition to diagnose and manage. This case study delves into the clinical presentation, diagnostic process, and management of a patient with lymphoma. --- Case Presentation Patient Profile Name: Mr. X Age: 42 years Gender: Male Occupation: Accountant Address: Urban area Chief Complaints Persistent fever for 3 months Painless neck swelling for 2 months Night sweats and weight loss of 8 kg over 3 months History of Present Illness The patient first noticed a painless swelling in the right side of his neck, progressively increasing in size. It was associated with intermittent fever, not responding to over-the-counter medications. He experienced drenching night sweats and a significant loss of appetite. No history of cough, hemoptysis, or contact with tuberculosis patients was noted. Past Medical History No significant past illnesses or surgeries No history of blood transfusions or irradiation Family History No family history of malignancy or hematological disorders Personal and Social History Non-smoker and non-alcoholic Lives in a well-ventilated home; no occupational exposures --- Clinical Examination General Examination Pallor: Present Lymphadenopathy: Enlarged, firm, non-tender nodes in the cervical region B symptoms: Fever, night sweats, weight loss No icterus, cyanosis, clubbing, or edema Systemic Examination Respiratory: Normal breath sounds, no crepitations Cardiovascular: Normal heart sounds Abdomen: No hepatosplenomegaly Neurological: Intact --- Investigations Initial Blood Work Hemoglobin: 9.5 g/dL (anemia) Total Leukocyte Count: 15,000/µL (mild leukocytosis) Platelet Count: Normal ESR: Elevated Specific Tests Peripheral Smear: Revealed mild anemia, no atypical cells Lymph Node Biopsy: Confirmed Hodgkin lymphoma (Reed-Sternberg cells identified) Imaging: Chest X-ray: Mediastinal widening PET-CT: Identified nodal involvement in cervical, mediastinal, and abdominal regions Staging Based on the Ann Arbor classification, the disease was staged as Stage III B (nodal involvement on both sides of the diaphragm with systemic symptoms). --- Management Treatment Protocol 1. Chemotherapy: ABVD regimen (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) administered in 6 cycles. 2. Radiotherapy: Consolidative radiotherapy to involved nodal sites after chemotherapy. 3. Supportive Care: Blood transfusions for anemia Antipyretics and hydration for fever Growth factor support (e.g., G-CSF) Follow-Up Plan Monthly clinical reviews during therapy PET-CT after completing treatment to assess remission status Long-term monitoring for late treat]]>
Lymphoma: A Long Case Study Introduction Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological features. Lymphoma can manifest with diverse clinical presentations, making it a challenging and critical condition to diagnose and manage. This case study delves into the clinical presentation, diagnostic process, and management of a patient with lymphoma. --- Case Presentation Patient Profile Name: Mr. X Age: 42 years Gender: Male Occupation: Accountant Address: Urban area Chief Complaints Persistent fever for 3 months Painless neck swelling for 2 months Night sweats and weight loss of 8 kg over 3 months History of Present Illness The patient first noticed a painless swelling in the right side of his neck, progressively increasing in size. It was associated with intermittent fever, not responding to over-the-counter medications. He experienced drenching night sweats and a significant loss of appetite. No history of cough, hemoptysis, or contact with tuberculosis patients was noted. Past Medical History No significant past illnesses or surgeries No history of blood transfusions or irradiation Family History No family history of malignancy or hematological disorders Personal and Social History Non-smoker and non-alcoholic Lives in a well-ventilated home; no occupational exposures --- Clinical Examination General Examination Pallor: Present Lymphadenopathy: Enlarged, firm, non-tender nodes in the cervical region B symptoms: Fever, night sweats, weight loss No icterus, cyanosis, clubbing, or edema Systemic Examination Respiratory: Normal breath sounds, no crepitations Cardiovascular: Normal heart sounds Abdomen: No hepatosplenomegaly Neurological: Intact --- Investigations Initial Blood Work Hemoglobin: 9.5 g/dL (anemia) Total Leukocyte Count: 15,000/µL (mild leukocytosis) Platelet Count: Normal ESR: Elevated Specific Tests Peripheral Smear: Revealed mild anemia, no atypical cells Lymph Node Biopsy: Confirmed Hodgkin lymphoma (Reed-Sternberg cells identified) Imaging: Chest X-ray: Mediastinal widening PET-CT: Identified nodal involvement in cervical, mediastinal, and abdominal regions Staging Based on the Ann Arbor classification, the disease was staged as Stage III B (nodal involvement on both sides of the diaphragm with systemic symptoms). --- Management Treatment Protocol 1. Chemotherapy: ABVD regimen (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) administered in 6 cycles. 2. Radiotherapy: Consolidative radiotherapy to involved nodal sites after chemotherapy. 3. Supportive Care: Blood transfusions for anemia Antipyretics and hydration for fever Growth factor support (e.g., G-CSF) Follow-Up Plan Monthly clinical reviews during therapy PET-CT after completing treatment to assess remission status Long-term monitoring for late treat]]> Fri, 22 Nov 2024 10:25:47 GMT /slideshow/lymphoma-lymphoma-is-a-type-of-hematologic-malignancy-originating-in-the-lymphatic-system-it-is-broadly-classified-into-hodgkin-lymphoma-hl-and-non-hodgkin-lymphoma-nhl-based-on-histopathological-featurespptx/273522210 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) lymphoma Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological featurespptx RAGHUNATHKARMAKER1 Lymphoma: A Long Case Study Introduction Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological features. Lymphoma can manifest with diverse clinical presentations, making it a challenging and critical condition to diagnose and manage. This case study delves into the clinical presentation, diagnostic process, and management of a patient with lymphoma. --- Case Presentation Patient Profile Name: Mr. X Age: 42 years Gender: Male Occupation: Accountant Address: Urban area Chief Complaints Persistent fever for 3 months Painless neck swelling for 2 months Night sweats and weight loss of 8 kg over 3 months History of Present Illness The patient first noticed a painless swelling in the right side of his neck, progressively increasing in size. It was associated with intermittent fever, not responding to over-the-counter medications. He experienced drenching night sweats and a significant loss of appetite. No history of cough, hemoptysis, or contact with tuberculosis patients was noted. Past Medical History No significant past illnesses or surgeries No history of blood transfusions or irradiation Family History No family history of malignancy or hematological disorders Personal and Social History Non-smoker and non-alcoholic Lives in a well-ventilated home; no occupational exposures --- Clinical Examination General Examination Pallor: Present Lymphadenopathy: Enlarged, firm, non-tender nodes in the cervical region B symptoms: Fever, night sweats, weight loss No icterus, cyanosis, clubbing, or edema Systemic Examination Respiratory: Normal breath sounds, no crepitations Cardiovascular: Normal heart sounds Abdomen: No hepatosplenomegaly Neurological: Intact --- Investigations Initial Blood Work Hemoglobin: 9.5 g/dL (anemia) Total Leukocyte Count: 15,000/µL (mild leukocytosis) Platelet Count: Normal ESR: Elevated Specific Tests Peripheral Smear: Revealed mild anemia, no atypical cells Lymph Node Biopsy: Confirmed Hodgkin lymphoma (Reed-Sternberg cells identified) Imaging: Chest X-ray: Mediastinal widening PET-CT: Identified nodal involvement in cervical, mediastinal, and abdominal regions Staging Based on the Ann Arbor classification, the disease was staged as Stage III B (nodal involvement on both sides of the diaphragm with systemic symptoms). --- Management Treatment Protocol 1. Chemotherapy: ABVD regimen (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) administered in 6 cycles. 2. Radiotherapy: Consolidative radiotherapy to involved nodal sites after chemotherapy. 3. Supportive Care: Blood transfusions for anemia Antipyretics and hydration for fever Growth factor support (e.g., G-CSF) Follow-Up Plan Monthly clinical reviews during therapy PET-CT after completing treatment to assess remission status Long-term monitoring for late treat <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/lymphoma-241122102547-d086c1dd-thumbnail.jpg?width=120&height=120&fit=bounds" /> Lymphoma: A Long Case Study Introduction Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological features. Lymphoma can manifest with diverse clinical presentations, making it a challenging and critical condition to diagnose and manage. This case study delves into the clinical presentation, diagnostic process, and management of a patient with lymphoma. --- Case Presentation Patient Profile Name: Mr. X Age: 42 years Gender: Male Occupation: Accountant Address: Urban area Chief Complaints Persistent fever for 3 months Painless neck swelling for 2 months Night sweats and weight loss of 8 kg over 3 months History of Present Illness The patient first noticed a painless swelling in the right side of his neck, progressively increasing in size. It was associated with intermittent fever, not responding to over-the-counter medications. He experienced drenching night sweats and a significant loss of appetite. No history of cough, hemoptysis, or contact with tuberculosis patients was noted. Past Medical History No significant past illnesses or surgeries No history of blood transfusions or irradiation Family History No family history of malignancy or hematological disorders Personal and Social History Non-smoker and non-alcoholic Lives in a well-ventilated home; no occupational exposures --- Clinical Examination General Examination Pallor: Present Lymphadenopathy: Enlarged, firm, non-tender nodes in the cervical region B symptoms: Fever, night sweats, weight loss No icterus, cyanosis, clubbing, or edema Systemic Examination Respiratory: Normal breath sounds, no crepitations Cardiovascular: Normal heart sounds Abdomen: No hepatosplenomegaly Neurological: Intact --- Investigations Initial Blood Work Hemoglobin: 9.5 g/dL (anemia) Total Leukocyte Count: 15,000/µL (mild leukocytosis) Platelet Count: Normal ESR: Elevated Specific Tests Peripheral Smear: Revealed mild anemia, no atypical cells Lymph Node Biopsy: Confirmed Hodgkin lymphoma (Reed-Sternberg cells identified) Imaging: Chest X-ray: Mediastinal widening PET-CT: Identified nodal involvement in cervical, mediastinal, and abdominal regions Staging Based on the Ann Arbor classification, the disease was staged as Stage III B (nodal involvement on both sides of the diaphragm with systemic symptoms). --- Management Treatment Protocol 1. Chemotherapy: ABVD regimen (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) administered in 6 cycles. 2. Radiotherapy: Consolidative radiotherapy to involved nodal sites after chemotherapy. 3. Supportive Care: Blood transfusions for anemia Antipyretics and hydration for fever Growth factor support (e.g., G-CSF) Follow-Up Plan Monthly clinical reviews during therapy PET-CT after completing treatment to assess remission status Long-term monitoring for late treat

lymphoma Lymphoma is a type of hematologic malignancy originating in the lymphatic system. It is broadly classified into Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) based on histopathological featurespptx from RAGHUNATHKARMAKER1

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0 sacrococcygeal teratoma dr. raghu nath.pptx /slideshow/sacrococcygeal-teratoma-dr-raghu-nath-pptx/270067449 sacrococcygealteratomadr-240704181155-aa0bca38
Saccrococcygeal teratoma, how you will present a long case, paediatric surgery is revolutionary subject in Bangladesh ]]>
Saccrococcygeal teratoma, how you will present a long case, paediatric surgery is revolutionary subject in Bangladesh ]]> Thu, 04 Jul 2024 18:11:55 GMT /slideshow/sacrococcygeal-teratoma-dr-raghu-nath-pptx/270067449 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) sacrococcygeal teratoma dr. raghu nath.pptx RAGHUNATHKARMAKER1 Saccrococcygeal teratoma, how you will present a long case, paediatric surgery is revolutionary subject in Bangladesh <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/sacrococcygealteratomadr-240704181155-aa0bca38-thumbnail.jpg?width=120&height=120&fit=bounds" /> Saccrococcygeal teratoma, how you will present a long case, paediatric surgery is revolutionary subject in Bangladesh

sacrococcygeal teratoma dr. raghu nath.pptx from RAGHUNATHKARMAKER1

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0 all staged complete ARM (raghu).pptx /slideshow/all-staged-complete-arm-raghupptx-259123628/259123628 allstagedcompletearmraghu-230710175051-3a13196a
arm]]>
arm]]> Mon, 10 Jul 2023 17:50:51 GMT /slideshow/all-staged-complete-arm-raghupptx-259123628/259123628 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) all staged complete ARM (raghu).pptx RAGHUNATHKARMAKER1 arm <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/allstagedcompletearmraghu-230710175051-3a13196a-thumbnail.jpg?width=120&height=120&fit=bounds" /> arm

all staged complete ARM (raghu).pptx from RAGHUNATHKARMAKER1

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0 BURN , RAGHU NATH.pptx /slideshow/burn-raghu-nathpptx-259123596/259123596 burnraghunath-230710174727-e1cc7529
BURN]]>
BURN]]> Mon, 10 Jul 2023 17:47:27 GMT /slideshow/burn-raghu-nathpptx-259123596/259123596 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) BURN , RAGHU NATH.pptx RAGHUNATHKARMAKER1 BURN <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/burnraghunath-230710174727-e1cc7529-thumbnail.jpg?width=120&height=120&fit=bounds" /> BURN

BURN , RAGHU NATH.pptx from RAGHUNATHKARMAKER1

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0 Mesenteric and omental cyst.pptx /slideshow/mesenteric-and-omental-cystpptx-259123566/259123566 mesentericandomentalcyst-230710174508-fa4bd172
OMENTAL CYST]]>
OMENTAL CYST]]> Mon, 10 Jul 2023 17:45:07 GMT /slideshow/mesenteric-and-omental-cystpptx-259123566/259123566 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Mesenteric and omental cyst.pptx RAGHUNATHKARMAKER1 OMENTAL CYST <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/mesentericandomentalcyst-230710174508-fa4bd172-thumbnail.jpg?width=120&height=120&fit=bounds" /> OMENTAL CYST

Mesenteric and omental cyst.pptx from RAGHUNATHKARMAKER1

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0 Long case..Renal stone.ppt /slideshow/long-caserenal-stoneppt/259123552 longcase-230710174314-10de04d5
RENAL STONE]]>
RENAL STONE]]> Mon, 10 Jul 2023 17:43:14 GMT /slideshow/long-caserenal-stoneppt/259123552 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Long case..Renal stone.ppt RAGHUNATHKARMAKER1 RENAL STONE <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/longcase-230710174314-10de04d5-thumbnail.jpg?width=120&height=120&fit=bounds" /> RENAL STONE

Long case..Renal stone.ppt from RAGHUNATHKARMAKER1

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0 Long case presentation ( urogenital sinus ).pptx /slideshow/long-case-presentation-urogenital-sinus-pptx/259123541 longcasepresentationurogenitalsinus-230710174205-a438c53a
UROGENITAL SINUS]]>
UROGENITAL SINUS]]> Mon, 10 Jul 2023 17:42:05 GMT /slideshow/long-case-presentation-urogenital-sinus-pptx/259123541 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Long case presentation ( urogenital sinus ).pptx RAGHUNATHKARMAKER1 UROGENITAL SINUS <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/longcasepresentationurogenitalsinus-230710174205-a438c53a-thumbnail.jpg?width=120&height=120&fit=bounds" /> UROGENITAL SINUS

Long case presentation ( urogenital sinus ).pptx from RAGHUNATHKARMAKER1

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0 choledochal cyst.pptx /slideshow/choledochal-cystpptx-259123520/259123520 choledochalcyst-230710174001-603455e5
CYST, CHOLEDOCHAL CYST]]>
CYST, CHOLEDOCHAL CYST]]> Mon, 10 Jul 2023 17:40:01 GMT /slideshow/choledochal-cystpptx-259123520/259123520 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) choledochal cyst.pptx RAGHUNATHKARMAKER1 CYST, CHOLEDOCHAL CYST <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/choledochalcyst-230710174001-603455e5-thumbnail.jpg?width=120&height=120&fit=bounds" /> CYST, CHOLEDOCHAL CYST

choledochal cyst.pptx from RAGHUNATHKARMAKER1

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0 hirschsprung disease.pptx /slideshow/hirschsprung-diseasepptx-259123496/259123496 hirschsprungdisease-230710173707-65d7c623
HD]]>
HD]]> Mon, 10 Jul 2023 17:37:07 GMT /slideshow/hirschsprung-diseasepptx-259123496/259123496 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) hirschsprung disease.pptx RAGHUNATHKARMAKER1 HD <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/hirschsprungdisease-230710173707-65d7c623-thumbnail.jpg?width=120&height=120&fit=bounds" /> HD

hirschsprung disease.pptx from RAGHUNATHKARMAKER1

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0 Dr.neuroblastoma.pptx /slideshow/drneuroblastomapptx/259123475 dr-230710173438-e3096724
neuroblastoma]]>
neuroblastoma]]> Mon, 10 Jul 2023 17:34:38 GMT /slideshow/drneuroblastomapptx/259123475 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Dr.neuroblastoma.pptx RAGHUNATHKARMAKER1 neuroblastoma <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/dr-230710173438-e3096724-thumbnail.jpg?width=120&height=120&fit=bounds" /> neuroblastoma

Dr.neuroblastoma.pptx from RAGHUNATHKARMAKER1

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0 newBorn physiology raghunath.pptx /slideshow/newborn-physiology-raghunathpptx/259123442 newbornphysiologyraghunath-230710173211-23147bff
new born physiology]]>
new born physiology]]> Mon, 10 Jul 2023 17:32:11 GMT /slideshow/newborn-physiology-raghunathpptx/259123442 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) newBorn physiology raghunath.pptx RAGHUNATHKARMAKER1 new born physiology <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/newbornphysiologyraghunath-230710173211-23147bff-thumbnail.jpg?width=120&height=120&fit=bounds" /> new born physiology

newBorn physiology raghunath.pptx from RAGHUNATHKARMAKER1

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0 Raghu nath.pdf /slideshow/raghu-nathpdf/255124962 raghunath-230103161731-4b6d3d09
PREOPERATIVE PREPARATION]]>
PREOPERATIVE PREPARATION]]> Tue, 03 Jan 2023 16:17:31 GMT /slideshow/raghu-nathpdf/255124962 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Raghu nath.pdf RAGHUNATHKARMAKER1 PREOPERATIVE PREPARATION <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/raghunath-230103161731-4b6d3d09-thumbnail.jpg?width=120&height=120&fit=bounds" /> PREOPERATIVE PREPARATION

Raghu nath.pdf from RAGHUNATHKARMAKER1

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0 Portal HTN By Amit.pptx /slideshow/portal-htn-by-amitpptx/255124645 portalhtnbyamit-230103154452-71190aba
PORTAL HYPERTENSION]]>
PORTAL HYPERTENSION]]> Tue, 03 Jan 2023 15:44:52 GMT /slideshow/portal-htn-by-amitpptx/255124645 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Portal HTN By Amit.pptx RAGHUNATHKARMAKER1 PORTAL HYPERTENSION <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/portalhtnbyamit-230103154452-71190aba-thumbnail.jpg?width=120&height=120&fit=bounds" /> PORTAL HYPERTENSION

Portal HTN By Amit.pptx from RAGHUNATHKARMAKER1

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0 Nephroblastoma amit.pptx /slideshow/nephroblastoma-amitpptx/255124624 nephroblastomaamit-230103154333-79a5683c
NEPHROBLASTOMA]]>
NEPHROBLASTOMA]]> Tue, 03 Jan 2023 15:43:33 GMT /slideshow/nephroblastoma-amitpptx/255124624 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Nephroblastoma amit.pptx RAGHUNATHKARMAKER1 NEPHROBLASTOMA <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/nephroblastomaamit-230103154333-79a5683c-thumbnail.jpg?width=120&height=120&fit=bounds" /> NEPHROBLASTOMA

Nephroblastoma amit.pptx from RAGHUNATHKARMAKER1

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0 PRIMARY MANAGEMENT OF TRAUMA.pptx /slideshow/primary-management-of-traumapptx/255124614 primarymanagementoftrauma-230103154210-62c6f247
TRAUMA]]>
TRAUMA]]> Tue, 03 Jan 2023 15:42:10 GMT /slideshow/primary-management-of-traumapptx/255124614 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) PRIMARY MANAGEMENT OF TRAUMA.pptx RAGHUNATHKARMAKER1 TRAUMA <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/primarymanagementoftrauma-230103154210-62c6f247-thumbnail.jpg?width=120&height=120&fit=bounds" /> TRAUMA

PRIMARY MANAGEMENT OF TRAUMA.pptx from RAGHUNATHKARMAKER1

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0 Head injury.pptx /slideshow/head-injurypptx-255124576/255124576 headinjury-230103153827-a9f534c5
HEAD INJURY]]>
HEAD INJURY]]> Tue, 03 Jan 2023 15:38:27 GMT /slideshow/head-injurypptx-255124576/255124576 RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Head injury.pptx RAGHUNATHKARMAKER1 HEAD INJURY <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/headinjury-230103153827-a9f534c5-thumbnail.jpg?width=120&height=120&fit=bounds" /> HEAD INJURY

Head injury.pptx from RAGHUNATHKARMAKER1

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0 Correction Esophageal Atresia & TEF (Raghu).pptx /RAGHUNATHKARMAKER1/correction-esophageal-atresia-tef-raghupptx correctionesophagealatresiatefraghu-230103153716-65d6cadd
ESOPHAGEAL ATRESIA AND TRACHEOSOPHAGEAL FISTULA]]>
ESOPHAGEAL ATRESIA AND TRACHEOSOPHAGEAL FISTULA]]> Tue, 03 Jan 2023 15:37:16 GMT /RAGHUNATHKARMAKER1/correction-esophageal-atresia-tef-raghupptx RAGHUNATHKARMAKER1@slideshare.net(RAGHUNATHKARMAKER1) Correction Esophageal Atresia & TEF (Raghu).pptx RAGHUNATHKARMAKER1 ESOPHAGEAL ATRESIA AND TRACHEOSOPHAGEAL FISTULA <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/correctionesophagealatresiatefraghu-230103153716-65d6cadd-thumbnail.jpg?width=120&height=120&fit=bounds" /> ESOPHAGEAL ATRESIA AND TRACHEOSOPHAGEAL FISTULA

Correction Esophageal Atresia & TEF (Raghu).pptx from RAGHUNATHKARMAKER1

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0 https://public.slidesharecdn.com/v2/images/profile-picture.png https://cdn.slidesharecdn.com/ss_thumbnails/neuroblastomatopicpresentation-241122104958-17210b5c-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/neuroblastoma-in-children-topic-presentation-pptx/273522745 NEUROBLASTOMA in child... https://cdn.slidesharecdn.com/ss_thumbnails/longcasewilmstumorcopy-241122104653-4cf9f975-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/long-case-wilms-tumor-copy-most-common-renal-malignancy-in-children-pptx/273522675 long case,Wilms tumor ... https://cdn.slidesharecdn.com/ss_thumbnails/dsddisordersofsexualdevelopment-241122103750-9146407a-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/dsd-disorders-of-sexual-development-pptx/273522480 DSD ( disorders of sex...