ºÝºÝߣshows by User: WatersChemical / http://www.slideshare.net/images/logo.gif ºÝºÝߣshows by User: WatersChemical / Wed, 09 Mar 2016 16:18:56 GMT ºÝºÝߣShare feed for ºÝºÝߣshows by User: WatersChemical Analysis of Allergens in Perfumes, Cosmetics and Personal Care Products /slideshow/analysis-of-allergens-in-perfumes-cosmetics-and-personal-care-products/59324165 cosmeticallergensupdatefeb2016janecooperv2-160309161856
Jane Cooper, Senior Applications Scientist Separation by UPC2 is an ideal alternative to both HPLC and GC analysis - Ability to run LC and GC amenable compounds in single analysis -Fast 7 minute analysis of the 24 regulated allergens and 6 additional compounds containing: – Different classes of compounds – Different polarities - UC2 with MS detection offers an orthogonal technique, which enables greater selectivity and specificity compared to either HPLC or GC analysis alon - The developed 7 minute UPC2 method, is greater than 6 times faster than existing HPLC and GC]]>

Jane Cooper, Senior Applications Scientist Separation by UPC2 is an ideal alternative to both HPLC and GC analysis - Ability to run LC and GC amenable compounds in single analysis -Fast 7 minute analysis of the 24 regulated allergens and 6 additional compounds containing: – Different classes of compounds – Different polarities - UC2 with MS detection offers an orthogonal technique, which enables greater selectivity and specificity compared to either HPLC or GC analysis alon - The developed 7 minute UPC2 method, is greater than 6 times faster than existing HPLC and GC]]>
Wed, 09 Mar 2016 16:18:56 GMT /slideshow/analysis-of-allergens-in-perfumes-cosmetics-and-personal-care-products/59324165 WatersChemical@slideshare.net(WatersChemical) Analysis of Allergens in Perfumes, Cosmetics and Personal Care Products WatersChemical Jane Cooper, Senior Applications Scientist Separation by UPC2 is an ideal alternative to both HPLC and GC analysis - Ability to run LC and GC amenable compounds in single analysis -Fast 7 minute analysis of the 24 regulated allergens and 6 additional compounds containing: – Different classes of compounds – Different polarities - UC2 with MS detection offers an orthogonal technique, which enables greater selectivity and specificity compared to either HPLC or GC analysis alon - The developed 7 minute UPC2 method, is greater than 6 times faster than existing HPLC and GC <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/cosmeticallergensupdatefeb2016janecooperv2-160309161856-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Jane Cooper, Senior Applications Scientist Separation by UPC2 is an ideal alternative to both HPLC and GC analysis - Ability to run LC and GC amenable compounds in single analysis -Fast 7 minute analysis of the 24 regulated allergens and 6 additional compounds containing: – Different classes of compounds – Different polarities - UC2 with MS detection offers an orthogonal technique, which enables greater selectivity and specificity compared to either HPLC or GC analysis alon - The developed 7 minute UPC2 method, is greater than 6 times faster than existing HPLC and GC
Analysis of Allergens in Perfumes, Cosmetics and Personal Care Products from Waters Corporation - Chemical Materials
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Mass Detection for the Cosmetics Industry /slideshow/mass-detection-for-the-cosmetics-industry/59323830 massdetectionforthecosmeticsindustryjanecooper-160309161209
Jane Cooper, Senior Applications Scientist, Waters Corporation. ï‚¡ Method development Aim: One peak = one compound Detect coelutions and peaks missed by optical detection Track peaks more effectively Sample profiling Aim: Identify components and quantify Process complex matrices and low level target compounds Improved selectivity, more sensitivity ï‚¡ Synthetic chemistry Aim: Confirm product identity Improve turnaround of results Improve information available on impurities ï‚¡ Purification Aim: Isolate pure compound Collect fewer fractions with increased confidence]]>

Jane Cooper, Senior Applications Scientist, Waters Corporation. ï‚¡ Method development Aim: One peak = one compound Detect coelutions and peaks missed by optical detection Track peaks more effectively Sample profiling Aim: Identify components and quantify Process complex matrices and low level target compounds Improved selectivity, more sensitivity ï‚¡ Synthetic chemistry Aim: Confirm product identity Improve turnaround of results Improve information available on impurities ï‚¡ Purification Aim: Isolate pure compound Collect fewer fractions with increased confidence]]>
Wed, 09 Mar 2016 16:12:08 GMT /slideshow/mass-detection-for-the-cosmetics-industry/59323830 WatersChemical@slideshare.net(WatersChemical) Mass Detection for the Cosmetics Industry WatersChemical Jane Cooper, Senior Applications Scientist, Waters Corporation. ï‚¡ Method development Aim: One peak = one compound Detect coelutions and peaks missed by optical detection Track peaks more effectively Sample profiling Aim: Identify components and quantify Process complex matrices and low level target compounds Improved selectivity, more sensitivity ï‚¡ Synthetic chemistry Aim: Confirm product identity Improve turnaround of results Improve information available on impurities ï‚¡ Purification Aim: Isolate pure compound Collect fewer fractions with increased confidence <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/massdetectionforthecosmeticsindustryjanecooper-160309161209-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Jane Cooper, Senior Applications Scientist, Waters Corporation. ï‚¡ Method development Aim: One peak = one compound Detect coelutions and peaks missed by optical detection Track peaks more effectively Sample profiling Aim: Identify components and quantify Process complex matrices and low level target compounds Improved selectivity, more sensitivity ï‚¡ Synthetic chemistry Aim: Confirm product identity Improve turnaround of results Improve information available on impurities ï‚¡ Purification Aim: Isolate pure compound Collect fewer fractions with increased confidence
Mass Detection for the Cosmetics Industry from Waters Corporation - Chemical Materials
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Latest Advancements for Developing Next Generation Agrochemicals /slideshow/latest-advancements-for-developing-next-generation-agrochemicals/58480535 agrochemslidesharev3-160219203728
Waters analytical technologies enable laboratories to generate more information, complete analyses more rapidly and reduce overall costs throughout key steps in the agrochemical development workflow - including Synthetic Chemistry, Purification, Formulation, Trace Detection, Metabolite ID.]]>

Waters analytical technologies enable laboratories to generate more information, complete analyses more rapidly and reduce overall costs throughout key steps in the agrochemical development workflow - including Synthetic Chemistry, Purification, Formulation, Trace Detection, Metabolite ID.]]>
Fri, 19 Feb 2016 20:37:28 GMT /slideshow/latest-advancements-for-developing-next-generation-agrochemicals/58480535 WatersChemical@slideshare.net(WatersChemical) Latest Advancements for Developing Next Generation Agrochemicals WatersChemical Waters analytical technologies enable laboratories to generate more information, complete analyses more rapidly and reduce overall costs throughout key steps in the agrochemical development workflow - including Synthetic Chemistry, Purification, Formulation, Trace Detection, Metabolite ID. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/agrochemslidesharev3-160219203728-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Waters analytical technologies enable laboratories to generate more information, complete analyses more rapidly and reduce overall costs throughout key steps in the agrochemical development workflow - including Synthetic Chemistry, Purification, Formulation, Trace Detection, Metabolite ID.
Latest Advancements for Developing Next Generation Agrochemicals from Waters Corporation - Chemical Materials
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Rapid analysis of polymers and petroleum by Ion-mobility mass spectrometry /slideshow/carlos-apac-ets-14jul2015presentation-waters-20151-50746725/50746725 carlosapacets14jul2015presentationwaters2015-150721072740-lva1-app6892
Carlos Afonso, Université de Rouen, Laboratoire COBRA, Plateau technique C2iorga In this presentation, Carlos Afonso describes the analysis of polymers and petroleum by ion mobility mass spectrometry and utilises novel sample introduction techniques such as the Atmospheric Solids Analysis Probe (ASAP).]]>

Carlos Afonso, Université de Rouen, Laboratoire COBRA, Plateau technique C2iorga In this presentation, Carlos Afonso describes the analysis of polymers and petroleum by ion mobility mass spectrometry and utilises novel sample introduction techniques such as the Atmospheric Solids Analysis Probe (ASAP).]]>
Tue, 21 Jul 2015 07:27:40 GMT /slideshow/carlos-apac-ets-14jul2015presentation-waters-20151-50746725/50746725 WatersChemical@slideshare.net(WatersChemical) Rapid analysis of polymers and petroleum by Ion-mobility mass spectrometry WatersChemical Carlos Afonso, Université de Rouen, Laboratoire COBRA, Plateau technique C2iorga In this presentation, Carlos Afonso describes the analysis of polymers and petroleum by ion mobility mass spectrometry and utilises novel sample introduction techniques such as the Atmospheric Solids Analysis Probe (ASAP). <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/carlosapacets14jul2015presentationwaters2015-150721072740-lva1-app6892-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Carlos Afonso, Université de Rouen, Laboratoire COBRA, Plateau technique C2iorga In this presentation, Carlos Afonso describes the analysis of polymers and petroleum by ion mobility mass spectrometry and utilises novel sample introduction techniques such as the Atmospheric Solids Analysis Probe (ASAP).
Rapid analysis of polymers and petroleum by Ion-mobility mass spectrometry from Waters Corporation - Chemical Materials
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APCI and APPI GC/MSMS for Characterization of the Macondo Wellhead Crude Oil and the Oil Spill /slideshow/apci-and-appigcmsms-for-characterization-of-the-macondo-wellhead-crude-oil-and-the-oil-spill/49993971 250pm-chem-materials-vladislav-lobodin-150630082810-lva1-app6892
Vlad Lobodin, National High Magnetic Field Laboratory & Future Fuels Institute, Florida State University, Tallahassee, Florida - discusses advanced mass spectrometry techniques for the characterization of crude oil.]]>

Vlad Lobodin, National High Magnetic Field Laboratory & Future Fuels Institute, Florida State University, Tallahassee, Florida - discusses advanced mass spectrometry techniques for the characterization of crude oil.]]>
Tue, 30 Jun 2015 08:28:10 GMT /slideshow/apci-and-appigcmsms-for-characterization-of-the-macondo-wellhead-crude-oil-and-the-oil-spill/49993971 WatersChemical@slideshare.net(WatersChemical) APCI and APPI GC/MSMS for Characterization of the Macondo Wellhead Crude Oil and the Oil Spill WatersChemical Vlad Lobodin, National High Magnetic Field Laboratory & Future Fuels Institute, Florida State University, Tallahassee, Florida - discusses advanced mass spectrometry techniques for the characterization of crude oil. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/250pm-chem-materials-vladislav-lobodin-150630082810-lva1-app6892-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Vlad Lobodin, National High Magnetic Field Laboratory &amp; Future Fuels Institute, Florida State University, Tallahassee, Florida - discusses advanced mass spectrometry techniques for the characterization of crude oil.
APCI and APPI GC/MSMS for Characterization of the Macondo Wellhead Crude Oil and the Oil Spill from Waters Corporation - Chemical Materials
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Harnessing the power of CCS for routine screening applications on the UNIFI informatics platform /WatersChemical/harnessing-the-power-of-ccs-for-routine-screening-applications-on-the-unifi-informatics-platform chem-materials-cristina-nerin-150629103858-lva1-app6892
Professor Cristina Nerin. Professor of Analytical Chemistry. University of Zaragoza, Spain discusses the benefits of Collisional Cross Section measurements in Ion Mobility for the confirmation of food contaminant in packaging.]]>

Professor Cristina Nerin. Professor of Analytical Chemistry. University of Zaragoza, Spain discusses the benefits of Collisional Cross Section measurements in Ion Mobility for the confirmation of food contaminant in packaging.]]>
Mon, 29 Jun 2015 10:38:58 GMT /WatersChemical/harnessing-the-power-of-ccs-for-routine-screening-applications-on-the-unifi-informatics-platform WatersChemical@slideshare.net(WatersChemical) Harnessing the power of CCS for routine screening applications on the UNIFI informatics platform WatersChemical Professor Cristina Nerin. Professor of Analytical Chemistry. University of Zaragoza, Spain discusses the benefits of Collisional Cross Section measurements in Ion Mobility for the confirmation of food contaminant in packaging. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/chem-materials-cristina-nerin-150629103858-lva1-app6892-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Professor Cristina Nerin. Professor of Analytical Chemistry. University of Zaragoza, Spain discusses the benefits of Collisional Cross Section measurements in Ion Mobility for the confirmation of food contaminant in packaging.
Harnessing the power of CCS for routine screening applications on the UNIFI informatics platform from Waters Corporation - Chemical Materials
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APGC-MS, ASAP-MS, and MAI-MS: Expanding the Horizons of API-MS /slideshow/150-pm-chemical-materialscharles-mcewen/49870505 150pm-chemicalmaterials-charlesmcewen-150626102043-lva1-app6891
Horning’s group in the 1970’s developed atmospheric pressure ionization (API) mass spectrometry (MS), but it was electrospray ionization that drove the commercialization of API-MS as a liquid introduction technology. The utility of gaseous introduction of volatile compounds into an API source and new developments in GC-API/MS and ASAP-MS will be discussed along with the newly discovered matrix-assisted ionization technology that allows ionization of low and high mass compounds on API instruments without use of a laser, high voltage, or even heat.]]>

Horning’s group in the 1970’s developed atmospheric pressure ionization (API) mass spectrometry (MS), but it was electrospray ionization that drove the commercialization of API-MS as a liquid introduction technology. The utility of gaseous introduction of volatile compounds into an API source and new developments in GC-API/MS and ASAP-MS will be discussed along with the newly discovered matrix-assisted ionization technology that allows ionization of low and high mass compounds on API instruments without use of a laser, high voltage, or even heat.]]>
Fri, 26 Jun 2015 10:20:43 GMT /slideshow/150-pm-chemical-materialscharles-mcewen/49870505 WatersChemical@slideshare.net(WatersChemical) APGC-MS, ASAP-MS, and MAI-MS: Expanding the Horizons of API-MS WatersChemical Horning’s group in the 1970’s developed atmospheric pressure ionization (API) mass spectrometry (MS), but it was electrospray ionization that drove the commercialization of API-MS as a liquid introduction technology. The utility of gaseous introduction of volatile compounds into an API source and new developments in GC-API/MS and ASAP-MS will be discussed along with the newly discovered matrix-assisted ionization technology that allows ionization of low and high mass compounds on API instruments without use of a laser, high voltage, or even heat. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/150pm-chemicalmaterials-charlesmcewen-150626102043-lva1-app6891-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Horning’s group in the 1970’s developed atmospheric pressure ionization (API) mass spectrometry (MS), but it was electrospray ionization that drove the commercialization of API-MS as a liquid introduction technology. The utility of gaseous introduction of volatile compounds into an API source and new developments in GC-API/MS and ASAP-MS will be discussed along with the newly discovered matrix-assisted ionization technology that allows ionization of low and high mass compounds on API instruments without use of a laser, high voltage, or even heat.
APGC-MS, ASAP-MS, and MAI-MS: Expanding the Horizons of API-MS from Waters Corporation - Chemical Materials
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Enhancing separations performance for chemicals and polymers presentation /WatersChemical/enhancing-separations-performance-for-chemicals-and-polymers-presentation enhancingseparationsperformanceforchemicalsandpolymerspresentation-150312083132-conversion-gate01
This presentation will provide an introduction to the technology and benefits of Waters ACQUITY Ultra Performance Convergence Chromatography system (UPC2) and illustrate how it can impact the analysis of chemicals and polymers.]]>

This presentation will provide an introduction to the technology and benefits of Waters ACQUITY Ultra Performance Convergence Chromatography system (UPC2) and illustrate how it can impact the analysis of chemicals and polymers.]]>
Thu, 12 Mar 2015 08:31:32 GMT /WatersChemical/enhancing-separations-performance-for-chemicals-and-polymers-presentation WatersChemical@slideshare.net(WatersChemical) Enhancing separations performance for chemicals and polymers presentation WatersChemical This presentation will provide an introduction to the technology and benefits of Waters ACQUITY Ultra Performance Convergence Chromatography system (UPC2) and illustrate how it can impact the analysis of chemicals and polymers. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/enhancingseparationsperformanceforchemicalsandpolymerspresentation-150312083132-conversion-gate01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> This presentation will provide an introduction to the technology and benefits of Waters ACQUITY Ultra Performance Convergence Chromatography system (UPC2) and illustrate how it can impact the analysis of chemicals and polymers.
Enhancing separations performance for chemicals and polymers presentation from Waters Corporation - Chemical Materials
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Ion mobility & PetroOrg software : Novel techniques for petroleomics investigations /slideshow/ion-mobility-petro-org-software-novel-techniques-for-petroleomics-investigations/44644453 ionmobilitypetroorgsoftware-noveltechniquesforpetroleomicsinvestigations-150213091811-conversion-gate02
Ion mobility- mass spectrometry can help to offer an additional orthogonal dimension of separation, and can help to deconvolute isomeric species in the ion mobility dimension, which, in turn, helps to simplify the analysis of these highly complex samples, and map the compositional space of petroleum samples, and can also characterise the shapes and sizes, or collisional cross sections, of molecules of interest. The most important component of this work was the development of novel software that helps the user to visualise, interact with, and process ion mobility data – so, for the first time, we are able to utilise the ion mobility dimension in comprehensive petroleomics analyses.]]>

Ion mobility- mass spectrometry can help to offer an additional orthogonal dimension of separation, and can help to deconvolute isomeric species in the ion mobility dimension, which, in turn, helps to simplify the analysis of these highly complex samples, and map the compositional space of petroleum samples, and can also characterise the shapes and sizes, or collisional cross sections, of molecules of interest. The most important component of this work was the development of novel software that helps the user to visualise, interact with, and process ion mobility data – so, for the first time, we are able to utilise the ion mobility dimension in comprehensive petroleomics analyses.]]>
Fri, 13 Feb 2015 09:18:11 GMT /slideshow/ion-mobility-petro-org-software-novel-techniques-for-petroleomics-investigations/44644453 WatersChemical@slideshare.net(WatersChemical) Ion mobility & PetroOrg software : Novel techniques for petroleomics investigations WatersChemical Ion mobility- mass spectrometry can help to offer an additional orthogonal dimension of separation, and can help to deconvolute isomeric species in the ion mobility dimension, which, in turn, helps to simplify the analysis of these highly complex samples, and map the compositional space of petroleum samples, and can also characterise the shapes and sizes, or collisional cross sections, of molecules of interest. The most important component of this work was the development of novel software that helps the user to visualise, interact with, and process ion mobility data – so, for the first time, we are able to utilise the ion mobility dimension in comprehensive petroleomics analyses. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/ionmobilitypetroorgsoftware-noveltechniquesforpetroleomicsinvestigations-150213091811-conversion-gate02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Ion mobility- mass spectrometry can help to offer an additional orthogonal dimension of separation, and can help to deconvolute isomeric species in the ion mobility dimension, which, in turn, helps to simplify the analysis of these highly complex samples, and map the compositional space of petroleum samples, and can also characterise the shapes and sizes, or collisional cross sections, of molecules of interest. The most important component of this work was the development of novel software that helps the user to visualise, interact with, and process ion mobility data – so, for the first time, we are able to utilise the ion mobility dimension in comprehensive petroleomics analyses.
Ion mobility & PetroOrg software : Novel techniques for petroleomics investigations from Waters Corporation - Chemical Materials
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Hyphenating Convergence Chromatography with UV and MS Detection for Compositional, Impurity and Degradation Analysis of High Performance Electronic Materials /slideshow/emsf-jane-cooper-may-2014b/43660204 emsfjanecoopermay2014b-150119074655-conversion-gate02
Convergence Chromatography (CC) is a separation technique that uses carbon dioxide as the primary mobile phase, with a co-solvent such as acetonitrile to give similar selectivity as normal phase LC. Various detection methods can be used with CC including UV and Evaporative Light Scattering Detection (ELSD), but there is also the option of easily and quickly interfacing Convergence Chromatography with Mass Spectrometry (MS) detection. The additional option to add a solvent via a makeup pump to the flow prior to MS detection can be used to provide greater solvating powers, to enhance the selectivity and sensitivity of MS detection, and also to influence ionization. When using electrospray ionization (ESI) the addition of a protonation source such as formic acid to the makeup solvent can be used to enhance ionization and increase sensitivity. In atmospheric pressure photo ionization (APPI), the addition of a dopant such as toluene to the makeup solvent can enable and enhance ionization. Whereas when using atmospheric pressure chemical ionization (APCI), the solvent present, from both the co-solvent and the makeup solvents, acts as chemical ionization reagent gas in order to ionize the sample.]]>

Convergence Chromatography (CC) is a separation technique that uses carbon dioxide as the primary mobile phase, with a co-solvent such as acetonitrile to give similar selectivity as normal phase LC. Various detection methods can be used with CC including UV and Evaporative Light Scattering Detection (ELSD), but there is also the option of easily and quickly interfacing Convergence Chromatography with Mass Spectrometry (MS) detection. The additional option to add a solvent via a makeup pump to the flow prior to MS detection can be used to provide greater solvating powers, to enhance the selectivity and sensitivity of MS detection, and also to influence ionization. When using electrospray ionization (ESI) the addition of a protonation source such as formic acid to the makeup solvent can be used to enhance ionization and increase sensitivity. In atmospheric pressure photo ionization (APPI), the addition of a dopant such as toluene to the makeup solvent can enable and enhance ionization. Whereas when using atmospheric pressure chemical ionization (APCI), the solvent present, from both the co-solvent and the makeup solvents, acts as chemical ionization reagent gas in order to ionize the sample.]]>
Mon, 19 Jan 2015 07:46:55 GMT /slideshow/emsf-jane-cooper-may-2014b/43660204 WatersChemical@slideshare.net(WatersChemical) Hyphenating Convergence Chromatography with UV and MS Detection for Compositional, Impurity and Degradation Analysis of High Performance Electronic Materials WatersChemical Convergence Chromatography (CC) is a separation technique that uses carbon dioxide as the primary mobile phase, with a co-solvent such as acetonitrile to give similar selectivity as normal phase LC. Various detection methods can be used with CC including UV and Evaporative Light Scattering Detection (ELSD), but there is also the option of easily and quickly interfacing Convergence Chromatography with Mass Spectrometry (MS) detection. The additional option to add a solvent via a makeup pump to the flow prior to MS detection can be used to provide greater solvating powers, to enhance the selectivity and sensitivity of MS detection, and also to influence ionization. When using electrospray ionization (ESI) the addition of a protonation source such as formic acid to the makeup solvent can be used to enhance ionization and increase sensitivity. In atmospheric pressure photo ionization (APPI), the addition of a dopant such as toluene to the makeup solvent can enable and enhance ionization. Whereas when using atmospheric pressure chemical ionization (APCI), the solvent present, from both the co-solvent and the makeup solvents, acts as chemical ionization reagent gas in order to ionize the sample. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/emsfjanecoopermay2014b-150119074655-conversion-gate02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Convergence Chromatography (CC) is a separation technique that uses carbon dioxide as the primary mobile phase, with a co-solvent such as acetonitrile to give similar selectivity as normal phase LC. Various detection methods can be used with CC including UV and Evaporative Light Scattering Detection (ELSD), but there is also the option of easily and quickly interfacing Convergence Chromatography with Mass Spectrometry (MS) detection. The additional option to add a solvent via a makeup pump to the flow prior to MS detection can be used to provide greater solvating powers, to enhance the selectivity and sensitivity of MS detection, and also to influence ionization. When using electrospray ionization (ESI) the addition of a protonation source such as formic acid to the makeup solvent can be used to enhance ionization and increase sensitivity. In atmospheric pressure photo ionization (APPI), the addition of a dopant such as toluene to the makeup solvent can enable and enhance ionization. Whereas when using atmospheric pressure chemical ionization (APCI), the solvent present, from both the co-solvent and the makeup solvents, acts as chemical ionization reagent gas in order to ionize the sample.
Hyphenating Convergence Chromatography with UV and MS Detection for Compositional, Impurity and Degradation Analysis of High Performance Electronic Materials from Waters Corporation - Chemical Materials
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Source, age, maturity and alteration characteristics of oil reservoirs using APGC MS/MS /slideshow/source-age-maturity-and-alteration-characteristics-of-oil-reservoirs-using-apgc-ms-ms-analysis-of-oil-biomarkers-present/43659647 sourceagematurityandalterationcharacteristicsofoilreservoirsusingapgcmsmsanalysisofoilbiomarkerspres-150119073014-conversion-gate02
APGC is a soft ionization technique which produces lower levels of fragmentation compared to traditional EI. Working in dry conditions, APGC typically produces spectra with strong radical cation molecular ions that facilitates the direct comparison of historic, archival EI data from many different sources. The abundant nature of these ions makes it possible to generate specific and sensitive MRM transitions for petroleum biomarkers which provide information on the biological source of the oil, the environment in which the parent organic matter was deposited, and the thermal history of the buried organic matter. Knowledge of these properties is especially useful in upstream applications and is ultimately linked to the economic productivity from a particular geological location. The universal ionization source offered on all Waters instrumentation facilitates the quick and simple coupling of APGC, UPLC or UPC2 on a single MS platform. Coupled with Xevo TQ-S, APGC enables low-level quantification of petroleum biomarkers that have proved challenging to analyze using GC-MS systems, allowing unambiguous confirmation of the deposition environment from which the oil originates.]]>

APGC is a soft ionization technique which produces lower levels of fragmentation compared to traditional EI. Working in dry conditions, APGC typically produces spectra with strong radical cation molecular ions that facilitates the direct comparison of historic, archival EI data from many different sources. The abundant nature of these ions makes it possible to generate specific and sensitive MRM transitions for petroleum biomarkers which provide information on the biological source of the oil, the environment in which the parent organic matter was deposited, and the thermal history of the buried organic matter. Knowledge of these properties is especially useful in upstream applications and is ultimately linked to the economic productivity from a particular geological location. The universal ionization source offered on all Waters instrumentation facilitates the quick and simple coupling of APGC, UPLC or UPC2 on a single MS platform. Coupled with Xevo TQ-S, APGC enables low-level quantification of petroleum biomarkers that have proved challenging to analyze using GC-MS systems, allowing unambiguous confirmation of the deposition environment from which the oil originates.]]>
Mon, 19 Jan 2015 07:30:14 GMT /slideshow/source-age-maturity-and-alteration-characteristics-of-oil-reservoirs-using-apgc-ms-ms-analysis-of-oil-biomarkers-present/43659647 WatersChemical@slideshare.net(WatersChemical) Source, age, maturity and alteration characteristics of oil reservoirs using APGC MS/MS WatersChemical APGC is a soft ionization technique which produces lower levels of fragmentation compared to traditional EI. Working in dry conditions, APGC typically produces spectra with strong radical cation molecular ions that facilitates the direct comparison of historic, archival EI data from many different sources. The abundant nature of these ions makes it possible to generate specific and sensitive MRM transitions for petroleum biomarkers which provide information on the biological source of the oil, the environment in which the parent organic matter was deposited, and the thermal history of the buried organic matter. Knowledge of these properties is especially useful in upstream applications and is ultimately linked to the economic productivity from a particular geological location. The universal ionization source offered on all Waters instrumentation facilitates the quick and simple coupling of APGC, UPLC or UPC2 on a single MS platform. Coupled with Xevo TQ-S, APGC enables low-level quantification of petroleum biomarkers that have proved challenging to analyze using GC-MS systems, allowing unambiguous confirmation of the deposition environment from which the oil originates. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/sourceagematurityandalterationcharacteristicsofoilreservoirsusingapgcmsmsanalysisofoilbiomarkerspres-150119073014-conversion-gate02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> APGC is a soft ionization technique which produces lower levels of fragmentation compared to traditional EI. Working in dry conditions, APGC typically produces spectra with strong radical cation molecular ions that facilitates the direct comparison of historic, archival EI data from many different sources. The abundant nature of these ions makes it possible to generate specific and sensitive MRM transitions for petroleum biomarkers which provide information on the biological source of the oil, the environment in which the parent organic matter was deposited, and the thermal history of the buried organic matter. Knowledge of these properties is especially useful in upstream applications and is ultimately linked to the economic productivity from a particular geological location. The universal ionization source offered on all Waters instrumentation facilitates the quick and simple coupling of APGC, UPLC or UPC2 on a single MS platform. Coupled with Xevo TQ-S, APGC enables low-level quantification of petroleum biomarkers that have proved challenging to analyze using GC-MS systems, allowing unambiguous confirmation of the deposition environment from which the oil originates.
Source, age, maturity and alteration characteristics of oil reservoirs using APGC MS/MS from Waters Corporation - Chemical Materials
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Ion Mobility Petroleomics: Towards Isomeric Compositional Space Elucidation via New Software and Methods /slideshow/asms-2014-oral-presentation-woa-250pmrichespetroleum-ims-for-slideshare/43509405 asms2014oralpresentationwoa2-50pmrichespetroleumimsforslideshare-150114092329-conversion-gate02
Petroleum is undoubtedly the most complex natural mixture known, and its myriad chemical components offer an extraordinary challenge for even the most advanced analytical platforms. Since the introduction of Petroleomic methodologies over a decade ago, a more complete, molecular-level understanding of petroleum has begun to emerge. The use of high resolving power mass spectrometers has led the charge, but new technologies are required for isomer elucidation. Thus, ion mobility with mass spectrometry provides a much-needed structural component to the already complex world of petroleum compositional analysis: the potential for isomer resolution. In this work, we introduce new software (PetroOrg-Software ©) and methodologies that reveal crude oil composition, at the isomeric level, in an automated and chemically intelligent way.]]>

Petroleum is undoubtedly the most complex natural mixture known, and its myriad chemical components offer an extraordinary challenge for even the most advanced analytical platforms. Since the introduction of Petroleomic methodologies over a decade ago, a more complete, molecular-level understanding of petroleum has begun to emerge. The use of high resolving power mass spectrometers has led the charge, but new technologies are required for isomer elucidation. Thus, ion mobility with mass spectrometry provides a much-needed structural component to the already complex world of petroleum compositional analysis: the potential for isomer resolution. In this work, we introduce new software (PetroOrg-Software ©) and methodologies that reveal crude oil composition, at the isomeric level, in an automated and chemically intelligent way.]]>
Wed, 14 Jan 2015 09:23:29 GMT /slideshow/asms-2014-oral-presentation-woa-250pmrichespetroleum-ims-for-slideshare/43509405 WatersChemical@slideshare.net(WatersChemical) Ion Mobility Petroleomics: Towards Isomeric Compositional Space Elucidation via New Software and Methods WatersChemical Petroleum is undoubtedly the most complex natural mixture known, and its myriad chemical components offer an extraordinary challenge for even the most advanced analytical platforms. Since the introduction of Petroleomic methodologies over a decade ago, a more complete, molecular-level understanding of petroleum has begun to emerge. The use of high resolving power mass spectrometers has led the charge, but new technologies are required for isomer elucidation. Thus, ion mobility with mass spectrometry provides a much-needed structural component to the already complex world of petroleum compositional analysis: the potential for isomer resolution. In this work, we introduce new software (PetroOrg-Software ©) and methodologies that reveal crude oil composition, at the isomeric level, in an automated and chemically intelligent way. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/asms2014oralpresentationwoa2-50pmrichespetroleumimsforslideshare-150114092329-conversion-gate02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Petroleum is undoubtedly the most complex natural mixture known, and its myriad chemical components offer an extraordinary challenge for even the most advanced analytical platforms. Since the introduction of Petroleomic methodologies over a decade ago, a more complete, molecular-level understanding of petroleum has begun to emerge. The use of high resolving power mass spectrometers has led the charge, but new technologies are required for isomer elucidation. Thus, ion mobility with mass spectrometry provides a much-needed structural component to the already complex world of petroleum compositional analysis: the potential for isomer resolution. In this work, we introduce new software (PetroOrg-Software ©) and methodologies that reveal crude oil composition, at the isomeric level, in an automated and chemically intelligent way.
Ion Mobility Petroleomics: Towards Isomeric Compositional Space Elucidation via New Software and Methods from Waters Corporation - Chemical Materials
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50 years of size exclusion chromatography /slideshow/50-years-of-size-exclusion-chromatography/43419836 50yearsofsizeexclusionchromatographyseceposter-150112035803-conversion-gate01
This presentation discusses the history of size exclusion chromatography from gel permeation to modern day columns, and introduces the next evolution in polymer chromatography, the ACQUITY Advanced Polymer Chromatography system.]]>

This presentation discusses the history of size exclusion chromatography from gel permeation to modern day columns, and introduces the next evolution in polymer chromatography, the ACQUITY Advanced Polymer Chromatography system.]]>
Mon, 12 Jan 2015 03:58:03 GMT /slideshow/50-years-of-size-exclusion-chromatography/43419836 WatersChemical@slideshare.net(WatersChemical) 50 years of size exclusion chromatography WatersChemical This presentation discusses the history of size exclusion chromatography from gel permeation to modern day columns, and introduces the next evolution in polymer chromatography, the ACQUITY Advanced Polymer Chromatography system. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/50yearsofsizeexclusionchromatographyseceposter-150112035803-conversion-gate01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> This presentation discusses the history of size exclusion chromatography from gel permeation to modern day columns, and introduces the next evolution in polymer chromatography, the ACQUITY Advanced Polymer Chromatography system.
50 years of size exclusion chromatography from Waters Corporation - Chemical Materials
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PetroOrg - Waters and Omics LLC collaborate to unlock Petroleomics /slideshow/petroorg/43318444 00petroorgcustomersummaryv3-150108073540-conversion-gate01
Classifying Petroleum Samples with Waters SYNAPT HDMS and Omics LLC PetroOrg Petroleomics Software Combines the value of Ion Mobility Mass Spectrometry (IM-MS) and accurate mass information with petroleomics data processing to easily characterize petroleum chemical composition. http://www.waters.com/waters/en_US/Petroleomics-Analysis-Solution/nav.htm?cid=134802174&bcid=134528340]]>

Classifying Petroleum Samples with Waters SYNAPT HDMS and Omics LLC PetroOrg Petroleomics Software Combines the value of Ion Mobility Mass Spectrometry (IM-MS) and accurate mass information with petroleomics data processing to easily characterize petroleum chemical composition. http://www.waters.com/waters/en_US/Petroleomics-Analysis-Solution/nav.htm?cid=134802174&bcid=134528340]]>
Thu, 08 Jan 2015 07:35:40 GMT /slideshow/petroorg/43318444 WatersChemical@slideshare.net(WatersChemical) PetroOrg - Waters and Omics LLC collaborate to unlock Petroleomics WatersChemical Classifying Petroleum Samples with Waters SYNAPT HDMS and Omics LLC PetroOrg Petroleomics Software Combines the value of Ion Mobility Mass Spectrometry (IM-MS) and accurate mass information with petroleomics data processing to easily characterize petroleum chemical composition. http://www.waters.com/waters/en_US/Petroleomics-Analysis-Solution/nav.htm?cid=134802174&bcid=134528340 <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/00petroorgcustomersummaryv3-150108073540-conversion-gate01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Classifying Petroleum Samples with Waters SYNAPT HDMS and Omics LLC PetroOrg Petroleomics Software Combines the value of Ion Mobility Mass Spectrometry (IM-MS) and accurate mass information with petroleomics data processing to easily characterize petroleum chemical composition. http://www.waters.com/waters/en_US/Petroleomics-Analysis-Solution/nav.htm?cid=134802174&amp;bcid=134528340
PetroOrg - Waters and Omics LLC collaborate to unlock Petroleomics from Waters Corporation - Chemical Materials
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Routine impurity analysis with UPLC/MS and UPC2/MS /slideshow/routine-impurity-analysis-with-uplcms-and-upc2ms/43315081 anon-routineimpurityanalysiswithuplcmsandupc2msjanecooper-150108054920-conversion-gate01
Fast, selective, and sensitive methods can be developed for the analysis of impurities ï‚¡ Offering many business benefits using UPLC and UPC2 Increase in sample throughput Reduction in toxic solvent usage ï‚¡ Using mass spectral detection over UV detection provides Improvement in sensitivity and selectivity Reduced matrix effects ï‚¡ PDA and mass detection provide complementary information for peak assignment and structural confirmation of impurities]]>

Fast, selective, and sensitive methods can be developed for the analysis of impurities ï‚¡ Offering many business benefits using UPLC and UPC2 Increase in sample throughput Reduction in toxic solvent usage ï‚¡ Using mass spectral detection over UV detection provides Improvement in sensitivity and selectivity Reduced matrix effects ï‚¡ PDA and mass detection provide complementary information for peak assignment and structural confirmation of impurities]]>
Thu, 08 Jan 2015 05:49:20 GMT /slideshow/routine-impurity-analysis-with-uplcms-and-upc2ms/43315081 WatersChemical@slideshare.net(WatersChemical) Routine impurity analysis with UPLC/MS and UPC2/MS WatersChemical Fast, selective, and sensitive methods can be developed for the analysis of impurities ï‚¡ Offering many business benefits using UPLC and UPC2 Increase in sample throughput Reduction in toxic solvent usage ï‚¡ Using mass spectral detection over UV detection provides Improvement in sensitivity and selectivity Reduced matrix effects ï‚¡ PDA and mass detection provide complementary information for peak assignment and structural confirmation of impurities <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/anon-routineimpurityanalysiswithuplcmsandupc2msjanecooper-150108054920-conversion-gate01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Fast, selective, and sensitive methods can be developed for the analysis of impurities ï‚¡ Offering many business benefits using UPLC and UPC2 Increase in sample throughput Reduction in toxic solvent usage ï‚¡ Using mass spectral detection over UV detection provides Improvement in sensitivity and selectivity Reduced matrix effects ï‚¡ PDA and mass detection provide complementary information for peak assignment and structural confirmation of impurities
Routine impurity analysis with UPLC/MS and UPC2/MS from Waters Corporation - Chemical Materials
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Understanding complex materials using high definition mass spectrometry /slideshow/understanding-complex-materials-using-high-definition-mass-spectrometry/43314667 anon-understandingcomplexmaterialsusinghighdefinitionmassspectrometryeleanorriches-150108053423-conversion-gate01
Waters’ SYNAPT G2-Si HDMS instrument, with its quadrupole – ion mobility-ToF geometry, is an unrivalled tool for the characterisation of complex materials The orthogonal separation offered by ion mobility enables powerful structural elucidation workflows Collisional Cross Section (CCS) measurements provide valuable confirmatory data points Ion mobility-specific software allows interactive data evaluation and processing Partnering and collaborating with key thought leaders has resulted in the development of unique petroleum industry-specific data processing software]]>

Waters’ SYNAPT G2-Si HDMS instrument, with its quadrupole – ion mobility-ToF geometry, is an unrivalled tool for the characterisation of complex materials The orthogonal separation offered by ion mobility enables powerful structural elucidation workflows Collisional Cross Section (CCS) measurements provide valuable confirmatory data points Ion mobility-specific software allows interactive data evaluation and processing Partnering and collaborating with key thought leaders has resulted in the development of unique petroleum industry-specific data processing software]]>
Thu, 08 Jan 2015 05:34:23 GMT /slideshow/understanding-complex-materials-using-high-definition-mass-spectrometry/43314667 WatersChemical@slideshare.net(WatersChemical) Understanding complex materials using high definition mass spectrometry WatersChemical Waters’ SYNAPT G2-Si HDMS instrument, with its quadrupole – ion mobility-ToF geometry, is an unrivalled tool for the characterisation of complex materials The orthogonal separation offered by ion mobility enables powerful structural elucidation workflows Collisional Cross Section (CCS) measurements provide valuable confirmatory data points Ion mobility-specific software allows interactive data evaluation and processing Partnering and collaborating with key thought leaders has resulted in the development of unique petroleum industry-specific data processing software <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/anon-understandingcomplexmaterialsusinghighdefinitionmassspectrometryeleanorriches-150108053423-conversion-gate01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Waters’ SYNAPT G2-Si HDMS instrument, with its quadrupole – ion mobility-ToF geometry, is an unrivalled tool for the characterisation of complex materials The orthogonal separation offered by ion mobility enables powerful structural elucidation workflows Collisional Cross Section (CCS) measurements provide valuable confirmatory data points Ion mobility-specific software allows interactive data evaluation and processing Partnering and collaborating with key thought leaders has resulted in the development of unique petroleum industry-specific data processing software
Understanding complex materials using high definition mass spectrometry from Waters Corporation - Chemical Materials
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Innovation in size based polymer separations /slideshow/innovation-in-size-based-polymer-separations/43314172 innovationinsizebasedpolymerseparations-150108051818-conversion-gate01
The ACQUITY Advanced Polymer Chromatography (APCâ„¢) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more information about your polymers faster than ever before. This means better characterization, improved asset utilization and a superior solution for achieving corporate innovation and sustainability goals.]]>

The ACQUITY Advanced Polymer Chromatography (APCâ„¢) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more information about your polymers faster than ever before. This means better characterization, improved asset utilization and a superior solution for achieving corporate innovation and sustainability goals.]]>
Thu, 08 Jan 2015 05:18:17 GMT /slideshow/innovation-in-size-based-polymer-separations/43314172 WatersChemical@slideshare.net(WatersChemical) Innovation in size based polymer separations WatersChemical The ACQUITY Advanced Polymer Chromatography (APCâ„¢) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more information about your polymers faster than ever before. This means better characterization, improved asset utilization and a superior solution for achieving corporate innovation and sustainability goals. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/innovationinsizebasedpolymerseparations-150108051818-conversion-gate01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> The ACQUITY Advanced Polymer Chromatography (APCâ„¢) System is a breakthrough technology that defines the ultimate in size-based chromatographic separations, delivering more information about your polymers faster than ever before. This means better characterization, improved asset utilization and a superior solution for achieving corporate innovation and sustainability goals.
Innovation in size based polymer separations from Waters Corporation - Chemical Materials
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https://cdn.slidesharecdn.com/profile-photo-WatersChemical-48x48.jpg?cb=1559149318 Waters comprehensive solutions for the characterization of chemical materials help manufacturers cost-effectively accelerate the development of new products, improve the efficiency of manufacturing processes, and ensure final product quality. Solutions include sample preparation, LC columns, Advanced Polymer Chromatography (APC), liquid chromatography, mass spectrometry, and data analysis software. www.waters.com/waters/en_GB/Chemical/nav.htm?cid=134528338 https://cdn.slidesharecdn.com/ss_thumbnails/cosmeticallergensupdatefeb2016janecooperv2-160309161856-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/analysis-of-allergens-in-perfumes-cosmetics-and-personal-care-products/59324165 Analysis of Allergens ... https://cdn.slidesharecdn.com/ss_thumbnails/massdetectionforthecosmeticsindustryjanecooper-160309161209-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/mass-detection-for-the-cosmetics-industry/59323830 Mass Detection for the... https://cdn.slidesharecdn.com/ss_thumbnails/agrochemslidesharev3-160219203728-thumbnail.jpg?width=320&height=320&fit=bounds slideshow/latest-advancements-for-developing-next-generation-agrochemicals/58480535 Latest Advancements fo...