This document lists the 10 most dangerous drugs based on the percentage of serious reactions reported and the total number of serious reactions. The drugs range from cardiovascular and immunological agents to endocrine and antipsychotic drugs. The top most dangerous drug is cyclophosphamide, which had a 97% serious reaction rate and over 33,000 serious reactions reported. The document encourages subscribing to their YouTube channel for more information on dangerous drugs.
8. #10. Losartan
Percent of Reactions That Were Serious: 70%Number of Serious Reactions: 24,242Brand Names: CozaarTotal Number of Reported Reactions: 34,571Therapeutic Class: Cardiovascular Agent
9. #09. Infliximab
Percent of Reactions That Were Serious: 91%Number of Serious Reactions: 68,167Brand Names: RemicadeTotal Number of Reported Reactions: 74,738Therapeutic Class: Immunological Agent
10. #08. Tacrolimus
Percent of Reactions That Were Serious: 91%Number of Serious Reactions: 27,964Brand Names: ProtopicTotal Number of Reported Reactions: 30,262Therapeutic Class: Antipsoriatic
11. #07. Zoledronic Acid
Percent of Reactions That Were Serious: 93%Number of Serious Reactions: 35,581Brand Names: Reclast, ZometaTotal Number of Reported Reactions: 38,016Therapeutic Class: Calcium Regulator
12. #6. Dexamethasone
Percent of Reactions That Were Serious: 93%Number of Serious Reactions: 38,966Brand Names: Baycadron Elixer, Decadron, Dekpak 13 Day Taperpak,
Dexamethasone Intensol, Dexpak, Dexpak 10 Day Taperpak, Dexpak Jr, Zema-Pak
Total Number of Reported Reactions: 41,636Therapeutic Class: Endocrine-Metabolic
Agent
13. #5. Clozapine
Percent of Reactions That Were Serious: 95%Number of Serious Reactions: 29,470Brand Names: Clozaril, Fazaclo, VersaclozTotal Number of Reported Reactions: 30,914Therapeutic Class: Antipsychotic
14. #4. Rituximab
Percent of Reactions That Were Serious: 96%Number of Serious Reactions: 30,014Brand Names: RituxanTotal Number of Reported Reactions: 31,157Therapeutic Class: Antineoplastic Agent
15. #3. Bevacizumab
Percent of Reactions That Were Serious: 96%Number of Serious Reactions: 39,957Brand Names: AvastinTotal Number of Reported Reactions: 41,281Therapeutic Class: Immunological Agent
16. #2. Prednisolone
Percent of Reactions That Were Serious: 96%Number of Serious Reactions: 42,323Brand Names: Bubbli-Pred, Cotolone, Flo-Pred, Millipred, Millipred Dp,
Orapred, Orapred Odt, Pediapred, Prelone, Veripred 20, Pms-Prednisolone
Total Number of Reported Reactions: 43,817Therapeutic Class: Endocrine-Metabolic
Agent
17. #1. Cyclophosphamide
Percent of Reactions That Were Serious: 97%Number of Serious Reactions: 33,128Brand Names: Cytoxan, Cytoxan LyophilizedTotal Number of Reported Reactions: 34,076Therapeutic Class: Antineoplastic Agent