1. Natural history and prognostic indicators of survival in cirrhosis: A systematic review of
118 studies
Gennaro D'Amico, Guadalupe Garcia-Tsao, Luigi Pagliaro
Journal of Hepatology
Volume 44 Issue 1 Pages 217-231 (January 2006)
DOI: 10.1016/j.jhep.2005.10.013
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
2. Fig. 1
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
3. Fig. 2
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
4. Fig. 3
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
5. Fig. 4
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
6. Fig. 5
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
7. Fig. 6
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
8. Fig. 7
Journal of Hepatology 2006 44217-231DOI: (10.1016/j.jhep.2005.10.013)
Copyright 息 2005 European Association for the Study of the Liver Terms and Conditions
Editor's Notes
#3: The natural history of cirrhosis and components of prognosis. A simplified view.
#4: Cumulative proportion of patients transitioning from a compensated to a decompensated stage. Individual patient data from two prospective studies of the natural history of cirrhosis [8,10].
#5: Survival according to decompensation at diagnosis (A) and while remaining in the compensated or decompensated stages (B). Individual patient data from two prospective studies of the natural history of cirrhosis [8,10]. [This figure appears in colour on the web.]
#6: Clinical course of cirrhosis: 1-year outcome probabilities according to clinical stages.
#7: Number of variables included in the multivariable analysis as related to the number of observed deaths in 114 studies reporting this information. Each study is represented by a dot. The diagonal line represents the points where the ratio of deaths:variables is equal to 10. In the studies above the diagonal line, the ratio is <10 and there is a considerable risk of overfitting the data, and therefore of false-positive results. In studies below the diagonal line, the risk of overfitting is acceptably low.
#8: Box plots of one and two-year survival rates in ChildPugh (or variants) class A, B and C in the studies reporting this information. The number of studies providing the relevant information is reported in Table 2.
#9: Box plots of one and two-year survival rate in studies including only compensated (n=18 studies) or decompensated (n=23 studies) patients.