This study examines the moderating role of regulatory leisure coping styles on the relationship between job stress and well-being in female hospitality employees. The study found that (1) job stress has a negative impact on well-being, (2) planned-breather leisure coping style has a positive effect on well-being, and (3) avoidant leisure coping style has a negative effect on well-being. Additionally, planned-breather leisure coping style buffers the negative impact of job stress, while avoidant leisure coping style amplifies the negative impact of job stress on well-being. The results support the hypotheses proposed.