1. Acute appendicitis is caused by obstruction of the appendix lumen leading to infection. Common causes of obstruction include lymphoid hyperplasia, fecaliths, and tumors.
2. Appendicitis progresses from mucosal ischemia to inflammation, edema, and potential perforation within 48 hours if not treated. Perforation can lead to appendiceal mass or diffuse peritonitis.
3. Diagnosis is based on symptoms of migrating abdominal pain, laboratory tests showing elevated white blood cells, and physical exam maneuvers identifying tenderness. Imaging studies like ultrasound or CT scan may help if diagnosis is unclear.
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1. GIS-K-25
ACUTE APPENDICITIS
Appendiceal Mass / Abscess
Syahbuddin Harahap
Division of Digestive Surgery
Department of Surgery
Faculty of Medicine University of North Sumatera
Adam Malik Hospital
2. INTRODUCTION
The appendix is :
-Wormlike extension of the cecum (vermiform appendix).
-Length is 8-10 cm (ranging from 2-20 cm).
-Fifth month of gestation
-Several lymphoid follicles.
3. Etiology:
Obstruction of the lumen appendix followed by infection
Catarrhal appendicitis.
-lymphoid hyperplasia (60% children)
-Gastro enteritis
-Virus
-Acute respiratory infection
-Mononucleosis
Obstructive appendicitis
-fecalith 35% adults.
-foreign body / parasites (4%)
- tumors (1%)
4. Pathophysiology
Wangensteen proposed
1. Closed loop obstruction
2. Increase in luminal pressure.
3. Exceeds capillary pressure causes mucosal ischemia
4. Luminal bacterial overgrowth and translocation bacteria across the
appendiceal wall result :
-Inflammation
-Edema
-Necrosis perforation occur about 48 hours .
If the body successfully walls off the perforation Appendiceal Mass
If the perforation is not successfully walled off Diffuse peritonitis will
develop.
5. Problem:
Appendicitis can mimic several abdominal conditions.
Laboratory test
Imaging investigation
Statistics report
1 of 5 cases is misdiagnosed
Normal appendix is found in
15-40% Emergency appendectomy.(Negative Appendectomy)
8. Lab Studies:
Complete blood cell count
A mild elevation of WBCs (ie, >10,000/袖L)
Urinalysis
Mild pyuria relationship of the appendix with the right
ureter.
Severe pyuria in UTI.
For women of childbearing age,
Ectopic pregnancy test urin (beta-hCG)
9. On physical examination
Lying down
Flexing their hips
The most common symptom of appendicitis is :
- Acute abdominal pain.
- Epigastric or Periumbilical pain migrating to the
right lower quadrant (RLQ) of the abdomen.
- Vomiting, nausea, and anorexia
- Afebrile or has a low-grade fever , 38 尊 C
Higher fevers are associated with a perforated appendix
10. Special maneuvers
McBurney sign
McBurney's point
it is only the area
of greatest tenderness
Blumberg sign
Rovsings Sign
Dunphy sign Cough Test
Obturator sign
Psoas sign
Markle sign
12. INDICATIONS
Consider an appendectomy for patients with a
history of :
Persistent abdominal pain
Fever
Clinical signs of localized or diffuse peritonitis
Especially if leukocytosis is present.
14. MANTRELS SCORE
Characteristic Score
M = Migration of pain to the RLQ 1
A = Anorexia 1
N = Nausea and vomiting 1
T = Tenderness in RLQ 2
R = Rebound pain 1
E = Elevated temperature 1
L = Leukocytosis 2
S = Shift of WBC to the left 1
Total 10
A score of 7 or more is strongly predictive of acute appendicitis.
Alvarado score 1986
15. Sonography
Advantages of sonography
1. Noninvasiveness,
2. Short acquisition time
3. Lack of radiation exposure
4. Potential for diagnosis of
other causes of abdominal
pain
5. Pediatric patients
6. Women of childbearing age.
7. Pregnant women
normal less than 6 mm
16. CT scan
-Oral contrast medium
-Rectal Gastrografin enema
Reserved for patients
-Uncertain diagnosis
-Severe obesity.
more than 6 mm
17. If the clinical picture is unclear
Short period (4-6 h) of watchful waiting
USG / CT scan
-May improve diagnostic accuracy
Without a definite diagnosis
- return for continued or recurrent symptoms
- follow-up examination in 24 hours.
18. Complications
Perforation
General Secondary Peritonitis
Appendiceal Mass
Appendiceal Abscess
Pylephlebitis is suppurative thrombophlebitis of the
portal venous system
Hepatic absces
Chills
High fever
Jaundice
19. TREATMENT
Medical therapy
Resuscitated adequately with fluids .
Preoperative prophylactic antibiotics
-Acute Appendicitis single agent second-generation
cephalosporin.
-Perforated appendix triple antibiotic therapy
Ampicillin , gentamycin , metronidazol
Antibiotic prophylaxis should be administered before every
appendectomy.
Antibiotic treatment may be stopped.
-Becomes afebrile
-WBC count normalizes
20. Two approaches to appendectomy
1. Open Emergency Appendicectomy ( Appendectomy)
2. Laparoscopic appendectomy
If normal appendix removed need to look for:
- Meckel's diverticulum
- Acute salpingitis
- Crohn's disease
21. If the body successfully walls off the localized perforation
Appendiceal Mass
RLQ mass
The pain may actually improve.
Symptoms do not completely resolve.
Still have right lower quadrant pain
Decreased appetite
Change in bowel habits (eg, diarrhea, constipation)
Intermittent low-grade fever.
22. Treatment of
Appendiceal Mass
Nonoperative management
Becomes walled off by omentum and ajacent viscera.
Initially treated with intravenous broad-spectrum antibiotic
Appendiceal Abscess USG or CT scan
-Percutaneous aspiration
-Drain placement
Intravenous antibiotics are continued until the patient
- afebrile for 24 hours
- return of normal gastrointestinal function
- normal WBC count with a normal differential.
At this time, patients are switched to oral antibiotics for a total antibiotic
course of 10-14 days.
Traditionally, interval appendectomy is performed 6-8 weeks
later.