New Objective Inc. partners with various academic and corporate researchers to develop and improve ultra-high sensitivity LC-MS/MS technologies. Some of the key partnerships include developing the PicoChip nanospray source with several universities to provide easy-to-use yet high performance systems, and collaborating with a university to create a segmented flow nanospray system that can rapidly analyze multiple samples in an automated fashion. The overall goal of New Objective's partnerships is to advance mass spectrometry technologies through cooperation with customers.
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13 partnerships for ultra-high sensitivity lc-msms gary valaskovic - new objective
1. Partnerships for Ultra-high
Sensitivity LC-MS/MS
CPSA 2012 Vendor Session, Langhorne PA
Gary Valaskovic
New Objective Inc.
gary.valaskovic@newobjective.com
2. Skilled & Dedicated Staff in a
Responsive Environment
Customer & Technical Support
You!
Production Engineering
Partnership for Performance
3. Customer Partnerships with NOI
PicoChip Development
Nate Yates, University of Pittsburgh
Neil Kelleher, Northwestern Univesristy
John Yates, Scripps Research Institute
Steve Gygi, Harvard University
Workshops on Peptide Quantitation
Nalini Sadagopan, Agilent Technologies
Mike MacCoss, University of Washington
Microspray for Quantitation
Shane Needham, Alturas Analytics, Inc.
Brad Ackerman, Eli Lilly & Co.
Ultra-nano Separations for Biomarker Studies
Barry Karger, Northeastern University
Nanospray Source Development
Jarrod Marto, Dana Farber Cancer Institute
Susan Wientraub, UT Health Science
Heated Column Nanospray
Sue Abbatiello, Broad Institute
Ken Lewis, OpAns
Neil Kelleher, Northwestern University
Ultra-low Flow Pump
Jing-Tao Wu, Millenium Pharmaceuticals
Segmented Flow Nanospray
Bob Kennedy, University Michigan
Intact Protein Biomarkers
Ying Ge, University of Wisconsion
5. When Partnership becomes the future:
PicoChip system
We need this to be easy to use . . . .
. . . but we dont want to give up any
performance!
Nathan Yates
University of Pittsburgh
Partnership for Performance
6. PicoChip Easy to use, high
performance nanospray
Complex Simple
Specialized expertise Universal productivity
Mount source, connect Activate column Collect data
column to HPLC
Partnership for Performance
7. When Partnership becomes the future:
Chromatography is analog.
We need to digitize chromatography. . .
Mike S. Lee
(Circa 1998)
I have a dream To have a mass spec.
based plate reader
Jing-Tao Wu, Ph.D.
CPSA 2005 Closing Lecture, Princeton NJ
Partnership for Performance
8. When Partnership becomes the future:
Segmented Flow Electrospray
Bob Kennedy
University Michigan
Partnership for Performance
9. When Partnership becomes the future:
Segmented Flow Electrospray
Sample 4 Sample 1
Sample 5 Sample 2
Sample 6 Sample 3
ESI Mass
Nano Spray Spectrometer
Sample 1 Blanks Sample 4
Sample 2 Sample 5 Data
Pump Out
Sample 3 Sample 6
m/z m/z
10. When Partnership becomes the future:
Segmented Flow Electrospray
Sample 4 Sample 1
Sample 5 Sample 2
Sample 6 Sample 3
ESI Mass
Nano Spray Spectrometer
Sample 1 Blanks Sample 4
Sample 2 Sample 5 Data
Pump Out
Sample 3 Sample 6
m/z m/z
11. When Partnership becomes the future:
Segmented Flow Electrospray
Sample 4 Sample 1
Sample 5 Sample 2
Sample 6 Sample 3
ESI Mass
Nano Spray Spectrometer
Sample 1 Blanks Sample 4
Sample 2 Sample 5 Data
Pump Out
Sample 3 Sample 6
m/z m/z
12. When Partnership becomes the future:
Segmented Flow Electrospray
Sample 4 Sample 1
Sample 5 Sample 2
Sample 6 Sample 3
ESI Mass
Nano Spray Spectrometer
Sample 1 Blanks Sample 4
Sample 2 Sample 5 Data
Pump Out
Sample 3 Sample 6
m/z m/z