The document provides guidance on selecting, using, and caring for laboratory coats. It recommends wearing a lab coat when working with hazardous substances to provide skin and clothing protection from incidental contact and prevent contamination spread. Lab coats are not intended for major chemical handling or emergencies and offer limited chemical and flame resistance depending on material. The document reviews various lab coat materials and their properties, advising users to select coats based on the hazards in their lab. It also provides guidance on proper lab coat use, cleaning, and emergency procedures.