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2015 02-erbiumyag-lasers-effectively-refractory-melasma

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Roy Garcia

An Egyptian study examined the efficacy of erbium:YAG laser resurfacing in treating refractory melasma in 15 female patients. Histopathological and ultrastructural analysis before and after laser treatment found decreases in the number of melanocytes and concentration of melanin in melasma skin lesions post-surgery. Patients also experienced dramatic decreases in melasma area and severity. However, the laser treatment almost universally caused transient postinflammatory hyperpigmentation, requiring prompt intervention. The study concluded that erbium:YAG laser resurfacing can effectively improve refractory melasma.

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Erbium:YAG lasers effectively treat refractory melasma 6 February 2015 Erbium:YAG lasers can effectively treat refractory melasma, according to a study published in the February issue of the International Journal of Dermatology. (HealthDay)—Erbium:YAG lasers can effectively treat refractory melasma, according to a study published in the February issue of the International Journal of Dermatology. Enayat Attwa, M.D., from the Zagazig University in Egypt, and colleagues examined the efficacy of erbium:YAG lasers in the treatment of refractory melasma in a study involving 15 female patients. Participants underwent full-face skin resurfacing using an erbium:YAG laser. The authors examined histopathological and ultrastructural changes in melasma and control skin before and after surgery. The researchers found that, compared with normal skin, in melasma lesions there was an increase in the amount of melanin, staining intensity, and number of epidermal melanocytes. An increased number of mature melanosomes was seen in keratinocytes and melanocytes on electron microscopic analysis, with more marked cytoplasmic organelles in melasma skin than in biopsy specimens from normal skin. In melasma skin the number of melanocytes and concentration of melanin decreased after surgery, and there were dramatic decreases in the mean melasma area and severity index score. "Erbium:YAG laser resurfacing effectively improves melasma; however, the almost universal appearance of transient postinflammatory hyperpigmentation necessitates prompt and persistent intervention," the authors write. More information: Abstract Full Text (subscription or payment may be required) Copyright © 2015 HealthDay. All rights reserved. 1 / 2
APA citation: Erbium:YAG lasers effectively treat refractory melasma (2015, February 6) retrieved 15 March 2015 from http://medicalxpress.com/news/2015-02-erbiumyag-lasers-effectively-refractory-melasma.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Powered by TCPDF (www.tcpdf.org) 2 / 2

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2015 02-erbiumyag-lasers-effectively-refractory-melasma

  • 1. Erbium:YAG lasers effectively treat refractory melasma 6 February 2015 Erbium:YAG lasers can effectively treat refractory melasma, according to a study published in the February issue of the International Journal of Dermatology. (HealthDay)—Erbium:YAG lasers can effectively treat refractory melasma, according to a study published in the February issue of the International Journal of Dermatology. Enayat Attwa, M.D., from the Zagazig University in Egypt, and colleagues examined the efficacy of erbium:YAG lasers in the treatment of refractory melasma in a study involving 15 female patients. Participants underwent full-face skin resurfacing using an erbium:YAG laser. The authors examined histopathological and ultrastructural changes in melasma and control skin before and after surgery. The researchers found that, compared with normal skin, in melasma lesions there was an increase in the amount of melanin, staining intensity, and number of epidermal melanocytes. An increased number of mature melanosomes was seen in keratinocytes and melanocytes on electron microscopic analysis, with more marked cytoplasmic organelles in melasma skin than in biopsy specimens from normal skin. In melasma skin the number of melanocytes and concentration of melanin decreased after surgery, and there were dramatic decreases in the mean melasma area and severity index score. "Erbium:YAG laser resurfacing effectively improves melasma; however, the almost universal appearance of transient postinflammatory hyperpigmentation necessitates prompt and persistent intervention," the authors write. More information: Abstract Full Text (subscription or payment may be required) Copyright © 2015 HealthDay. All rights reserved. 1 / 2
  • 2. APA citation: Erbium:YAG lasers effectively treat refractory melasma (2015, February 6) retrieved 15 March 2015 from http://medicalxpress.com/news/2015-02-erbiumyag-lasers-effectively-refractory-melasma.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Powered by TCPDF (www.tcpdf.org) 2 / 2