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2018-05-13 CTCPure - pitchdeck

T
Thomas Burgers

The challenge: Cancer sucks. Many people suffer from cancer worldwide, but still a large part of the cancer treatments fail. This costs cancer patients lives and brings a large monetary cost to society as well. The challenge is that the effectiveness of cancer therapies can only be seen after weeks. Differences between people give rise to different reactions to therapies. Currently, a mix of drugs is given without knowing if they will work. To examine the effectiveness of drugs on individuals, we present the CTCPure. The solution: The CTCPure isolates and then characterizes circulating tumour cells from the human blood stream. By doing this characterization, a better prognosis and associated treatment can be done for each patient. Instead of determining treatments based on chance of success, treatment will be tailor made to each patient using the CTCPure. By doing this all on one chip, the process is cheap and fool-proof.

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2018-05-13 CTCPure - pitchdeck
2 Our Mission: Improve the prognosis and quality of life of cancer patients by offering a tool to measure treatment success Before administering the drug to the patient Our Vision: Personalized medicine is the future of medicine and the number of cancer patients is a growing
Im tired and I got an awful cough and sometimes I got chest pains Lets prescribe you some antibiotics 3 Week 1 Jack Jack Nothing has changed and my wife says I lost much weight I will refer you to the hospital for further investigation Week 2 Jack Im here for an MRI and a CT scan I see a suspicious area. I will refer you for a biopsy, you can stop by tomorrow MRI / CT scan Week 3 Jack Im here for a biopsy I will take a biopsy and it will be analyzed further under the microscope
4 Multidisciplinary meeting The MRI and CT scans revealed suspicious areas I analyzed the biopsy, there is some concern. I detected a certain type of lung cancer I think we should proceed with a treatment that has proven to be successful for about 70% of the patients Week 4 Jack Based on the results we would like to invite you for a conversation in the hospital Ill go there right now Weve got some bad news, you have lung cancer. I will explain the procedure you can expect Week 5
Treatment selected Treatment given to patient Cancer has grown / remained similar At least two weeks recovery before new treatment Cancer is reducedCancer not detectable Cancer diagnosed Check ups: 3 months, 6 months, each year New treatment selection At least two weeks recovery before new treatment 5
Effectiveness of chemotherapies only shown after weeks - Many possible chemotherapies High costs for cancer treatment - in 2015 worldwide $2 trillion (US dollars) Low concentration CTCs in blood and many contaminants - Personalized medicine: 1000 cells/mL for 1 gram of tumor Differences between people give different reactions to medication - Ethnicity, age, sex, genome, type of cancer 6
4. Advantages + 5. Solutions 7 Innovative microfluidic solution Combining multiple and most recent insights for filtration Not wasting money and time on ineffective treatments
8 Treatment selected Treatment given to patient Cancer has grown / remained similar At least two weeks recovery before new treatment Cancer is reducedCancer not detectable Cancer diagnosed Check ups: 3 months, 6 months, each year New treatment selection At least two weeks recovery before new treatment 6. Product
Financial benefits - $2.3 billion can be saved for treatment of all lung cancer patients worldwide each year - 350.000 patients dont get wrong treatment 9 7. Traction
8. Market 10 Know or at least attempt to estimate the size
9. Competition 11 What are the alternative solutions to the problem you are trying to solve
10. Business model 12 How are you planning to make money? Show a schedule when you expect revenues to pour in
11. Investing 13 What is your planned budget? What kind of budget are you looking for? We are looking at investment in information and funding for realisation of the products
12. Contact 14 Leave your contact details and let people know how to reach you quickly

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2018-05-13 CTCPure - pitchdeck

  • 2. 2 Our Mission: Improve the prognosis and quality of life of cancer patients by offering a tool to measure treatment success Before administering the drug to the patient Our Vision: Personalized medicine is the future of medicine and the number of cancer patients is a growing
  • 3. Im tired and I got an awful cough and sometimes I got chest pains Lets prescribe you some antibiotics 3 Week 1 Jack Jack Nothing has changed and my wife says I lost much weight I will refer you to the hospital for further investigation Week 2 Jack Im here for an MRI and a CT scan I see a suspicious area. I will refer you for a biopsy, you can stop by tomorrow MRI / CT scan Week 3 Jack Im here for a biopsy I will take a biopsy and it will be analyzed further under the microscope
  • 4. 4 Multidisciplinary meeting The MRI and CT scans revealed suspicious areas I analyzed the biopsy, there is some concern. I detected a certain type of lung cancer I think we should proceed with a treatment that has proven to be successful for about 70% of the patients Week 4 Jack Based on the results we would like to invite you for a conversation in the hospital Ill go there right now Weve got some bad news, you have lung cancer. I will explain the procedure you can expect Week 5
  • 5. Treatment selected Treatment given to patient Cancer has grown / remained similar At least two weeks recovery before new treatment Cancer is reducedCancer not detectable Cancer diagnosed Check ups: 3 months, 6 months, each year New treatment selection At least two weeks recovery before new treatment 5
  • 6. Effectiveness of chemotherapies only shown after weeks - Many possible chemotherapies High costs for cancer treatment - in 2015 worldwide $2 trillion (US dollars) Low concentration CTCs in blood and many contaminants - Personalized medicine: 1000 cells/mL for 1 gram of tumor Differences between people give different reactions to medication - Ethnicity, age, sex, genome, type of cancer 6
  • 7. 4. Advantages + 5. Solutions 7 Innovative microfluidic solution Combining multiple and most recent insights for filtration Not wasting money and time on ineffective treatments
  • 8. 8 Treatment selected Treatment given to patient Cancer has grown / remained similar At least two weeks recovery before new treatment Cancer is reducedCancer not detectable Cancer diagnosed Check ups: 3 months, 6 months, each year New treatment selection At least two weeks recovery before new treatment 6. Product
  • 9. Financial benefits - $2.3 billion can be saved for treatment of all lung cancer patients worldwide each year - 350.000 patients dont get wrong treatment 9 7. Traction
  • 10. 8. Market 10 Know or at least attempt to estimate the size
  • 11. 9. Competition 11 What are the alternative solutions to the problem you are trying to solve
  • 12. 10. Business model 12 How are you planning to make money? Show a schedule when you expect revenues to pour in
  • 13. 11. Investing 13 What is your planned budget? What kind of budget are you looking for? We are looking at investment in information and funding for realisation of the products
  • 14. 12. Contact 14 Leave your contact details and let people know how to reach you quickly

Editor's Notes

  • #7: Vertel wat CTCs zijn: Circulating tumour cells