This document provides guidance on conducting literature reviews. It discusses what a literature review is, including that it synthesizes existing published work on a topic into a summary. Literature reviews must be organized around a research question and identify gaps. The document also reviews how to systematically search literature databases like PubMed. It emphasizes using a structured search strategy based on population, determinant, and outcome terms along with Boolean operators. Key search tips include using Medical Subject Headings to enhance searches and saving strategies for future use.
3. Literature review
What it is
Scientific account of what has
already been published on a specific
topic
What it is not
Description or summary of all
published information
4. Literature reviews must.
1. Be organised around a specific
research question/ topic
2. Synthesize information into a
summary of what is and is not known
3. Identify areas of uncertainty/
controversy
4. Create questions that need further
research
5. Literature review
Involves two processes
1. Searching for information
2. Critically appraising the literature
8. Aim
Time saving
Restrict absolute number titles
Increase number relevant titles
Reduce Numbers Needed to Read
9. PubMed: What is it?
PubMed is a free database accessing
the MEDLINE database of citations,
abstracts and some full text articles on
life sciences and biomedical topics.
http://www.nlm.nih.gov/services/pubm
ed.html
10. PubMed: What is in it?
As of 8 March 2012 ~ over 21 million
citations for biomedical literature
from MEDLINE, life science journals,
and online books.
As of November 2011, 5,582 in
Medline
Different languages []
12. Search strategy in PubMed
Use knowledge, logic and creativity
Start with good Research Question
Population
Determinant/ Exposure
Outcome
Have several terms & synonyms for all
Be aware: UK / US spelling
13. Search strategy
Search #1: Population OR synonyms
Search #2: Determinant OR synonyms
Search #3: Outcome OR synonyms
Search #4: Combine #1, #2 and #3
Population (#1) AND Determinant (#2)
AND Outcome (#3)
14. Basic Search Scheme
Population Determinant/
Exposure
Outcome
term term term
Synonym 1 Synonym 1 Synonym 1
Synonym 2 Synonym 2 Synonym 2
Synonym 3 Synonym 3
OR OR OR
AND AND
16. How to search in PubMed?
Use Title/ Abstract in search builder,
under Advanced Search tab in
Pubmed
http://www.ncbi.nlm.nih.gov/pubmed
19. Research Question
Does renal impairment increase
mortality risk in Type 2 Diabetes
Mellitus?
Population: Type 2 DM
Determinant: Renal impairment
Outcome: Mortality
33. MeSH database
Medical Subject Headings (MeSH)
Systematic keyword catalogue
Related to content
5 MeSH terms per record
Based on title and abstract words
Partially manual process
Misclassification possible
MeSH = US spelling
34. MeSH database
Author keywords: NOT used
Only available 3 6 months after
publication
Adjustment to terms regular
Eg. 2007
22 terms removed
494 terms added
99 terms replaced
36. What else not to do
Use sparingly wildcard/ truncation *
Eg. Random*
Look at search details
Try NOT to use Boolean term NOT
38. Additional tips
Save search strategy under My NCBI
Save/ Email collection on articles
41. Nurses and other allied
health researchers
RQ: What is the level of knowledge and
attitudes of nursing students toward
tuberculosis?
Reason: To understand and determine
whether there is a need for improvement in
nursing education regarding tuberculosis.
42. Research Question
What is the level of knowledge and
attitudes of nursing students toward
tuberculosis?
Population: Nursing students
Determinant: Level of knowledge and
attitudes towards TB
Outcome: None
48. Practical session
Think of a research question and
prepare search terms
5 minutes
Go through PubMed search together
49. Literature search for
Qualitative Studies
Challenges of search in database:
Titles are descriptive c.f. RCT which usually has
clear description of population, determinants,
outcome and/or research method
Eg: Unbearable incidents: Failure to endure the
experience of Illness
Specific key terms difficult
Limited standardisation in presentation of abstract
c.f RCT : poor description of study method
Poor indexing: inconsistent indexing in Pubmed
Complex and difficult!
50. Literature search for
Qualitative Studies
Currently, no establish search strategy for
qualitative study
Potentially useful method:
Use appropriate MeSH terms in search:
eg: qualitative research, focus groups, narration,
anecdotes, grounded theory, attitude, knowledge,
practice
Limit search to publication types
Use a Quality research filter
Pubmed Health services research queries
http://www.nlm.nih.gov/nichsr/hedges/search.html
Finding Qualitative Research Articles: Pubmed . http://libguides.hsl.washington.edu/c.php?g=99112&p=642322