5-EAPB is an Entactogenic Amphetamine
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5-EAPB (1-(benzofuran-5-yl)-N-ethylpropan-2-amine) is an entactogenic amphetamine which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2013. https://brcshops.com/product/5-eapb/
![5-EAPB
The Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 4/4/2016 Page 3 of 5SWGDRUG.org/monographs.htm
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~5 mg/mL in CHCl3 (1M NaOH extraction)
Instrument: Agilent gas chromatograph operated in split mode with MS detector
Column: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25袖m
Carrier Gas: Helium at 1.0 mL/min
Temperatures: Injector: 280o
C MSD transfer line: 280o
C
MS Source: 230o
C MS Quad: 150o
C
Oven program:
1) 100o
C initial temperature for 1.0 min
2) Ramp to 300o
C at 12 o
C/min
3) Hold final temperature for 9.0 min
Injection Parameters: Split Ratio = 20:1, 1 袖L injected
MS Parameters: Mass scan range: 30-550 amu Threshold: 100
Tune file: stune.u Acquisition mode: scan
Retention Time: 7.300 min
EI Mass Spectrum: 5-EAPB HCl; Lot# 0455564-11
m/z200180160140120100806040
[x10
5
]Intensity
2
4
30303030303030303030303030303030303030303030
44444444444444444444444444444444444444444444 44444444444444444444444444444444444444444444
51515151515151515151515151515151515151515151
56565656565656565656565656565656565656565656
62626262626262626262626262626262626262626262
63636363636363636363636363636363636363636363
72727272727272727272727272727272727272727272
77777777777777777777777777777777777777777777
89898989898989898989898989898989898989898989
91919191919191919191919191919191919191919191
102102102102102102102102102102102102102102102102102102102102102102
102102102102102102102102102102102102102102102102102102102102102102
115115115115115115115115115115115115115115115115115115115115115115
115115115115115115115115115115115115115115115115115115115115115115
131131131131131131131131131131131131131131131131131131131131131131
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144144144144144144144144144144144144144144144144144144144144144144
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158158158158158158158158158158158158158158158158158158158158158158
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186186186186186186186186186186186186186186186186186186186186186186
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202202202202202202202202202202202202202202202202202202202202202202
m/z200180160140120100806040
[x10
4
]Intensity
2
4
30303030303030303030303030303030303030303030
42424242424242424242424242424242424242424242
44444444444444444444444444444444444444444444
44444444444444444444444444444444444444444444
50505050505050505050505050505050505050505050
51515151515151515151515151515151515151515151
56565656565656565656565656565656565656565656
62626262626262626262626262626262626262626262
63636363636363636363636363636363636363636363
64646464646464646464646464646464646464646464
72727272727272727272727272727272727272727272
73737373737373737373737373737373737373737373
77777777777777777777777777777777777777777777
89898989898989898989898989898989898989898989
91919191919191919191919191919191919191919191
91919191919191919191919191919191919191919191
102102102102102102102102102102102102102102102102102102102102102102
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103103103103103103103103103103103103103103103103103103103103103103
115115115115115115115115115115115115115115115115115115115115115115
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128128128128128128128128128128128128128128128128128128128128128128
131131131131131131131131131131131131131131131131131131131131131131
131131131131131131131131131131131131131131131131131131131131131131
143143143143143143143143143143143143143143143143143143143143143143
144144144144144144144144144144144144144144144144144144144144144144 145145145145145145145145145145145145145145145145145145145145145145
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5-EAPB is an Entactogenic Amphetamine
- 1. 5-EAPB The Drug Enforcement Administration's Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. Latest Revision: 4/4/2016 Page 1 of 5SWGDRUG.org/monographs.htm 1. GENERAL INFORMATION IUPAC Name: 1-(1-benzofuran-5-yl)-N-ethylpropan-2-amine CAS#: 1823776-22-2 (HCl) Synonyms: 5-(2-ethylaminopropyl)benzofuran Source: DEA Reference Material Collection Appearance: White powder (Hydrochloride) UVmax(nm): Not determined 2. CHEMICAL AND PHYSICAL DATA 2.1 CHEMICAL DATA Form Chemical Formula Molecular Weight Melting Point (o C) Base C13H17NO 203 Not Determined HCl C13H17NO HCl 239 154.7 O CH3 NH CH3
- 2. 5-EAPB The Drug Enforcement Administration's Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. Latest Revision: 4/4/2016 Page 2 of 5SWGDRUG.org/monographs.htm 3. QUALITATIVE DATA 3.1 NUCLEAR MAGNETIC RESONANCE Sample Preparation: Dilute analyte to ~6 mg/mL in D2O co ntaining TSP for 0 ppm reference and maleic acid as quantitative internal standard. Instrument: 400 MHz NMR spectrometer Parameters: Spectral width: at least containing -3 ppm through 13 ppm Pulse angle: 90o Delay between pulses: 45 seconds 1 HNMR: 5-EAPB HCl; Lot# 0455564-11; D2O; 400MHz 7.5 7.0 6.5 6.0 5.5 5.0 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5 0 61311121 7.775 1 7.5757.550 2 7.26 7.24 1 6.895 6.885 1 3.65 3.60 1 3.20 3.15 3.10 3 2.950 1 1.275 6 maleic acid HDO TSP
- 3. 5-EAPB The Drug Enforcement Administration's Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. Latest Revision: 4/4/2016 Page 3 of 5SWGDRUG.org/monographs.htm 3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY Sample Preparation: Dilute analyte ~5 mg/mL in CHCl3 (1M NaOH extraction) Instrument: Agilent gas chromatograph operated in split mode with MS detector Column: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25袖m Carrier Gas: Helium at 1.0 mL/min Temperatures: Injector: 280o C MSD transfer line: 280o C MS Source: 230o C MS Quad: 150o C Oven program: 1) 100o C initial temperature for 1.0 min 2) Ramp to 300o C at 12 o C/min 3) Hold final temperature for 9.0 min Injection Parameters: Split Ratio = 20:1, 1 袖L injected MS Parameters: Mass scan range: 30-550 amu Threshold: 100 Tune file: stune.u Acquisition mode: scan Retention Time: 7.300 min EI Mass Spectrum: 5-EAPB HCl; Lot# 0455564-11 m/z200180160140120100806040 [x10 5 ]Intensity 2 4 30303030303030303030303030303030303030303030 44444444444444444444444444444444444444444444 44444444444444444444444444444444444444444444 51515151515151515151515151515151515151515151 56565656565656565656565656565656565656565656 62626262626262626262626262626262626262626262 63636363636363636363636363636363636363636363 72727272727272727272727272727272727272727272 77777777777777777777777777777777777777777777 89898989898989898989898989898989898989898989 91919191919191919191919191919191919191919191 102102102102102102102102102102102102102102102102102102102102102102 102102102102102102102102102102102102102102102102102102102102102102 115115115115115115115115115115115115115115115115115115115115115115 115115115115115115115115115115115115115115115115115115115115115115 131131131131131131131131131131131131131131131131131131131131131131 131131131131131131131131131131131131131131131131131131131131131131 144144144144144144144144144144144144144144144144144144144144144144 145145145145145145145145145145145145145145145145145145145145145145 158158158158158158158158158158158158158158158158158158158158158158 159159159159159159159159159159159159159159159159159159159159159159 186186186186186186186186186186186186186186186186186186186186186186 188188188188188188188188188188188188188188188188188188188188188188 202202202202202202202202202202202202202202202202202202202202202202 m/z200180160140120100806040 [x10 4 ]Intensity 2 4 30303030303030303030303030303030303030303030 42424242424242424242424242424242424242424242 44444444444444444444444444444444444444444444 44444444444444444444444444444444444444444444 50505050505050505050505050505050505050505050 51515151515151515151515151515151515151515151 56565656565656565656565656565656565656565656 62626262626262626262626262626262626262626262 63636363636363636363636363636363636363636363 64646464646464646464646464646464646464646464 72727272727272727272727272727272727272727272 73737373737373737373737373737373737373737373 77777777777777777777777777777777777777777777 89898989898989898989898989898989898989898989 91919191919191919191919191919191919191919191 91919191919191919191919191919191919191919191 102102102102102102102102102102102102102102102102102102102102102102 102102102102102102102102102102102102102102102102102102102102102102 103103103103103103103103103103103103103103103103103103103103103103 115115115115115115115115115115115115115115115115115115115115115115 115115115115115115115115115115115115115115115115115115115115115115 116116116116116116116116116116116116116116116116116116116116116116 128128128128128128128128128128128128128128128128128128128128128128 131131131131131131131131131131131131131131131131131131131131131131 131131131131131131131131131131131131131131131131131131131131131131 143143143143143143143143143143143143143143143143143143143143143143 144144144144144144144144144144144144144144144144144144144144144144 145145145145145145145145145145145145145145145145145145145145145145 157157157157157157157157157157157157157157157157157157157157157157 158158158158158158158158158158158158158158158158158158158158158158 159159159159159159159159159159159159159159159159159159159159159159 186186186186186186186186186186186186186186186186186186186186186186 188188188188188188188188188188188188188188188188188188188188188188 202202202202202202202202202202202202202202202202202202202202202202
- 4. 5-EAPB The Drug Enforcement Administration's Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. Latest Revision: 4/4/2016 Page 4 of 5SWGDRUG.org/monographs.htm 3.3 INFRARED SPECTROSCOPY (FTIR) Instrument: FTIR with diamond ATR attachment (1 bounce) Scan Parameters: Number of scans: 32 Number of background scans: 32 Resolution: 4 cm-1 Sample gain: 8 Aperture: 150 FTIR ATR (Diamond 1 Bounce): 5-EAPB HCl; Lot# 0455564-11 Wavenumber (cm-1)4000 3500 3000 2500 2000 1500 1000 %Transmittance 60 65 70 75 80 426426426426426426426426426426426426426426426426426426426426426426 455455455455455455455455455455455455455455455455455455455455455455 604604604604604604604604604604604604604604604604604604604604604604 646646646646646646646646646646646646646646646646646646646646646646 746746746746746746746746746746746746746746746746746746746746746746 760760760760760760760760760760760760760760760760760760760760760760 771771771771771771771771771771771771771771771771771771771771771771 785785785785785785785785785785785785785785785785785785785785785785 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- 5. 5-EAPB The Drug Enforcement Administration's Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. Latest Revision: 4/4/2016 Page 5 of 5SWGDRUG.org/monographs.htm https://en.wikipedia.org/wiki/5-EAPB http://forendex.southernforensic.org/index.php/detail/index/1303 4. ADDITIONAL RESOURCES Wikipedia Forendex