2. Case Background
A 7 year old healthy child went camping with
his scouting team at a lake, where he swam
for a long time. 7 days later, he developed a
severe headache, high fever, nausea,
vomiting, photophobia and meningismus.
3. What will be your next step?
A. Empiric broad spectrum antibiotics + Anti
epileptics
B. Acyclovir + Anti epileptics
C. Send for immediate Blood culture
D. Lumbar puncture
E. Wait and watch + Careful Mannitol Infusion
F. Order CT Scan
4. A.
No response after days 2 and 3, patient
becomes comatose, has seizures, needs
airway protection:
Continue Antibiotic therapy for days 4 and 5
Go back to do list and restart!
+ 5
5. B.
No Response after days 2 and 3, patient
becomes comatose, has seizures, needs
airway protection :
Continue Anti Virals for Days 4 and 5
Go back to first step and restart!
- 5
6. C.
Methicillin Resistant, Coagulase Negative
Staphylococcus cultured.
Start:
IV Cefepime
IV Quinupristine/Dalfopristine
IV Vancomycin
IV Linezolid
Resend blood for culture
- 5
8. IV Drugs.
No response after days 2 and 3:
Continue Antibiotic therapy for days 4 and 5
Go back to do list and restart!
- 5
9. D.
High intracranial
pressure observed
during LP
WBC = 15,000/microlit
Protein = (very high)
Glucose = (very low)
More 際際滷s
Provisional Diagnosis
Next step
+ 10
11. Next step
Start:
Amphotericin B
Fluconazole
Anti TB drugs
Albendazole + Ivermectin
Piperacillin/Tazobactam
Meropenem or Imipenem/Cilastatin
12. Amphotericin B.
CORRECT drug choice
Patient becomes comatose
Respiratory failure
Intubated and put on ventilator
No response to empirical
antibiotic/antiviral/antifungal therapy
Death on day 3!
Provisional diagnosis? + 10
13. Other Drugs.
INCORRECT drug choice
Patient becomes comatose
Respiratory failure
Intubated and put on ventilator
No response to empirical
antibiotic/antiviral/antifungal therapy
Death on day 3!
Provisional diagnosis? - 5
14. E.
Patient becomes comatose
Respiratory failure
Intubated and put on ventilator
No response to empirical
antibiotic/antiviral/antifungal therapy
Death on day 5!
Provisional diagnosis?
- 5