This study aimed to determine the frequency of antibiotic-resistant E. coli strains in people's digestive systems. Stool samples were collected from 100 randomly selected men and women aged 10-92 years old and tested for resistance to ampicillin and tetracycline. The results showed 30% of men and 24% of women had ampicillin-resistant E. coli, while 12% of both men and women had tetracycline-resistant strains. Resistance was slightly higher in people over age 50 who had longer lifetime exposure to the antibiotics. This suggests antibiotics should be carefully administered and monitored by healthcare professionals.
1 of 2
More Related Content
Abstract
1. Abstract
The Frequency of Antibiotic Resistant E. coli in
Alimentary Tracts
Objective: The objective is to determine if the average American has ampicillin- and
tetracycline-resistant strains of E. coli in their alimentary tract.
Materials and Methods: Informed consent was obtained from 100 randomly
selected people, 50 men and 50 women ranging in age from 10 to 92 years. An
isolate of E. coli was obtained from the stool of each subject and grown in the
presence of tetracycline and ampicillin. The area of inhibition was measured and
compared to that of a non-resistant strain of E. coli. The percentage of sensitive and
resistant organisms was determined by age and sex.
Results: Thirty percent of the men and 24% of the women were found to have
ampicillin-resistant E. coli. The majority of the sample population was found to be
under the age of 50. Slightly more people age 50 and over were found to be resistant
than those under 50. Only 12% of both men and women were found to have
tetracycline-resistant E. coli, with the older population again having a somewhat
higher incidence of resistance.
Discussion: Penicillin and its derivatives such as ampicillin, were the first
commercially available antibiotics. Tetracycline was introduced later. The length of
exposure to the antibiotics is reflected in the greater percentage of subjects with
ampicillin-resistant E. coli (24% to 30%), compared to those with tetracycline-
resistant organisms (12%). In addition, subjects age 50 and over who would have a
longer life-time exposure to both antibiotics were more likely to harbor antibiotic
resistant E. coli. These data suggest that antibiotics should be carefully dispensed
and monitored by health care professionals.
2. Abstract
The Effect of Surface Finish on Rocket Drag
Objective: My project was to determine if surface finish has an effect on the drag of a
model rocket. I believe that a model with a smooth surface will have lower drag and
will reach higher altitudes.
Materials and Methods: Five model rockets with identical size and shape, but
different surface preparations, were constructed. One rocket was left with an
unfinished surface, three had surfaces finished to various degrees of smoothness, and
the fifth rocket had its surface sealed, primed, sanded to 600 grit, painted, and covered
with clear gloss. The rockets were ballasted to weigh the same and flown 10 times
each with B5-4 motors.
Results: The rocket with the clear gloss finish consistently reached the highest
altitudes of all 5 rockets, while the unfinished rocket consistently reached the lowest
altitude.
Conclusions: My conclusion is that surface finish has an important role in model
rocket drag and rockets with carefully prepared surfaces will reach higher altitudes.