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Alzheimer's Disease
The Worst Plague of The 21st Century
What is Alzheimer's disease?
Alzheimer's disease is a neurological
disorder in which the death of brain
cells causes memory loss and cognitive
decline.
Dr. Alois Alzheimer
The first person to describe this disease
The first Alzheimer Patient in History
Auguste Deter
The Haunting case of Auguste D.
A 51 years old women, a patient who had
profound memory loss, unfounded suspicions
about her family, shrinkage in her brain and other
worsening psychological changes like, cognitive
and language deficits, auditory hallucinations,
delusions, paranoia and aggressive behaviour.
What causes Alzheimer's disease
Scientists dont yet fully understand what causes
Alzheimers disease, but it is clear that it develops because
of a complex series of events that take place in the brain
over a long period of time. It is likely that the causes
include genetic, environmental, and lifestyle factors.
Because people differ in their genetic make-up and lifestyle,
the importance of these factors for preventing or delaying
Alzheimers differs from person to person.
Signs and Symptoms
Very early sign and symptoms
Memory problems are typically one of the first
warning signs of cognitive loss, possibly due to the
development of Alzheimers disease. A decline in
other aspects of cognition, such as word-finding,
vision/spatial issues, and impaired reasoning or
judgment, may also signal the very early stages of
Alzheimers disease.
Mild Alzheimer's Disease

Alzheimers disease progresses,
memory loss worsens, and changes in
other cognitive abilities which are
evident.
Moderate Alzheimers disease

In this stage, damage occurs in areas of the
brain that control language, reasoning,
sensory processing, and conscious thought.
Memory loss and confusion grow worse,
and people begin to have problems
recognizing family and friends.
Severe Alzheimers disease
By the final stage, plaques and tangles have
spread throughout the brain, and brain tissue has
shrunk significantly. People with severe
Alzheimers cannot communicate and are
completely dependent on others for their care.
Near the end, the person may be in bed most or all
of the time as the body shuts down.
Healthy and Affected Neurons
Changes occurring in brain on every
stage of Alzheimers disease
Alzheimers
Genetics
Alzheimer's disease have a tendency to
pass from generation to generation. It is
a genetic disease which has maximum
chances of getting inherited from
parents.
Diagnosing Alzheimer's disease
To diagnose Alzheimers, doctors may:
 Ask questions about overall health, past medical
problems, ability to carry out daily activities, and
changes in behaviour and personality.
 Conduct tests of memory, problem solving, attention,
counting, and language.
 Carry out standard medical tests, such as blood and
urine tests, to identify other possible causes of the
problem.
 Perform brain scans, such as computed tomography
(CT) or magnetic resonance imaging (MRI), to
distinguish Alzheimers from other possible causes
for symptoms, like stroke or tumor.
Treatment
There is no specific treatment to cure Alzheimers
disease completely with the prescribed medicines
as it is most complex disease ever found in history.
There are some prescribed medicines by U.S. food
and drug administration to treat Alzheimers
disease but cant cure it completely, it can just
stabilize the memory and some brain function for
limited period of time.
References
http://www.medicalnewstodayhttp://www.medicinenet.com/dementia
_pictures_slideshow/article.htm
http://www.medicalnewstoday.com/articles/159442.php
http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp
http://www.alzheimers.org.uk/site/scripts/documents_info.php?docu
mentID=100
http://www.nytimes.com/health/guides/disease/alzheimersdisease/overview.html.com/articles/159442.php

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