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Vivite: The Advanced Glycolic Acid/Antioxidant Line

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The Naderi Center for Rhinoplasty & Cosmetic Surgery
The Naderi Center for Rhinoplasty & Cosmetic Surgery

VIVIT速 is an advanced skin care system developed with GLX TechnologyTM to help improve the appearance of mild to moderate photodamaged skin in as few as 3 weeks. The VIVIT速 line includes facial cleansers, serums, eye treatments, and moisturizers. Clinical trials showed VIVIT速 helped improve fine lines and wrinkles, smoothness, and moisture. VIVIT速 Vibrance is a natural hydroquinone-free agent that helped improve the appearance of fine lines, roughness, and hyperpigmentation after 8 weeks of treatment in a clinical trial.

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VIVIT速 The Advanced Glycolic Acid/Antioxidant Line
The Role of Physician-Dispensed Topical Aesthetics Topical aesthetics can be used to help improve the appearance of skins condition alone or in conjunction with other procedures Topical aesthetics can complement and help promote skin treatments eg, moisturizers can be beneficial with treatments that leave the skin dry Patients pleased with their results from facial injectables may wish to complement them through a physician-dispensed skin care regimen Aesthetic improvements may translate into greater interest in more advanced procedures ie, dermal fillers, facial injectables, and/or lasers and peels Behl P. Professional Skin Care 2006, Vol I: United States. Little Falls, NJ: Kline & Company, Inc.
VIVIT速 Skin Care Products Are Appropriate for All Patients VIVIT速 is an advanced glycolic and natural antioxidant system that helps improve the appearance of mild to moderate photodamaged skin in as few as 3 weeks1,2 Advanced skin care system designed with GLX Technology* Helps improve the appearance of mild to moderate photodamaged skin For all skin care patients For patients who are dissatisfied with their current skin care system Appropriate for all skin types (universal anti-aging system) *GLX Technology is owned by Pharma Cosmetix Research, LLC. 1. Data on file. Allergan, Inc.; 2. Downie JB. Cosmet Dermatol. 2008;21:168-175.
VIVIT速 Line of Skin Care Products VIVIT速 Core System VIVIT速 Exfoliating Facial Cleanser VIVIT速 Daily Antioxidant Facial Serum VIVIT速 Revitalizing Eye Treatment VIVIT速 Night Renewal Facial Cream VIVIT速 Daily Facial Cleanser VIVIT速 Daily Facial Moisturizer SPF 30 VIVIT速 Vibrance Therapy VIVIT速 Replenish Hydrating Cleanser VIVIT速 Replenish Hydrating Cream VIVIT速 GLX I Facial Peel Gel VIVIT速 Defining Lip Plumper VIVIT速 Daily Firming Lotion VIVIT速 Back Bar Products VIVIT速 Exfoliating Facial Cleanser VIVIT速 Replenish Hydrating Cream Data on file. Allergan, Inc.
VIVIT速 Skin Care Products Are Developed With Proprietary GLX Technology VIVIT速 Skin Care Products are developed with proprietary GLX Technology This formula matrix is designed to help act as a vehicle for the deep penetration of glycolic acid bound to natural antioxidants Helps enhance the skins natural production of hyaluronic acid and epidermal growth factor (EGF); stimulates collagen; and protects epidermal cells Helps allow high amounts of glycolic acid to be released over an extended period for maximum efficacy with minimum irritation Helps raise product pH closer to that of normal skin to reduce irritation Helps retain a reservoir of alpha hydroxy acid (AHA) for secondary exfoliation Contains botanicals and innovative ingredients: chamomile, aloe, wild mango butter, green tea, pomegranate, licorice root, caffeine, olive leaf extract, algae extract peptides, superoxide dismutase, exfoliating microbeads, and interference pearls *GLX Technology is owned by Pharma Cosmetix Research, LLC. Data on file. Allergan, Inc.
In a 3-Week Clinical Trial, VIVIT速 Core Systems Helped Improve Photodamaged Skin After 3 Weeks Use 100 90 N=24 80 70 65 From Baseline (%) 60 Improvement 54 50 40 36 30 22 20 10 0 Fine Lines and Moisture* Smoothness Dryness Wrinkles *Mean value of suborbital (38%) and cheek areas (34%). Downie JB. Cosmet Dermatol. 2008;21:168-175.
VIVIT速 Vibrance Is a Natural Hydroquinone-Free Agent for Skin Brightening A natural hydroquinone-free agent for skin brightening and even skin tone Anti-aging GLX Technology (glycolic acid, ammonium glycolate, and olive leaf extract) Skin brightening/antioxidant complex: Tyrosinase inhibition methyl dihydroxybenzoate Increase cellular activity retinol and glycolic Oxidative inhibition soy isoflavones, glycyrrhiza glabra (licorice) root extract, morus nigra (mulberry) fruit extract, grape (vitis vinifera) extract, feoniculum vulgare (fennel) seed extract, lycopene, olea europaea (olive) leaf extract, superoxide dismutase, tocopherol, and magnesium ascorbyl phosphate Skin redness reducing actives: allantoin glycyrrhetinic, acid bisabolol, and camellia oleifera (Japanese green tea) leaf extract Humectants: glycerin and butylene glycol Emollients: dimethicone and squalane *GLX Technology is owned by Pharma Cosmetix Research, LLC. Data on file. Allergan, Inc.
VIVIT速 Vibrance 8-Week Clinical Trial Design An 8-week, randomized, double-blind, split-face study of VIVIT速 Vibrance used on one side of the face (also randomized) and a 4% HQ bleaching gel used on the other side of the face Expert grader evaluations were made at baseline and at 4 and 8 weeks Twenty-one women aged 20 to 75 years with moderate pigmentation of the face participated in the trial; 18 (86%) completed the study No patients dropped out of the clinical trial due to irritation McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
VIVIT速 Vibrance Helped Improve the Appearance of Fine Lines/Wrinkles, Skin Roughness, and Hyperpigmentation After 8 Weeks of Treatment Expert Evaluator 100 90 N=21 Percent Improvement 80 70% 70 66% 63% 61% 60 50 40 30 27% 27% 20 10 0 Fine Lines/Wrinkles Roughness Hyperpigmentation Natural-based Bleaching Cream 4% HQ Gel McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
VIVIT速 Vibrance Helped Improve Hyperpigmentation After 8 Weeks of Treatment Processed UV RBX Brown (hyperpigmentation) Baseline Week 8 Baseline Week 8 Photos are completely untouched. Individual results may vary. McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
Summary Topical aesthetics can be used to help improve the appearance of skins condition alone or in conjunction with other procedures VIVIT速 is an advanced glycolic and natural antioxidant system that helps improve the appearance of mild to moderate photodamaged skin in as few as 3 weeks1,2 VIVIT速 Skin Care Products are developed with proprietary GLX Technology* which is designed to help act as a vehicle for the deep penetration of glycolic acid bound to natural antioxidants VIVIT速 Vibrance is a natural hydroquinone-free agent for skin brightening and even skin tone VIVIT速 Vibrance helped improve the appearance of fine lines and wrinkles, skin roughness, and hyperpigmentation after 8 weeks of treatment3 *GLX Technology is owned by Pharma Cosmetix Research, LLC. 1. Data on file. Allergan, Inc.; 2. Downie JB. Cosmet Dermatol. 2008;21:168-175; 3. McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
Allergan Supports the Pillars of Successful Practice Patient loyalty and practice growth Industry- Familiarity, Patient Practice leading trust, and satisfaction building products confidence APC72LJ10 息2010 Allergan, Inc. 速 and marks owned by Allergan, Inc.

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Vivite: The Advanced Glycolic Acid/Antioxidant Line

  • 1. VIVIT速 The Advanced Glycolic Acid/Antioxidant Line
  • 2. The Role of Physician-Dispensed Topical Aesthetics Topical aesthetics can be used to help improve the appearance of skins condition alone or in conjunction with other procedures Topical aesthetics can complement and help promote skin treatments eg, moisturizers can be beneficial with treatments that leave the skin dry Patients pleased with their results from facial injectables may wish to complement them through a physician-dispensed skin care regimen Aesthetic improvements may translate into greater interest in more advanced procedures ie, dermal fillers, facial injectables, and/or lasers and peels Behl P. Professional Skin Care 2006, Vol I: United States. Little Falls, NJ: Kline & Company, Inc.
  • 3. VIVIT速 Skin Care Products Are Appropriate for All Patients VIVIT速 is an advanced glycolic and natural antioxidant system that helps improve the appearance of mild to moderate photodamaged skin in as few as 3 weeks1,2 Advanced skin care system designed with GLX Technology* Helps improve the appearance of mild to moderate photodamaged skin For all skin care patients For patients who are dissatisfied with their current skin care system Appropriate for all skin types (universal anti-aging system) *GLX Technology is owned by Pharma Cosmetix Research, LLC. 1. Data on file. Allergan, Inc.; 2. Downie JB. Cosmet Dermatol. 2008;21:168-175.
  • 4. VIVIT速 Line of Skin Care Products VIVIT速 Core System VIVIT速 Exfoliating Facial Cleanser VIVIT速 Daily Antioxidant Facial Serum VIVIT速 Revitalizing Eye Treatment VIVIT速 Night Renewal Facial Cream VIVIT速 Daily Facial Cleanser VIVIT速 Daily Facial Moisturizer SPF 30 VIVIT速 Vibrance Therapy VIVIT速 Replenish Hydrating Cleanser VIVIT速 Replenish Hydrating Cream VIVIT速 GLX I Facial Peel Gel VIVIT速 Defining Lip Plumper VIVIT速 Daily Firming Lotion VIVIT速 Back Bar Products VIVIT速 Exfoliating Facial Cleanser VIVIT速 Replenish Hydrating Cream Data on file. Allergan, Inc.
  • 5. VIVIT速 Skin Care Products Are Developed With Proprietary GLX Technology VIVIT速 Skin Care Products are developed with proprietary GLX Technology This formula matrix is designed to help act as a vehicle for the deep penetration of glycolic acid bound to natural antioxidants Helps enhance the skins natural production of hyaluronic acid and epidermal growth factor (EGF); stimulates collagen; and protects epidermal cells Helps allow high amounts of glycolic acid to be released over an extended period for maximum efficacy with minimum irritation Helps raise product pH closer to that of normal skin to reduce irritation Helps retain a reservoir of alpha hydroxy acid (AHA) for secondary exfoliation Contains botanicals and innovative ingredients: chamomile, aloe, wild mango butter, green tea, pomegranate, licorice root, caffeine, olive leaf extract, algae extract peptides, superoxide dismutase, exfoliating microbeads, and interference pearls *GLX Technology is owned by Pharma Cosmetix Research, LLC. Data on file. Allergan, Inc.
  • 6. In a 3-Week Clinical Trial, VIVIT速 Core Systems Helped Improve Photodamaged Skin After 3 Weeks Use 100 90 N=24 80 70 65 From Baseline (%) 60 Improvement 54 50 40 36 30 22 20 10 0 Fine Lines and Moisture* Smoothness Dryness Wrinkles *Mean value of suborbital (38%) and cheek areas (34%). Downie JB. Cosmet Dermatol. 2008;21:168-175.
  • 7. VIVIT速 Vibrance Is a Natural Hydroquinone-Free Agent for Skin Brightening A natural hydroquinone-free agent for skin brightening and even skin tone Anti-aging GLX Technology (glycolic acid, ammonium glycolate, and olive leaf extract) Skin brightening/antioxidant complex: Tyrosinase inhibition methyl dihydroxybenzoate Increase cellular activity retinol and glycolic Oxidative inhibition soy isoflavones, glycyrrhiza glabra (licorice) root extract, morus nigra (mulberry) fruit extract, grape (vitis vinifera) extract, feoniculum vulgare (fennel) seed extract, lycopene, olea europaea (olive) leaf extract, superoxide dismutase, tocopherol, and magnesium ascorbyl phosphate Skin redness reducing actives: allantoin glycyrrhetinic, acid bisabolol, and camellia oleifera (Japanese green tea) leaf extract Humectants: glycerin and butylene glycol Emollients: dimethicone and squalane *GLX Technology is owned by Pharma Cosmetix Research, LLC. Data on file. Allergan, Inc.
  • 8. VIVIT速 Vibrance 8-Week Clinical Trial Design An 8-week, randomized, double-blind, split-face study of VIVIT速 Vibrance used on one side of the face (also randomized) and a 4% HQ bleaching gel used on the other side of the face Expert grader evaluations were made at baseline and at 4 and 8 weeks Twenty-one women aged 20 to 75 years with moderate pigmentation of the face participated in the trial; 18 (86%) completed the study No patients dropped out of the clinical trial due to irritation McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
  • 9. VIVIT速 Vibrance Helped Improve the Appearance of Fine Lines/Wrinkles, Skin Roughness, and Hyperpigmentation After 8 Weeks of Treatment Expert Evaluator 100 90 N=21 Percent Improvement 80 70% 70 66% 63% 61% 60 50 40 30 27% 27% 20 10 0 Fine Lines/Wrinkles Roughness Hyperpigmentation Natural-based Bleaching Cream 4% HQ Gel McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
  • 10. VIVIT速 Vibrance Helped Improve Hyperpigmentation After 8 Weeks of Treatment Processed UV RBX Brown (hyperpigmentation) Baseline Week 8 Baseline Week 8 Photos are completely untouched. Individual results may vary. McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
  • 11. Summary Topical aesthetics can be used to help improve the appearance of skins condition alone or in conjunction with other procedures VIVIT速 is an advanced glycolic and natural antioxidant system that helps improve the appearance of mild to moderate photodamaged skin in as few as 3 weeks1,2 VIVIT速 Skin Care Products are developed with proprietary GLX Technology* which is designed to help act as a vehicle for the deep penetration of glycolic acid bound to natural antioxidants VIVIT速 Vibrance is a natural hydroquinone-free agent for skin brightening and even skin tone VIVIT速 Vibrance helped improve the appearance of fine lines and wrinkles, skin roughness, and hyperpigmentation after 8 weeks of treatment3 *GLX Technology is owned by Pharma Cosmetix Research, LLC. 1. Data on file. Allergan, Inc.; 2. Downie JB. Cosmet Dermatol. 2008;21:168-175; 3. McDaniel DH, Wu J. Cosmet Dermatol. 2008;21:596-602.
  • 12. Allergan Supports the Pillars of Successful Practice Patient loyalty and practice growth Industry- Familiarity, Patient Practice leading trust, and satisfaction building products confidence APC72LJ10 息2010 Allergan, Inc. 速 and marks owned by Allergan, Inc.

Editor's Notes

  • #3: Topical aesthetics play an important role in the practice, both alone and in conjunction with other procedures Topical aesthetics can be used to help protect or improve the skins condition before other aesthetic procedures and can help complement results when used after procedures The aesthetic improvements offered by topical aesthetics may translate into greater interest in more advanced procedures, such as dermal fillers or facial injectables
  • #4: VIVIT 速 is an advanced glycolic and natural antioxidant system that helps improve the appearance of mild to moderate photodamaged patients in as few as 3 weeks Advanced skin care system designed with GLX Technology * Helps improve the appearance of mild to moderate photodamaged skin For all skin care patients For patients who are dissatisfied with their current skin care system Appropriate for all skin types (universal anti-aging system)
  • #5: VIVIT 速 Skin Care Products are formulated to address common skin care issues These products can be used separately or in combination, depending on the patients unique skin care needs The new VIVIT 速 Skin Care Products line introduces the GLX Technology antioxidant system
  • #6: GLX Technology helps facilitate a deep penetration and extended release of glycolic acid Partial neutralization allows the use of high concentrations of glycolic acid with reduced skin irritation
  • #7: The VIVIT 速 skin care routine is clinically proven to help improve moderately photodamaged skin Twenty-four women between the ages of 35 and 55 years with rough, dry facial skin, fine lines, and wrinkles from photodamage completed 3 weeks of treatment with the VIVIT 速 routine After 3 weeks, an independent expert reviewer assessed the results: 22% reduction in fine lines and wrinkles 36% increase in skin hydration/moisture content (mean value of suborbital and cheek areas) 54% improvement in skin smoothness 65% decrease in skin dryness