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Anesthetics drug
By
Muhammad Akbar
Rashid Qadri
(Vision Scientist, ounder of
Optometry club)

Aims and objective;
 What are anesthetics drugs?
 What are their composition?
 What are their types?
 what are their mechanism?
 Ophthalmic uses
 Adverse reaction
 Question answer section?

Anesthetics drugs

The drugs which
are used to
anesthesia the
body are called
anesthetics
drugs.

Composition
o Bascially they are tertiary
amines.
 They consist of following
components.
Aromatic lipophilic portion
Alkyl chain
Hydrocarbon chain

Types
Anesthetics
General
Anesthetic
s
Local
Anesthetics

Mechanism of action
 Exact mechanism of action is
unknown but they show their
action by;
Prevent nerve generation
Prevent the nerve conduction
Slow nerve propagation

Onset of Action
 It depend upon;
 lipid solubility
 PH of solution
 Protein binding
 Molecular size
 Dissociation constant

Drugs Available
Local Anesthetics
• Cocaine
• Tetracaine
• Procaine
• Benoxinate
Ester
group
• Mepivacaine
• Bupivacaine
• Lidocaine
Amide
group

Ophthalmic uses
o Tonometry
o ERG
o Contact lens fitting
o Minor surgery
o Forced duction testing
o Foreign body removal

Adverse Reaction
 Coma
 Decreased blood pressure
 Respiratory arrest
 Vasoconstriction
 Decreased cardiac output
 CNS depression

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