Anesthetic drugs
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The document discusses anesthetic drugs, including their composition, types, mechanisms of action, and ophthalmic uses. Anesthetics, primarily tertiary amines, prevent nerve generation and conduction, and their effectiveness depends on factors like lipid solubility and pH. Adverse reactions may include severe conditions like coma and respiratory arrest.
Anesthetic drugs
- 1. Anesthetics drug By Muhammad Akbar Rashid Qadri (Vision Scientist, ounder of Optometry club)
- 2. Aims and objective; What are anesthetics drugs? What are their composition? What are their types? what are their mechanism? Ophthalmic uses Adverse reaction Question answer section?
- 3. Anesthetics drugs The drugs which are used to anesthesia the body are called anesthetics drugs.
- 4. Composition o Bascially they are tertiary amines. They consist of following components. Aromatic lipophilic portion Alkyl chain Hydrocarbon chain
- 6. Mechanism of action Exact mechanism of action is unknown but they show their action by; Prevent nerve generation Prevent the nerve conduction Slow nerve propagation
- 7. Onset of Action It depend upon; lipid solubility PH of solution Protein binding Molecular size Dissociation constant
- 8. Drugs Available Local Anesthetics Cocaine Tetracaine Procaine Benoxinate Ester group Mepivacaine Bupivacaine Lidocaine Amide group
- 9. Ophthalmic uses o Tonometry o ERG o Contact lens fitting o Minor surgery o Forced duction testing o Foreign body removal
- 10. Adverse Reaction Coma Decreased blood pressure Respiratory arrest Vasoconstriction Decreased cardiac output CNS depression