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Antibacterial sulphonamides

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Indrajeet Singh
Indrajeet Singh

ANTIBACTERIAL SULPHONAMIDES DRUGS..

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ANTIBACTERIAL SULPHONAMIDES SULPHONAMIDES ARE ANTIBACTERIAL SUBSTANCE WITH A SULPHONAMIDO (So2NH2) GROUP. SULPHANILAMIDE IS THE SIMPLEST OF SULPHONAMIDES.
ALL SULPHONAMIDES MAY BE CONSIDER TO BE DERIVTAIVES OF SULPHANILAMIDES WHICH IS P- aminobenzene sulphonamide H2N SO2NH2 SULPHANILAMIDE
CLASSIFICATION A. CHEMICAL CLASSIFICATION A) N1 SUBSTITUDED SULPHONAMIDES : -- 1. SULPHACETAMIDE 2. SULPHAGUANIDINE 3. SULPHADIAZINE 4. SULPHATHIAZOLE 5. SULPHADIMETHOXINE 6. SULPHAFURAZOLE 7. SULPHAMETHOXAZOLE 8. SULPHAMERAZINE 9. SULPHAMETHAZINE 10. SULPHASOMIDINE 11. SULPHAMETHOXINE 12. SULPHADOXINE
N1 AND N4 SUBSTITUTED SULPHONAMIDES 1. Succinylsulphathiazole 2. Phthalylsulphathiazole N4 SUBSTITUTED SULPHONAMIDES:-- Prontosil SULPHONAMIDES WITHOUT AROMATIC AMINO GROUP:-- Mefinide
2. Pharmacological classification SULPHONAMIDES USED IN INTESTINAL INFECTION:-- Sulphaguanidine Succinylsulphathiazole Phthalylsulphathiazole SULPHONAMIDES USED IN EYE INFECTION:- Sulphacetamide
SULPHONAMIDES IS USED IN SYSTEMIC INFECTION:-- SULPHADIZINE SULPHATHIAZOLE SULPHADIMETHOXINE SULPHAPHENAZOLE SULPHAFURAZOLE SULPHAMETHOXAZOLE SULPHAMERAZINE SULPHAMETHAZINE SULPHASOMADINE SULPHADIMETHOXINE SULPHADOXINE
SULPHONAMIDE USED IN URINARY INFECTION:-- Sulphafurazole Sulphaphenazole 3. CLASSIFICATION BASED ON DURATION OF ACTION:-- *SHORT ACTING (4 to 8 hours) Sulphadizine Sulphathiazole Sulfisoxazole sulphadizine sulphamerazine Sulphamethazine Sulphasomidine sulphamethizole
Antibacterial sulphonamides
Antibacterial sulphonamides

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Antibacterial sulphonamides

  • 1. ANTIBACTERIAL SULPHONAMIDES SULPHONAMIDES ARE ANTIBACTERIAL SUBSTANCE WITH A SULPHONAMIDO (So2NH2) GROUP. SULPHANILAMIDE IS THE SIMPLEST OF SULPHONAMIDES.
  • 2. ALL SULPHONAMIDES MAY BE CONSIDER TO BE DERIVTAIVES OF SULPHANILAMIDES WHICH IS P- aminobenzene sulphonamide H2N SO2NH2 SULPHANILAMIDE
  • 3. CLASSIFICATION A. CHEMICAL CLASSIFICATION A) N1 SUBSTITUDED SULPHONAMIDES : -- 1. SULPHACETAMIDE 2. SULPHAGUANIDINE 3. SULPHADIAZINE 4. SULPHATHIAZOLE 5. SULPHADIMETHOXINE 6. SULPHAFURAZOLE 7. SULPHAMETHOXAZOLE 8. SULPHAMERAZINE 9. SULPHAMETHAZINE 10. SULPHASOMIDINE 11. SULPHAMETHOXINE 12. SULPHADOXINE
  • 4. N1 AND N4 SUBSTITUTED SULPHONAMIDES 1. Succinylsulphathiazole 2. Phthalylsulphathiazole N4 SUBSTITUTED SULPHONAMIDES:-- Prontosil SULPHONAMIDES WITHOUT AROMATIC AMINO GROUP:-- Mefinide
  • 5. 2. Pharmacological classification SULPHONAMIDES USED IN INTESTINAL INFECTION:-- Sulphaguanidine Succinylsulphathiazole Phthalylsulphathiazole SULPHONAMIDES USED IN EYE INFECTION:- Sulphacetamide
  • 6. SULPHONAMIDES IS USED IN SYSTEMIC INFECTION:-- SULPHADIZINE SULPHATHIAZOLE SULPHADIMETHOXINE SULPHAPHENAZOLE SULPHAFURAZOLE SULPHAMETHOXAZOLE SULPHAMERAZINE SULPHAMETHAZINE SULPHASOMADINE SULPHADIMETHOXINE SULPHADOXINE
  • 7. SULPHONAMIDE USED IN URINARY INFECTION:-- Sulphafurazole Sulphaphenazole 3. CLASSIFICATION BASED ON DURATION OF ACTION:-- *SHORT ACTING (4 to 8 hours) Sulphadizine Sulphathiazole Sulfisoxazole sulphadizine sulphamerazine Sulphamethazine Sulphasomidine sulphamethizole