anticoagulant pre defense
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This document discusses a study determining the anticoagulant property of the ethanolic extract of Makabuhay (Tinospora rumphii Boerl). The study aims to provide an alternative natural treatment for cardiovascular diseases to reduce risks of current anticoagulant medications and costs. Researchers will assess anticoagulant effects of Makabuhay extracts in vitro using activated partial thromboplastin time and prothrombin time clotting assays, and in vivo using a mouse tail bleeding time test. Results could offer a potential natural anticoagulant and help reduce cardiovascular disease burden.
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An ancient System for holistic health (mental and physical) and wellbeing, is a scientific art of living with harmony (connecting) of mind and body. Although much more ancient than Patanjali, who documented yoga systematically about 2000 years ago, Patanjali is often referred to as the "father of modern yoga."
Yoga postures are commonly depicted in ancient paintings, carvings, and sculptures in almost all civilizations and religions, thus Yoga cant be described as an act of Hinduism. It originated long before any religion on Earth, with the emergence of life on the Planet. All yoga poses are natural, and what is not natural is not yoga; it is油Viyoga.
Besides Vedic Yoga, Hatha, Vinyasa, Ashtanga, Iyengar, Yin, Restorative, Kundalini, Bikram, Sahaj, and Power yoga are some popular types.
Vinyasa油Yoga is the closest form to Vedic Yoga; it is known for its flowing movements, not very rigorous, not too much straining, actions flow with the breath.
Though all yoga may lead to meditation (Dhyan) for your inner upliftment, it is not the same as described in Hinduism for self-liberation.
In Hinduism, different paths of life looking distinct but can be practiced all together, they are: Karma Yoga (selfless action and service), Bhakti Yoga (devotion and love for God or Godly power), Jnana (Gyan) Yoga (gaining knowledge for self-realization through wisdom), Dhyan Yoga (meditation) and Kriya Yoga (optimum utilization of your vital and muscular energy).油
Theories of Learning and Teaching.......
Theories of Learning and Teaching.......Avantika Gupta
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Definition of Teaching:
Teaching is a form of interpersonal influence aim at changing the behavior potential of another person.
Nature and Characteristics of Teaching:
Teaching is giving information.
Teaching is causing to learn.
Teaching is a matter of helping the child to respond to his environment in an effective manner.
Teaching is helping a child to adjust himself to his environment.
Teaching is stimulation and encouragement.
Teaching is guidance.
Teaching is Training the emotions of the child.
Teaching is a mean of preparation.
Teaching is an art and science.
General Theory of Teaching:
The General Theory of Teaching, also known as the "Theory of Teaching" or "General Theory of Instruction," is a comprehensive framework that outlines the fundamental principles and processes of teaching.
Benefits of the General Theory of Teaching:
Improved Student Learning
Increased Teacher Efficacy
Enhanced Teacher Professional Development
Better Student Engagement
CONCLUSION
Teaching theory is prescriptive.
Teachers and pupils are the major variables of teaching theory.
It is narrow and specific.
It is based upon learning theory, learning conditions and learning components.
While learning theory are formulated by conducting experiments on animals teaching theory is developed by dealing with human subjects in normal situations.
It is concerned with effective learning and development of pupils.
Learning is a complex and multifaceted process that involves the acquisition, processing, and retention of knowledge, skills, and attitudes.
The relatively permanent change in a person's knowledge or behavior due to experience.
Characteristics of Learning:
Learning is Growth.
Learning is adjustment.
Learning is purposeful.
Learning is intelligent.
Learning is active.
Learning is both individual and social.
Learning is the product of the environment.
Learning is experience.
Learning Theory: Learning theory refers to the body of knowledge that explains how people learn and acquire new knowledge, skills, and attitudes.
Types of Teaching Theory:
1.Formal Theory of Teaching
Meutic Theory of teaching.
Communication theory of teaching.
Moulding theory of teaching.
The mutual enquiry theory.
2.Descriptive theory of teaching
Theories of instruction
Prescriptive theory of teaching
3.Normative theory of teaching
Cognitive theory of teaching
Theory of teacher behaviour
Psychological theory of teaching
General theory of teaching
FORMAL THEORY OF TEACHING
Formal theory of teaching is also known as philosophical theory. The theory which is based upon certain logic, certain metaphysical, epistemological assumptions and propositions is known as formal theory of teaching.
1.Meutic Theory of Teaching:
This theory conceives that teaching process helps to recollect or unfold that knowledge with questioning techniques.
The Socratics method is an essential for this theory.
The heredity plays an importUpdates_in Head__Neck TNM staging- 9th edition.pptx
Updates_in Head__Neck TNM staging- 9th edition.pptxDr. Maroti Wadewale
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The Union for International Cancer Control (UICC) and the American Joint Committee on Cancer (AJCC) collaborate closely to produce the globally recognized TNM Classification of Malignant Tumours. Therefore, when discussing the "9th edition of UICC head and neck staging," it's largely in alignment with the updates introduced by the AJCC's Version 9. The UICC's TNM Core Committee finalized the 9th edition of the TNM Classification, with publication anticipated in August 2025.
The key updates for head and neck cancers in the 9th edition (or Version 9) reflect an ongoing effort to improve prognostic accuracy and align staging with contemporary clinical understanding and treatment outcomes. Here are the significant changes, particularly those relevant to head and neck:
* Emphasis on Personalized Care and Prognostic Refinements: The 9th edition reflects a greater focus on personalized care, incorporating refinements that aim to better predict patient outcomes.
* Revised Criteria for Specific Head and Neck Cancers:
* Nasopharyngeal Carcinoma (NPC): This site has seen substantial revisions, as highlighted in the previous response on AJCC updates. Key changes include:
* More precise definition of T3 disease (unequivocal evidence of bone involvement).
* Introduction of advanced radiologic extranodal extension (ENE) as an N3 criterion. This acknowledges the prognostic impact of ENE seen on imaging.
* Subclassification of M1 disease into M1a (3 or fewer metastatic lesions) and M1b (more than 3 lesions) to better stratify prognosis in metastatic settings.
* Redefined Stage Groups for NPC, with T1-2N0-1 now often falling into Stage I, and Stage IV being exclusively for metastatic disease, further subdivided by the M1a/M1b categories.
* Salivary Gland Cancers: Revised criteria based on updated imaging and anatomical features are being incorporated.
* HPV-Related Oropharyngeal Cancers: New staging is introduced for HPV-associated oropharyngeal cancers to better reflect their distinct biological behavior and prognosis, which is generally more favorable than HPV-negative oropharyngeal cancers. This often involves specific considerations for nodal burden.
* Integration of Imaging and Anatomical Features: The updates are grounded in recent evidence, incorporating insights from advanced imaging techniques and a deeper understanding of anatomical spread.
* International Collaboration: These updates are the result of collaborative efforts between the AJCC and UICC, involving input from cancer registries, clinical outcomes data, and disease-specific experts worldwide. The goal is to provide a unified and globally applicable staging system.
* Dynamic Update Process: Similar to the AJCC's shift from "Editions" to "Versions" for specific sites, the UICC is also exploring more flexible ways to share future TNM updates.
In essence, the 9th edition of the UICC staging system for head and neck cancers, particularly in areas like NPC and HPVSelf-Awareness and Self-Care How Professionals Can Avoid Burnout
Self-Awareness and Self-Care How Professionals Can Avoid BurnoutOlaf Kraus de Camargo
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Closing Keynote at the IV OGLNOPOLSKA KONFERENCJA & WARSZTATY
KomunikAACja, Samoswiadomosc, Seksualnosc
June 13th 14th, 2025
An overview of the definition and presentation of burnout in healthcare workers, strategies to prevent it and to build resilience. The presentation also explores the barriers and enablers to introducing wellness strategies in organizations.nanoparticle and liposomes ppt .(NTDS)pdf
nanoparticle and liposomes ppt .(NTDS)pdfsiddhikalbande
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Nanoparticles and liposomes are advanced carriers used for targeted drug delivery.
Nanoparticles enhance drug effectiveness by directing treatment to specific sites.
Liposomes are biocompatible vesicles that enable controlled and sustained drug release.Growth hormone by Dr Kondam AmbareeshaGoud
Growth hormone by Dr Kondam AmbareeshaGoudDr K Ambareesha Goud PhD
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Growth hormone (GH) secretion from anterior pituitary is regulated by the hypothalamus and the mediators of GH actions. Major regulatory factors include GH releasing hormone (GHRH), somatostatin (SRIF), GH releasing peptide (ghrerin) and insulin-like growth factor (IGF-I).AD-SAFE: An Initiative to Build Understanding of ARIA and Skills Needed to Gu...
AD-SAFE: An Initiative to Build Understanding of ARIA and Skills Needed to Gu...PVI, PeerView Institute for Medical Education
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Chair and Presenter, Ana M. Franceschi, MD, PhD, and Petrice M. Cogswell, MD, PhD, discuss Alzheimers disease in this CME/MOC/NCPD/CPE/AAPA/IPCE activity titled AD-SAFE: An Initiative to Build Understanding of ARIA and Skills Needed to Guide Treatment Decisions and Support Rapid Recognition and Response in Radiology. For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/42nd09H. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until May 26, 2026.Pharmaceutical Agents Acting on the Gastrointestinal Tract (GIT)
Pharmaceutical Agents Acting on the Gastrointestinal Tract (GIT)Sajini
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This presentation provides a detailed overview of gastrointestinal (GIT) agents used in pharmaceutical practice, including antacids, acidifying agents, cathartics, protectives, and adsorbents. It covers classification, mechanisms, properties, uses, and common brand names. Ideal for pharmacy students and healthcare professionals.5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...
5-Lift Analysis in ergonomics focuses on evaluating the safety and efficienc...Bolan University of Medical and Health Sciences ,Quetta
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Unlocking the Potential of Long-Acting PrEP to Halt HIV Transmissions
Unlocking the Potential of Long-Acting PrEP to Halt HIV TransmissionsPVI, PeerView Institute for Medical Education
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AD-SAFE: An Initiative to Build Understanding of ARIA and Skills Needed to Gu...
AD-SAFE: An Initiative to Build Understanding of ARIA and Skills Needed to Gu...PVI, PeerView Institute for Medical Education
油
Ad
anticoagulant pre defense
- 1. MANABAT, Alyssa Faye V. Determination of The Anticoagulant Property of The Ethanolic Extract of The Medicinal Stem of Makabuhay ( Tinospora rumphii Boerl) MICLAT, Patricia Bianca A. NAGUIAT, Cristel Ann I. PALMARES, Maylene B. PARIO, Kathleen M. SANDERS-CAPAROSO, Alliet Kita BSPH4Y1-1 The ResearchersResearch Adviser Ms. Mariel Ni単a Esguerra, RPh
- 2. Ischemic heart disease Stroke 15.2 million Deaths in 2016
- 3. A c t i v a t i o n o f P l a t e l e t s V a s o c o n s t r i c t i o n Mechanism of Coagulation I n j u r y t o E n d o t h e l i u m F o r m a t i o n o f a b l o o d c l o t Extrinsic Pathway Intrinsic Pathway 01 Prothrombin to Thrombin 03 Fibrinogen to Fibrin 04 Blood clotting factors 02 Coagulation
- 4. www.presentationgo.com Heart Attack Ischemic Heart Disease Stroke Cerebrovascular disesase Venous Thromboembolism Deep Vein Thrombosis Pulmonary embolism
- 5. www.presentationgo.com Treatment Arterial and venous thrombotic disorders Cardiovascular diseases Prevention Treatment Cardiovascular diseases Cerebrovascular diseases 3 1 2 Anticoagulants Long term prevention of recurrences Prevent the occurrence or increase of unwanted clots Vit. K Antagonist Warfarin Direct thrombin inhibitors Hirudin Dabigatran Argatrroban Bivalirudin Pentasaccharide Anticoagulants Fondaparinux Natural thrombin inhibitor Heparin Antiplatelets Aspirin Clopidogrel Prasugrel >>>>>>>>> >>>>>>>>> Major Causes of Death 1 Medication Risks of Present-day Anticoagulants 2 Cost3
- 6. Makabuhay (Tinospora rumphii Boerl) Menispermaceae Climbing vine Widely distributed in Southeast Asia (Philippines) Used in traditional medicine As anticoagulant DITERPENES
- 7. SIGNIFICANCE OF THE STUDY It will help the community by giving them an alternative way to treat and prevent cardiovascular diseases with the use of natural resources. It will reduce the use of synthetic drugs. It will give knowledge to the students about the natural ways of treatment and prevention of cardiovascular diseases. It will help the manufacturers on the production of medicine without the use of synthetic It will serve as references.
- 8. about history timelin e teams service s follow HEADINGYOU CAN ADD SOME BRIEF TEXT HERE 2014 HEADINGYOU CAN ADD SOME BRIEF TEXT HERE 2015 HEADINGYOU CAN ADD SOME BRIEF TEXT HERE 2016
- 9. www.presentationgo.com Bioassay 1 2 3 Acute toxicity In Vitro In Vitro
- 10. www.presentationgo.com In Vitro Assay Note aPTT clotting time Incubate for 3 minutes at 37属C 50 疋L APTT reagent 100 疋L plant extract 50 疋L normal citrated PPP 100 疋L of CaCl (20mM) Activated Partial Thromboplastin Time (aPTT) Mus muculus Retroorbital 100 疋L of PT reagent Incubate for 3 minutes at 37属C 50 疋L plant extract 50 疋L normal citrated PPP Note PT clotting time Prothrombin Time (PT)
- 11. www.presentationgo.com In Vivo Assay Tail Bleeding Time Mus muculus 321 Dabigatran etexilate (20mg/kg) Oral administration for 4 consecutive days 90mins after last admin, mark the tail (5mm) and cut Immerse the tip of the tail in saline at 37属C. Note bleeding time. 1st concentration 54 2nd 3rd Oral administration for 4 consecutive days 90mins after last admin, mark the tail (5mm) and cut Immerse the tip of the tail in saline at 37属C. Note bleeding time. Control (NSS) Oral administration for 4 consecutive days 90mins after last admin, mark the tail (5mm) and cut Immerse the tip of the tail in saline at 37属C. Note bleeding time. Oral administration for 4 consecutive days 90mins after last admin, mark the tail (5mm) and cut Immerse the tip of the tail in saline at 37属C. Note bleeding time. Oral administration for 4 consecutive days 90mins after last admin, mark the tail (5mm) and cut Immerse the tip of the tail in saline at 37属C. Note bleeding time.
- 12. References: Ahmad, W., Jantan, I., Bukhari SNA. (2016). Tinospora crispa (L.) Hook. F. & Thomson: A Review of Its Ethnobotanical, Phytochemical and Pharmacological Aspects. Frontiers in pharmacology. doi:10.3389/fphar.2016.00059 Chen, H., Jin, M., Wang, Y., Wang, Y.Q., Meng, L., Li, R., Ping, J., Li, G., Kong, Y., & Wei, J. (2014). Effect of Toona microcarpa Harms Leaf extract on the Coagulation System. http://dx.doi.org/10.1155/2014/615363 Felix-Silva, J., Souza, T., Camara, R.B.B.G., et. al BMC Complement Altern Med (2014) In vitro anticoagulant and antioxidant activities of Jatropha gossypiifolia L. (Euphorbiaceae|) leaves aiming therapeutical applications 14: 405. https://doi.org/10.1186/1472-6882-14-405