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App processing and plaque formation creative diagnostics

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Creative-Diagnostics

Excess amyloid β-peptide is believed to be a main contributor to the dysfunction and degeneration of neurons that occurs in Alzheimer’s disease. Aβ is a 38 to 43 amino acid peptide that is derived from the β amyloid precursor protein, APP.

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CD Creative Diagnostics ® CD Creative Diagnostics ® APP Processing and Plaque Formation
CD Creative Diagnostics ® CD Creative Diagnostics ® APP Aβ Aβ Plaque Neuronal dysfunction & degeneration Alzheimer’s disease
CD Creative Diagnostics ® CD Creative Diagnostics ® APLP1APLP2APP TM domain N-terminal C-terminal Aβ APP superfamily protein family
CD Creative Diagnostics ® CD Creative Diagnostics ® 90% 10% APP processing Amyloidogenic Pathway Amyloid Plaque Formation Canonical Pathway Non-amyloidogenic APPCleared
CD Creative Diagnostics ® CD Creative Diagnostics ® The non-amyloidogenic pathway APPC83CTF P3 sAPPα γ-secretase α-secretase Aβ
CD Creative Diagnostics ® CD Creative Diagnostics ® The Amyloidogenic Pathway APP C99 AICD sAPPβ γ-secretase β-secretase Aβ Aβ
CD Creative Diagnostics ® CD Creative Diagnostics ® The Amyloidogenic Pathway Endosom e Aβ Aβ Plaque Aβ oligomer
CD Creative Diagnostics ® CD Creative Diagnostics ® Aβ 1-42 Structure of Aβ1-40 Structure of Aβ1-42 VS.
CD Creative Diagnostics ® CD Creative Diagnostics ® www.creative-diagnostics.com 45-1 Ramsey Road, Shirley, NY 11967, USA info@creative-diagnostics.com APP processing │

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App processing and plaque formation creative diagnostics