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arNOX
DISCOVERY
OUR
SCIENCE
YOUR
SECRET
HAVE YOU EVER WONDERED
WHY SOME PEOPLE
LOOK YOUNGEROR OLDER
THAN THEIR ACTUAL AGE?

NU SKIN HAS THE ANSWER.


IN YOUR YOUTHFUL TWENTIES YOUR SKIN PRODUCES ABUNDANT
amounts of collagen and elastinthe skins structural proteins responsible
for 鍖rm, smooth, resilient skin. But as you age, continuous exposure to
free radicals in鍖icts damage on these proteins and reduces their production
in the body, causing the skin to wrinkle and sag.
Most of us know its important to protect our skin from the dangerous,
skin damaging effects of the sun and environment, and we use the latest
skin care technologies to try to repair and prevent signs of aging. So why
do some of us still appear to age faster than we think we should?
In a revolutionary skin care breakthrough, Nu Skin has unlocked the science
behind the secret of why some people seem to look younger longer.
Arnox brochure
REVOLUTIONARY DISCOVERY
THE arNOX ENZYME



                                          SKIN DAMAGING
                                          FREE RADICALS




                                              arNOX ENZYME




NEW RESEARCH BY DRS. JAMES AND DOROTHY MORR HAS IDENTIFIED
a major, previously undiscovered source of aging within each of us: an internal free
radical generator in the epidermisthe arNOX enzyme. And our genes control its
activity, which increases as we age. Present on the surface of our cells, this invisible
enemy is capable of generating skin damaging free radicals around the clock that
can destroy collagen and elastin. The result? Looking years older than you already are.
SERUM arNOX CORRELATES WITH AGE

          SUPEROXIDE PRODUCTION (arNOX ACTIVITY) MEASURED AS
             FERRICYTOCHROME C REDUCTION, NMOLES/MIN/ML




DURING A STUDY CONDUCTED AT PURDUE UNIVERSITY, SCIENTISTS
discovered that arNOX levels correlate with chronological age and that arNOX
activity starts to increase during the aging years, beginning sometime during
the mid-thirties. Scientists also concluded that a persons arNOX activity is not
triggered by sun exposure, providing further evidence that increased arNOX
activity is an identi鍖ed source of biological aging.

UNLIKE THE SUN, YOU CAN'T HIDE FROM arNOX. BUT NOW YOU CAN SLOW ITS
arNOX=LOOKING YOUNGER OR OLDER
     IN A STUDY CONDUCTED AT STANFORD UNIVERSITY, RESULTS INDICATED
     that people with high levels of this aging enzyme can appear older than their
     biological age, while those with low levels can appear younger.


                    HIGH arNOX LEVEL                       +18                          STANFORD
                                                           +16                          STUDY SHOWS
                                                           +14                          Individuals with high



                                      7
                                                           +12
                                                                                        levels of arNOX appear
                        AVERAGE OF     YEARS   OLDER       +10
                                                            +8                          to be an average of seven




                                                                  ACTUAL AGE IN YEARS
                                                            +6                          years older than their
                                                            +4
      arNOX LEVEL




                                                            +2                          actual age.




                                      7
                                                             -2                         Individuals with low
                        AVERAGE OF     YEARS   YOUNGER       -4
                                                             -6
                                                             -8
                                                                                        arNOX levels are clinically
                                                                                        graded to look an
                                                            -10                         average of seven years
                                                            -12
                                                            -14                         younger than their actual
                                                            -16                         chronological age.
                                                            -18
                    LOW arNOX LEVEL



     EVIDENCE OF arNOX IN THE SKIN PROVIDES FURTHER INSIGHTS INTO POTENTIALLY R
     because its activity correlates with the ages when people begin to see their skin lose its elas
     wrinkles. If we can develop innovative ways to inhibit arNOX activity and prevent the produc
     sides of the equationcorrecting free radical damage from external sources, while at the sam
     HELEN KNAGGS, PH.D., VICE PRESIDENT OF NU SKIN GLOBAL RESEARCH AND DEVELOPMENT




S DAMAGING EFFECTS. FOR MORE INFORMATION, VISIT WWW.AGELOC.COM.
SLOW THE SOURCE
           NU SKIN SCIENTISTS TESTED INGREDIENTS THAT WOULD HELP PREVENT
           the expression of free radicals associated with the arNOX enzyme. This
           prevention may help us develop ways to slow the signs of aging that come
           from accelerated free radical production.
                               APPLIED arNOX INHIBITOR INGREDIENT




                                                                                        This experiment shows
             arNOX Activity




                                                                                        how an in vitro ar NOX
                                                                                        inhibitor can block ar NOX
                                                                                        enzyme activity and
                                                                                        production of damaging
                                                                                        free radicals.


                                                Time
                 arNOX ACTIVITY measured in vitro through FERRICYTOCHROME C REDUCTION
                                       nmoles/min/1.5 mg epidermis



Y REVOLUTIONARY THERAPIES FOR SKIN CARE, PARTICULARLY
lasticity and 鍖rmness, and notice more discoloration and lines and
duction of free radicals in the 鍖rst place, then we can address both
ame time preventing free radical production from internal sources.
息 2009 Nu Skin Enterprises, Inc.
75 West Center Street, Provo, UT 84601
1-800-487-1000  www.nuskin.com

01007073      US 5PK



息 2009 Nu Skin Canada, Inc.
3350 Ridgeway Drive, Unit #1
Mississauga, Ontario, Canada, L5L 5Z9
1-800-877-6100  www.nuskin.com/canada

02007073      CA 5PK

More Related Content

Arnox brochure

  • 2. HAVE YOU EVER WONDERED WHY SOME PEOPLE LOOK YOUNGEROR OLDER THAN THEIR ACTUAL AGE? NU SKIN HAS THE ANSWER. IN YOUR YOUTHFUL TWENTIES YOUR SKIN PRODUCES ABUNDANT amounts of collagen and elastinthe skins structural proteins responsible for 鍖rm, smooth, resilient skin. But as you age, continuous exposure to free radicals in鍖icts damage on these proteins and reduces their production in the body, causing the skin to wrinkle and sag. Most of us know its important to protect our skin from the dangerous, skin damaging effects of the sun and environment, and we use the latest skin care technologies to try to repair and prevent signs of aging. So why do some of us still appear to age faster than we think we should? In a revolutionary skin care breakthrough, Nu Skin has unlocked the science behind the secret of why some people seem to look younger longer.
  • 4. REVOLUTIONARY DISCOVERY THE arNOX ENZYME SKIN DAMAGING FREE RADICALS arNOX ENZYME NEW RESEARCH BY DRS. JAMES AND DOROTHY MORR HAS IDENTIFIED a major, previously undiscovered source of aging within each of us: an internal free radical generator in the epidermisthe arNOX enzyme. And our genes control its activity, which increases as we age. Present on the surface of our cells, this invisible enemy is capable of generating skin damaging free radicals around the clock that can destroy collagen and elastin. The result? Looking years older than you already are.
  • 5. SERUM arNOX CORRELATES WITH AGE SUPEROXIDE PRODUCTION (arNOX ACTIVITY) MEASURED AS FERRICYTOCHROME C REDUCTION, NMOLES/MIN/ML DURING A STUDY CONDUCTED AT PURDUE UNIVERSITY, SCIENTISTS discovered that arNOX levels correlate with chronological age and that arNOX activity starts to increase during the aging years, beginning sometime during the mid-thirties. Scientists also concluded that a persons arNOX activity is not triggered by sun exposure, providing further evidence that increased arNOX activity is an identi鍖ed source of biological aging. UNLIKE THE SUN, YOU CAN'T HIDE FROM arNOX. BUT NOW YOU CAN SLOW ITS
  • 6. arNOX=LOOKING YOUNGER OR OLDER IN A STUDY CONDUCTED AT STANFORD UNIVERSITY, RESULTS INDICATED that people with high levels of this aging enzyme can appear older than their biological age, while those with low levels can appear younger. HIGH arNOX LEVEL +18 STANFORD +16 STUDY SHOWS +14 Individuals with high 7 +12 levels of arNOX appear AVERAGE OF YEARS OLDER +10 +8 to be an average of seven ACTUAL AGE IN YEARS +6 years older than their +4 arNOX LEVEL +2 actual age. 7 -2 Individuals with low AVERAGE OF YEARS YOUNGER -4 -6 -8 arNOX levels are clinically graded to look an -10 average of seven years -12 -14 younger than their actual -16 chronological age. -18 LOW arNOX LEVEL EVIDENCE OF arNOX IN THE SKIN PROVIDES FURTHER INSIGHTS INTO POTENTIALLY R because its activity correlates with the ages when people begin to see their skin lose its elas wrinkles. If we can develop innovative ways to inhibit arNOX activity and prevent the produc sides of the equationcorrecting free radical damage from external sources, while at the sam HELEN KNAGGS, PH.D., VICE PRESIDENT OF NU SKIN GLOBAL RESEARCH AND DEVELOPMENT S DAMAGING EFFECTS. FOR MORE INFORMATION, VISIT WWW.AGELOC.COM.
  • 7. SLOW THE SOURCE NU SKIN SCIENTISTS TESTED INGREDIENTS THAT WOULD HELP PREVENT the expression of free radicals associated with the arNOX enzyme. This prevention may help us develop ways to slow the signs of aging that come from accelerated free radical production. APPLIED arNOX INHIBITOR INGREDIENT This experiment shows arNOX Activity how an in vitro ar NOX inhibitor can block ar NOX enzyme activity and production of damaging free radicals. Time arNOX ACTIVITY measured in vitro through FERRICYTOCHROME C REDUCTION nmoles/min/1.5 mg epidermis Y REVOLUTIONARY THERAPIES FOR SKIN CARE, PARTICULARLY lasticity and 鍖rmness, and notice more discoloration and lines and duction of free radicals in the 鍖rst place, then we can address both ame time preventing free radical production from internal sources.
  • 8. 息 2009 Nu Skin Enterprises, Inc. 75 West Center Street, Provo, UT 84601 1-800-487-1000 www.nuskin.com 01007073 US 5PK 息 2009 Nu Skin Canada, Inc. 3350 Ridgeway Drive, Unit #1 Mississauga, Ontario, Canada, L5L 5Z9 1-800-877-6100 www.nuskin.com/canada 02007073 CA 5PK