Arthritis
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Arthritis is a common problem in winter and in the daily lives of many across the globe. Presenting here few natural medicine for healing and relief from painful moments
Arthritis
- 1. Presented by Dr. Sudhakar Kokate Director PPRC, India
- 2. About disease Inflammation of a joint characterised by pain, swelling and limitation of a joint movement Osteo-arthritia (OA) Knee and hipdebilitating disease affected More in women than male Increases with ageing PPRC/INDIA 01
- 3. About disease Rheumatoid arthritis (RA) - Most common disease - Affects 1% of world population - Involves many joints PPRC/INDIA 02
- 5. Drugs in Practice Non-steroidal anti-inflammatory drugs (NSAIDS) . For symptomatic treatment of OA and RA Side effects risk in use - many limitations PPRC/INDIA 04
- 6. Side effects of NSAIDS drugs Propensity to cause stomach ulcers - GI bleeding - Perforations New cox 2 drugs - Long term use may increase the risk of stroke and heart attack PPRC/INDIA 05
- 7. Side effects of NSAIDS drugs USFDA withdrawn from market Biologics drugs (Anti-bodies for IL-1, IL-6, TNF-) Benefits: - Reduce inflammation - Joint destruction PPRC/INDIA 06
- 8. Disadvantages Not effective universally Higher costs Severe side effects as life threatening infections Increases risk of malignances PPRC/INDIA 07
- 9. Emerging CAM therapy CAM: Complementary and Alternative Medicine Use of accu-puncture 60-90% of dissatisfied patients use this therapy PPRC/INDIA 08
- 10. Symptoms of Arthritis Caused due to the aggravation of vata (air) dosha and accumulation of Ama (toxins) gets deposited in the weak areas of the body Weak digestion, constipation, overeating and little physical activity PPRC/INDIA 09
- 11. Osteoarthritis Most common joint disease Women >55 yrs age affected 12% incidences of Osteoarthritis in India Condition of synovial joints characterised by cartilage loss with peri-articular response PPRC/INDIA 10
- 12. Emerging new trends in the development of PhytoDrugs In Arthritis PPRC/INDIA 11
- 14. Withania somnifera The root contains traces of an essential oil It is effective in the treatment of rheumatic infections The water soluble portion of the root extract contains indefinite amorphous substances and a quantity of sugar PPRC/INDIA 13
- 16. Trachyspermum ammi The seeds are used as a household remedy for indigestion, colic, diarrhoea, flatulence and asthma In arthritis it is quite effective Ref. The Ayurvedic Pharmacopoeia of India, New Delhi Part I, Vol. I, II Waltis T.E. - Textbook of Pharmacogney PPRC/INDIA 15
- 18. Medicago sativa It contains 1-canavanine, an amino acid causes curing properties against joint pain PPRC/INDIA 17
- 20. Angelica archangelica It is used in European folk medicine Western variety has 12 anti-inflammatory constituents, 10 anti-spasmodic constituents and 5 anodyne ones Chinese species is sold in North America in the name of dang guei or dang quai PPRC/INDIA 19
- 22. Cimicifuga racemosa There are five species worldwide that have been used to treat rheumatism It contains aspirin-like substances and the root of the plant is very beneficial Other anti-inflammatory and anti-spasmodic constituents PPRC/INDIA 21
- 24. Apium graveolens Eating raw or cooked celery seeds or large amount of this plant to treat rheumatism arrived in North America Celery is rich in minerals 1 cup of celery contains 350 mg of potassium PPRC/INDIA 23
- 26. Larrea tridentata It is widely promoted in health food-stores as a treatment for arthritis Externally as a wash or internally as a tea PPRC/INDIA 25
- 27. Cats claw Uncaria tomentosa, Uncaria guianensis PPRC/INDIA 26
- 28. Uncaria tomentosa, Uncaria guianensis This plant contains oxindole alkaloids tannis, quinoxic acid glycosides, flavonoids and sterols Extract of this herb is effective in arthritis PPRC/INDIA 27
- 30. Cedrus deodara It is acute and pungent in action This is one of the most useful drug It is used in combination with other anti-pyretics PPRC/INDIA 29
- 32. Panax quinquefolius It contains ginsenosides which has a variety of pharmacological actions It handles a wide variety of stresses effective in rheumatism PPRC/INDIA 31
- 34. Allium sativum It possesses anti-inflammatory anti-arthritic, hypolipidemic, anti-coagulant, hypo-proteomic, hypo- cholesterolemic, anti-bacterial, anti-fungal, antihypersensitive and hypo-glycaemic action PPRC/INDIA 33
- 36. Paederia foetida This plant exhibits disease modifying antirheumatic activity It also helps in treating inflammatory disorders PPRC/INDIA 35
- 38. Zingiber officinale Chromatographic fraction results showed that most of the fractions containing gingerols / gingerol derivatives were excellent inhibitors of LPS-induced PGE-2 production Ginger extract when administered daily for 4 weeks caused significant reduction in PGE-2 levels in rats PPRC/INDIA 37
- 40. Camellia sinensis One of the most commonly consumed beverages in the world with no side-effects Sufficient experimental proof on the effect of Green teas anti-inflammatory and chondro- protective properties at molecular level PPRC/INDIA 39
- 42. Humulus lupulus It contains 32 constituents that have antiinflammatory activities 10 out of them may act as sedative It is popular remedy for rheumatism PPRC/INDIA 41
- 44. Cinnamomum camphora When applied on the affected area camphor may redden the skin and produce a warm sensation When rubbed into painful, stiff joints, ligaments and muscles, it provides soothing camphor-ice relief PPRC/INDIA 43
- 46. Piper nigrum As an external application, it dilates the superficial vessels and acts as a counter-irritant It is used as an analgesic liniment for myalgia and rheumatic pains PPRC/INDIA 45
- 48. Glycyrrhiza glabra It acts on the body without any harmful side-effects It has significant anti-inflammatory and anti-allergy activity It has been historically in the treatment of inflammation, allergy and asthma PPRC/INDIA 47
- 49. Mustard plaster Brassica alba, Brassica juncea PPRC/INDIA 48
- 50. Brassica alba, Brassica juncea Popular counter-irritant treatment for arthritis Active principle allyl-isothiocyanate Crush the seeds in grinder, moisten the mixture with vinegar and sprinkle the flour. Spread mixture on cloth and place it on skin for > 20 mins. After removal, wash the affected area PPRC/INDIA 49
- 52. Ananas comosus Active principle Bromelain helps prevent inflammation Athletic trainers recommend pineapple for athletes to prevent and treat sports injury Bromelain help the body to get rid of immune antigen complex compounds that are implicated in arthritic conditions PPRC/INDIA 51
- 54. Rosmarinus officinalis The leaves of this plant contain carnosal, oleanolic acid rosmarinic acid and ursdic acid which acts as an anti-inflammatory activity PPRC/INDIA 53
- 56. Capsicum sp. It interferes with pain perception It contains capsaicin salicylates and others These help to relieve arthritis PPRC/INDIA 55
- 58. Sesamum indicum Chinese folk medicine to eat seeds 遜 ounce of the seeds contain 4 gm of essential fatty acids, 175 mg of calcium, 64 mg of magnesium, 0.73 mg of copper Increased copper intake may be important during arthritis attacks A rind 遜 ounce of seeds & sprinkle on food PPRC/INDIA 57
- 60. Urtica dioica Official remedy for rheumatism in Germany Most important herb to consider for treating early onset arthritis Contains anti-inflammatory component similar to that of steroid drugs Dose: 1 tablespoon juice thrice a day, freeze the juice if needed PPRC/INDIA 59
- 61. Thunder god vine Tripterygium wilfordii Hook f. PPRC/INDIA 60
- 62. Tripterygium wilfordii Hook f. It is a perennial vine-like plant that grows in Southern China and Taiwan Root extract is for treatment of various autoimmune and inflammatory diseases including RA PPRC/INDIA 61
- 64. Curcuma longa Curcumin, the yellow pigment of Turmeric has significant anti-inflammatory action Curcumin effective as cortisone in inflammation Dosage: 400-600 mg thrice a day Non-toxic dietary pigment quite useful in arthritis It is effective in liver infections PPRC/INDIA 63
- 66. Wild cucumber bark Best plant for treating rheumatism and arthritis It is to be taken in drinking alcohol or tea PPRC/INDIA 65
- 68. Dioscorea villosa Contains Diosgenin a steroid constituent with anti-inflammatory properties Wild yam tea popular folk remedy for muscular rheumatism Dosage: 1 ounce of wild yam root + 1 ginger root = fill jar with boiling water mixture at room temp. Drink 2 3 cups / day PPRC/INDIA 67
- 70. Salix spp. Active principle: Salicin Pain relieving and anti-inflammatory properties PPRC/INDIA 69
- 72. Gaultheria procumbens Chief active principle: Methylsalicylate Dried herb is used PPRC/INDIA 71
- 74. Yucca filamentosa To reduce arthritic pain Saponin extract of Yucca showed positive therapeutic effect It decreases bacterial endotoxin absorption thus reducing inhibition of cartilage synthesis PPRC/INDIA 73
- 75. Thank you !!