This document provides guidelines for emergency response to an outbreak of African swine fever (ASF) in South Korea. It outlines four stages of response based on the situation (concern, caution, serious, stabilization and termination), and describes in detail the procedures for each stage. This includes actions for farmers/workers if sick pigs are found, sample collection and testing, quarantine measures, depopulation of infected pigs, carcass disposal, disinfection, epidemiological investigation and more. The guidelines aim to effectively control and eliminate ASF if detected in South Korea.