This document provides an overview of basic radiation physics concepts including atomic and nuclear structure. It describes Rutherford's model of the atom based on Geiger-Marsden experiments, Bohr's model of the hydrogen atom, and multi-electron atomic structure. Nuclear structure is also summarized, including nuclear reactions, binding energy, and radioisotopes. Radiation is classified as ionizing or non-ionizing, and ionization is defined as the process by which a neutral atom acquires a positive or negative charge.
1. Atoms are the basic building blocks of matter and consist of a small, dense nucleus surrounded by electrons.
2. Rutherford's gold foil experiment in 1911 showed that the atom has a small, dense nucleus containing positively charged protons and uncharged neutrons.
3. Niels Bohr proposed his model of the atom in 1913 where electrons orbit the nucleus in fixed shells at specific energy levels, explaining atomic spectra. However, it did not explain more complex atomic structures.
1. Atoms are the basic building blocks of matter and consist of a small, dense nucleus surrounded by electrons.
2. Rutherford's gold foil experiment in 1911 showed that the atom has a small, dense nucleus containing positively charged protons and uncharged neutrons.
3. Niels Bohr proposed his model of the atom in 1913 in which electrons orbit the nucleus in fixed shells at specific energy levels, explaining atomic spectra.
1. Atoms are the basic building blocks of matter and consist of a small, dense nucleus surrounded by electrons.
2. Rutherford's gold foil experiment in 1911 showed that the atom has a small, dense nucleus containing positively charged protons and uncharged neutrons.
3. Niels Bohr proposed his model of the atom in 1913 where electrons orbit the nucleus in fixed shells at specific energy levels, explaining atomic spectra. However, it did not explain more complex atomic structures.
Lecture 1 medical Chemistry.pptxxfjxfjfjcfSriRam071
油
This document provides an overview of the topics covered in the first lecture of a Medical Chemistry course. The lecture introduced the electronic structure of atoms, including the dual nature of electrons and quantum mechanical descriptions of hydrogen atoms. It also covered quantum numbers, atomic orbitals, electron configuration, and shielding effects in multi-electron atoms. The accompanying seminar discussed principal, angular momentum, magnetic, and electron spin quantum numbers as well as s, p, d, and f orbitals and their energies.
PPT Fisika pada radioterapi dari berbagai sumber2Din3D
油
There are four fundamental forces in nature: strong, electromagnetic, weak, and gravitational. Radiation is classified as either ionizing or non-ionizing. Ionizing photon radiation includes characteristic x-rays, bremsstrahlung, gamma rays, and annihilation radiation. There are two classes of fundamental particles: quarks which experience strong interactions, and leptons which do not interact strongly. Radioactive decay occurs through several modes including alpha decay, beta decay (beta minus and beta plus), electron capture, and gamma decay.
This document provides an overview of the structure of an atom. It discusses that atoms are the building blocks of matter and are made up of protons, neutrons, and electrons. It describes the key parts of an atom - the nucleus which contains protons and neutrons at its center, and electrons that orbit the nucleus. The document outlines Rutherford's atomic model which established that the atom has a small, dense nucleus and Bohr's model which depicted electrons orbiting the nucleus in fixed shells like planets around the sun.
1) The document discusses the structure of atoms and nuclei. It summarizes several historic atomic models including Thomson's plum pudding model, Rutherford's nuclear model, and Bohr's early quantum model of the hydrogen atom.
2) Key aspects of atomic nuclei are described, including their composition of protons and neutrons. The properties of isotopes, isobars, and isotones are defined.
3) Nuclear forces, binding energy, and radioactive decay processes such as alpha decay and beta decay are explained. Alpha decay results in the emission of an alpha particle (helium nucleus) while beta decay changes a neutron to a proton or vice versa.
This document discusses the structure of the atom. It begins by describing Bohr's model of the atom and its limitations. It then introduces shells and subshells, as well as quantum numbers and the shapes of atomic orbitals. Rules for filling electrons into orbitals, such as the Aufbau principle and Pauli exclusion principle, are also covered. The document discusses atomic spectra, photoelectric effect, and the dual wave-particle nature of light and matter. It provides an overview of concepts like de Broglie wavelength, Heisenberg uncertainty principle, and atomic electron configuration.
Structure Of Atom- Science PresentationAkshunChauhan
油
The document summarizes several historical models of the atom:
1. J.J. Thomson's "plum pudding" model which depicted the atom as a positively charged sphere with electrons embedded within it.
2. Ernest Rutherford's gold foil experiment led him to propose the nuclear model with electrons orbiting a small, dense nucleus.
3. Niels Bohr built on this model by incorporating quantum theory to explain electrons occupying discrete energy levels as they orbit the nucleus.
4. Finally, Erwin Schrodinger developed the probabilistic "cloud" model where an electron's location is expressed as a probability distribution or cloud rather than a definite orbit.
The document provides an overview of atomic structure and the periodic table. It discusses how atoms are mostly empty space and their origins in stars. Atoms are made up of protons, neutrons, and electrons. Isotopes have the same number of protons but different neutrons. The periodic table organizes the elements based on their atomic structure. Electrons can only occupy certain energy levels, explaining the emission of light in distinct frequencies.
The document discusses the historical development of the quantum mechanical model of the atom. It describes the key contributions of Niels Bohr, Werner Heisenberg, and Erwin Schr旦dinger in developing the modern atomic model. Additionally, it explains the concept of atomic orbitals, electron configurations, and the rules that govern how electrons fill different energy levels and subshells in an atom.
Module01 nuclear physics and reactor theorysirwaltz73
油
This document provides an overview of a basic professional training course on nuclear physics and reactor theory. It covers topics like atomic structure, the structure of the atom including electrons and the nucleus, isotopes, radioactive decay, and nuclear reactions. The document is divided into several modules, with learning objectives provided for each section. It includes diagrams and examples to illustrate key concepts in nuclear physics.
The document discusses the structure of the atom. It describes how atoms are composed of a nucleus containing protons and neutrons, surrounded by electrons. The nucleus is very small compared to the size of the atom. Electrons orbit the nucleus in specific energy levels. The distribution and number of electrons determines an element's properties. Nuclear stability depends on the ratio of protons to neutrons. Binding energy holds the nucleus together. Various subatomic particles like protons, neutrons and electrons have distinct properties like mass and charge. Nuclear forces interact within the nucleus. Particle radiation involves the emission and propagation of energy by particles with mass and momentum.
The document discusses the history of atomic structure theories including Dalton's, Thomson's, Rutherford's, Bohr's, and the quantum mechanical model. Dalton proposed that atoms are indivisible and compounds form by combination of atoms. Rutherford's gold foil experiment showed that the positive charge and mass of an atom are concentrated in a small nucleus. Bohr incorporated Planck's quantum theory, proposing electrons orbit in discrete energy levels. Later, the quantum mechanical model treated electrons as waves based on de Broglie's idea and Schrodinger's wave equation.
The document discusses atomic models and nuclear physics. It provides information on:
1) Early atomic models including Dalton's billiard ball model, Thomson's plum pudding model, Rutherford's nuclear model, and Bohr's planetary model.
2) Experiments that led to discoveries about the structure of the atom including Thomson's cathode ray tube experiment, Rutherford's gold foil experiment, and Bohr's model of electron orbits.
3) Components of the nucleus including protons, neutrons, and isotopes.
4) Types of radiation including alpha, beta, gamma particles and their properties such as mass, charge, penetration and ionization.
5) Experiments that helped discover radiation and nuclear decay processes.
This document discusses Rutherford's atomic model and Bohr's model of the atom. It provides details of Rutherford's alpha particle scattering experiment which showed that atoms have a small, dense nucleus. This led Rutherford to propose a planetary model of the atom with electrons orbiting the nucleus. The document then discusses limitations of Rutherford's model and how Bohr proposed quantized electron orbits to explain atomic stability. It provides Bohr's key postulates and formulas for the hydrogen atom spectrum and energy levels.
This document discusses the development of atomic theory from ancient Greek philosophers to the modern quantum mechanical model. Key contributors and discoveries include Dalton formulating the first atomic theory, Thomson discovering the electron, Rutherford deducing the nuclear atom from alpha particle scattering experiments, and Bohr, de Broglie, Schrodinger, and others developing quantum mechanics to explain atomic structure and spectra. The modern atomic model consists of electrons in quantized energy levels around an atomic nucleus composed of protons and neutrons, which is summarized by the periodic table and determines chemical properties.
The document provides an overview of basic nuclear physics concepts including atomic structure, isotopes, and nuclear stability. It defines the key subatomic particles that make up atoms - protons, neutrons, and electrons. The nucleus is made up of protons and neutrons, while electrons orbit the nucleus. The number of protons determines the element, while isotopes of an element have different numbers of neutrons. For nuclei to be stable there needs to be a roughly 1:1.5 ratio of protons to neutrons, following the "line of stability". Unstable nuclei are radioactive and decay over time to reach stability.
The document discusses atomic structure and bonding. It describes the structure of atoms including protons, neutrons, and electrons. It explains how atomic number determines the element and how isotopes have the same number of protons but different neutrons. Electron configuration and quantum numbers are also summarized. The three main types of bonds - ionic, covalent, and metallic - are introduced along with how they influence material properties.
Flow chart - Matter's classification
Dalton's atomic theory
Discovery of electrons
Discovery of protons
Thomson's model of atom
Discovery of nucleus
Rutherford's model of atom
Stability of atom
Bohr's model of atom
Discovery of neutron
Sub atomic particles
Modern atomic model
Atomic number & Mass number
Isotopes
Electronic configuration
periodic table
radicals
valency
This document discusses the principles of physics of diagnostic radiology. It describes the structure of atoms including the nucleus containing protons and neutrons, and electrons orbiting in shells. Electrons have binding energies that increase with atomic number and decrease with increasing shell number. Ionization occurs when energy is applied to eject an electron from its shell, creating a vacancy. Excited atoms undergo rearrangement as electrons transition between shells to fill vacancies, and may emit electromagnetic radiation in the process.
The Fundamentals of Chemistry is an introduction to the Periodic Table, stoichiometry, chemical states, chemical equilibria, acid & base, oxidation & reduction reactions, chemical kinetics, inorganic nomenclature, and chemical bonding.
The document discusses the historical development of atomic models from ancient Indian and Greek philosophers' idea of indivisible particles to modern atomic theory. It summarizes Thomson, Rutherford, and Bohr's experimental findings and proposed atomic models. Key points include Rutherford discovering the nucleus through gold foil experiments, Bohr incorporating allowed orbits to explain atomic stability, and the rules for electron configuration in shells. The document also defines related atomic concepts like isotopes, isobars, and mass number.
Electrons are important because their arrangement in atomic orbitals determines an element's properties and reactions. Electrons exhibit both wave-like and particle-like behavior. According to quantum theory, electrons occupy specific atomic orbitals and energy levels. Their configuration is defined by rules like the Aufbau principle and Pauli exclusion principle. Valence electrons in the outermost shell determine an element's chemical behavior.
The document provides an overview of the history of radiation and basic concepts related to radiation. It discusses how radiation was discovered in the late 19th century by scientists like Roentgen, Becquerel, and Curies. It then describes the atomic models developed by Thomson, Rutherford and Bohr to explain the structure of atoms and different types of radiation. Finally, it discusses different types of radiation, dose quantities measured by dosimeters, and commonly used personal dosimeters like TLD badges and film badges.
This document provides an introduction to nuclear physics and radioactivity. It discusses:
1) The discovery of radioactivity and the nucleus. Rutherford's scattering experiment in 1911 revealed the existence of the nucleus as the source of radioactivity.
2) The structure of the nucleus, including its composition of protons and neutrons (nucleons), atomic number, mass number, isotopes, and typical size.
3) Nuclear stability and binding energy. The strong nuclear force holds nuclei together, and nuclei with intermediate mass numbers have the highest binding energy per nucleon. Only certain combinations of protons and neutrons produce stable nuclei.
1) Atoms are the basic building blocks of matter and consist of a nucleus surrounded by electrons. The nucleus contains protons and neutrons, while electrons orbit around the nucleus.
2) Rutherford's gold foil experiment provided evidence that atoms have a small, dense nucleus and that most of an atom's mass and positive charge is concentrated in the nucleus.
3) Bohr's model improved upon earlier models by proposing that electrons orbit in fixed shells and energy levels around the nucleus, explaining the stability of atoms and emission of photons during changes in electron energy levels.
An X-ray generator is a crucial device used in medical imaging, industry, and research to produce X-rays. It operates by accelerating electrons toward a metal target, generating X-ray radiation. Key components include the X-ray tube, transformer assembly, rectifier system, and high-tension circuits. Various types, such as single-phase, three-phase, constant potential, and high-frequency generators, offer different efficiency levels. High-frequency generators are the most advanced, providing stable, high-quality imaging with minimal radiation exposure. X-ray generators play a vital role in diagnostics, security screening, and industrial testing while requiring strict radiation safety measures.
Structure Of Atom- Science PresentationAkshunChauhan
油
The document summarizes several historical models of the atom:
1. J.J. Thomson's "plum pudding" model which depicted the atom as a positively charged sphere with electrons embedded within it.
2. Ernest Rutherford's gold foil experiment led him to propose the nuclear model with electrons orbiting a small, dense nucleus.
3. Niels Bohr built on this model by incorporating quantum theory to explain electrons occupying discrete energy levels as they orbit the nucleus.
4. Finally, Erwin Schrodinger developed the probabilistic "cloud" model where an electron's location is expressed as a probability distribution or cloud rather than a definite orbit.
The document provides an overview of atomic structure and the periodic table. It discusses how atoms are mostly empty space and their origins in stars. Atoms are made up of protons, neutrons, and electrons. Isotopes have the same number of protons but different neutrons. The periodic table organizes the elements based on their atomic structure. Electrons can only occupy certain energy levels, explaining the emission of light in distinct frequencies.
The document discusses the historical development of the quantum mechanical model of the atom. It describes the key contributions of Niels Bohr, Werner Heisenberg, and Erwin Schr旦dinger in developing the modern atomic model. Additionally, it explains the concept of atomic orbitals, electron configurations, and the rules that govern how electrons fill different energy levels and subshells in an atom.
Module01 nuclear physics and reactor theorysirwaltz73
油
This document provides an overview of a basic professional training course on nuclear physics and reactor theory. It covers topics like atomic structure, the structure of the atom including electrons and the nucleus, isotopes, radioactive decay, and nuclear reactions. The document is divided into several modules, with learning objectives provided for each section. It includes diagrams and examples to illustrate key concepts in nuclear physics.
The document discusses the structure of the atom. It describes how atoms are composed of a nucleus containing protons and neutrons, surrounded by electrons. The nucleus is very small compared to the size of the atom. Electrons orbit the nucleus in specific energy levels. The distribution and number of electrons determines an element's properties. Nuclear stability depends on the ratio of protons to neutrons. Binding energy holds the nucleus together. Various subatomic particles like protons, neutrons and electrons have distinct properties like mass and charge. Nuclear forces interact within the nucleus. Particle radiation involves the emission and propagation of energy by particles with mass and momentum.
The document discusses the history of atomic structure theories including Dalton's, Thomson's, Rutherford's, Bohr's, and the quantum mechanical model. Dalton proposed that atoms are indivisible and compounds form by combination of atoms. Rutherford's gold foil experiment showed that the positive charge and mass of an atom are concentrated in a small nucleus. Bohr incorporated Planck's quantum theory, proposing electrons orbit in discrete energy levels. Later, the quantum mechanical model treated electrons as waves based on de Broglie's idea and Schrodinger's wave equation.
The document discusses atomic models and nuclear physics. It provides information on:
1) Early atomic models including Dalton's billiard ball model, Thomson's plum pudding model, Rutherford's nuclear model, and Bohr's planetary model.
2) Experiments that led to discoveries about the structure of the atom including Thomson's cathode ray tube experiment, Rutherford's gold foil experiment, and Bohr's model of electron orbits.
3) Components of the nucleus including protons, neutrons, and isotopes.
4) Types of radiation including alpha, beta, gamma particles and their properties such as mass, charge, penetration and ionization.
5) Experiments that helped discover radiation and nuclear decay processes.
This document discusses Rutherford's atomic model and Bohr's model of the atom. It provides details of Rutherford's alpha particle scattering experiment which showed that atoms have a small, dense nucleus. This led Rutherford to propose a planetary model of the atom with electrons orbiting the nucleus. The document then discusses limitations of Rutherford's model and how Bohr proposed quantized electron orbits to explain atomic stability. It provides Bohr's key postulates and formulas for the hydrogen atom spectrum and energy levels.
This document discusses the development of atomic theory from ancient Greek philosophers to the modern quantum mechanical model. Key contributors and discoveries include Dalton formulating the first atomic theory, Thomson discovering the electron, Rutherford deducing the nuclear atom from alpha particle scattering experiments, and Bohr, de Broglie, Schrodinger, and others developing quantum mechanics to explain atomic structure and spectra. The modern atomic model consists of electrons in quantized energy levels around an atomic nucleus composed of protons and neutrons, which is summarized by the periodic table and determines chemical properties.
The document provides an overview of basic nuclear physics concepts including atomic structure, isotopes, and nuclear stability. It defines the key subatomic particles that make up atoms - protons, neutrons, and electrons. The nucleus is made up of protons and neutrons, while electrons orbit the nucleus. The number of protons determines the element, while isotopes of an element have different numbers of neutrons. For nuclei to be stable there needs to be a roughly 1:1.5 ratio of protons to neutrons, following the "line of stability". Unstable nuclei are radioactive and decay over time to reach stability.
The document discusses atomic structure and bonding. It describes the structure of atoms including protons, neutrons, and electrons. It explains how atomic number determines the element and how isotopes have the same number of protons but different neutrons. Electron configuration and quantum numbers are also summarized. The three main types of bonds - ionic, covalent, and metallic - are introduced along with how they influence material properties.
Flow chart - Matter's classification
Dalton's atomic theory
Discovery of electrons
Discovery of protons
Thomson's model of atom
Discovery of nucleus
Rutherford's model of atom
Stability of atom
Bohr's model of atom
Discovery of neutron
Sub atomic particles
Modern atomic model
Atomic number & Mass number
Isotopes
Electronic configuration
periodic table
radicals
valency
This document discusses the principles of physics of diagnostic radiology. It describes the structure of atoms including the nucleus containing protons and neutrons, and electrons orbiting in shells. Electrons have binding energies that increase with atomic number and decrease with increasing shell number. Ionization occurs when energy is applied to eject an electron from its shell, creating a vacancy. Excited atoms undergo rearrangement as electrons transition between shells to fill vacancies, and may emit electromagnetic radiation in the process.
The Fundamentals of Chemistry is an introduction to the Periodic Table, stoichiometry, chemical states, chemical equilibria, acid & base, oxidation & reduction reactions, chemical kinetics, inorganic nomenclature, and chemical bonding.
The document discusses the historical development of atomic models from ancient Indian and Greek philosophers' idea of indivisible particles to modern atomic theory. It summarizes Thomson, Rutherford, and Bohr's experimental findings and proposed atomic models. Key points include Rutherford discovering the nucleus through gold foil experiments, Bohr incorporating allowed orbits to explain atomic stability, and the rules for electron configuration in shells. The document also defines related atomic concepts like isotopes, isobars, and mass number.
Electrons are important because their arrangement in atomic orbitals determines an element's properties and reactions. Electrons exhibit both wave-like and particle-like behavior. According to quantum theory, electrons occupy specific atomic orbitals and energy levels. Their configuration is defined by rules like the Aufbau principle and Pauli exclusion principle. Valence electrons in the outermost shell determine an element's chemical behavior.
The document provides an overview of the history of radiation and basic concepts related to radiation. It discusses how radiation was discovered in the late 19th century by scientists like Roentgen, Becquerel, and Curies. It then describes the atomic models developed by Thomson, Rutherford and Bohr to explain the structure of atoms and different types of radiation. Finally, it discusses different types of radiation, dose quantities measured by dosimeters, and commonly used personal dosimeters like TLD badges and film badges.
This document provides an introduction to nuclear physics and radioactivity. It discusses:
1) The discovery of radioactivity and the nucleus. Rutherford's scattering experiment in 1911 revealed the existence of the nucleus as the source of radioactivity.
2) The structure of the nucleus, including its composition of protons and neutrons (nucleons), atomic number, mass number, isotopes, and typical size.
3) Nuclear stability and binding energy. The strong nuclear force holds nuclei together, and nuclei with intermediate mass numbers have the highest binding energy per nucleon. Only certain combinations of protons and neutrons produce stable nuclei.
1) Atoms are the basic building blocks of matter and consist of a nucleus surrounded by electrons. The nucleus contains protons and neutrons, while electrons orbit around the nucleus.
2) Rutherford's gold foil experiment provided evidence that atoms have a small, dense nucleus and that most of an atom's mass and positive charge is concentrated in the nucleus.
3) Bohr's model improved upon earlier models by proposing that electrons orbit in fixed shells and energy levels around the nucleus, explaining the stability of atoms and emission of photons during changes in electron energy levels.
An X-ray generator is a crucial device used in medical imaging, industry, and research to produce X-rays. It operates by accelerating electrons toward a metal target, generating X-ray radiation. Key components include the X-ray tube, transformer assembly, rectifier system, and high-tension circuits. Various types, such as single-phase, three-phase, constant potential, and high-frequency generators, offer different efficiency levels. High-frequency generators are the most advanced, providing stable, high-quality imaging with minimal radiation exposure. X-ray generators play a vital role in diagnostics, security screening, and industrial testing while requiring strict radiation safety measures.
Op-eds and commentaries 101: U-M IHPI Elevating Impact seriesKara Gavin
油
A slide set about writing opinion and commentary pieces, created for the University of Michigan Institute for Healthcare Policy and Innovation in Jan. 2025
BIOMECHANICS OF THE MOVEMENT OF THE SHOULDER COMPLEX.pptxdrnidhimnd
油
The shoulder complex acts as in coordinated fashion to provide the smoothest and greatest range of motion possible of the upper limb.
Combined motion of GH and ST joint of shoulder complex helps in:
Distribution of motion between other two joints.
Maintenance of glenoid fossa in optimal position.
Maintenance of good length tension
Although some amount of glenohumeral motion may occur while the other shoulder articulations remain stabilized, movement of the humerus more commonly involves some movement at all three shoulder joints.
1. Explain the physiological control of glomerular filtration and renal blood flow
2. Describe the humoral and autoregulatory feedback mechanisms that mediate the autoregulation of renal plasma flow and glomerular filtration rate
Best Sampling Practices Webinar USP <797> Compliance & Environmental Monito...NuAire
油
Best Sampling Practices Webinar USP <797> Compliance & Environmental Monitoring
Are your cleanroom sampling practices USP <797> compliant? This webinar, hosted by Pharmacy Purchasing & Products (PP&P Magazine) and sponsored by NuAire, features microbiology expert Abby Roth discussing best practices for surface & air sampling, data analysis, and compliance.
Key Topics Covered:
鏝 Viable air & surface sampling best practices
鏝 USP <797> requirements & compliance strategies
鏝 How to analyze & trend viable sample data
鏝 Improving environmental monitoring in cleanrooms
・ Watch Now: https://www.nuaire.com/resources/best-sampling-practices-cleanroom-usp-797
Stay informedfollow Abby Roth on LinkedIn for more cleanroom insights!
Here discussing various cases of Obstructive jaundice namely Choledocholithiassis, Biliary atresia, Carcinoma Pancreas, Periampullary Carcinoma and Cholangiocarcinoma.
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...Ganapathi Vankudoth
油
A complete information of Inflammation, it includes types of Inflammation, purpose of Inflammation, pathogenesis of acute inflammation, chemical mediators in inflammation, types of chronic inflammation, wound healing and Inflammation in skin repair, phases of wound healing, factors influencing wound healing and types of wound healing.
The course covers the steps undertaken from tissue collection, reception, fixation,
sectioning, tissue processing and staining. It covers all the general and special
techniques in histo/cytology laboratory. This course will provide the student with the
basic knowledge of the theory and practical aspect in the diagnosis of tumour cells
and non-malignant conditions in body tissues and for cytology focusing on
gynaecological and non-gynaecological samples.
Asthma: Causes, Types, Symptoms & Management A Comprehensive OverviewDr Aman Suresh Tharayil
油
This presentation provides a detailed yet concise overview of Asthma, a chronic inflammatory disease of the airways. It covers the definition, etiology (causes), different types, signs & symptoms, and common triggers of asthma. The content highlights both allergic (extrinsic) and non-allergic (intrinsic) asthma, along with specific forms like exercise-induced, occupational, drug-induced, and nocturnal asthma.
Whether you are a healthcare professional, student, or someone looking to understand asthma better, this presentation offers valuable insights into the condition and its management.
ECZEMA 3rd year notes with images .pptxAyesha Fatima
油
If its not Itch Its not Eczema
Eczema is a group of medical conditions which causes inflammation and irritation to skin.
It is also called as Dermatitis
Eczema is an itchy consisting of ill defined erythremotous patches. The skin surface is usually scaly and As time progress, constant scratching leads to thickened lichenified skin.
Several classifications of eczemas are available based on Etiology, Pattern and chronicity.
According to aetiology Eczema are classified as:
Endogenous eczema: Where constitutional factors predispose the patient to developing an eczema.
Family history (maternal h/o eczema) is often present
Strong genetic predisposition (Filaggrin gene mutations are often present).
Filaggrin is responsible for maintaining moisture in skin (hence all AD patients have dry skin.
Immunilogical factor-Th-2 disease, Type I hypersensitivity (hence serum IgE high)
e.g., Seborrheic dermatitis, Statis dermatitis, Nummular dermatitis, Dyshidrotic Eczema
Exogenous eczema: Where external stimuli trigger development of eczema,
e.g., Irritant dermatitis, Allergic Dermatitis, Neurodermatitis,
Combined eczema: When a combination of constitutional factors and extrinsic triggers are responsible for the development of eczema
e.g., Atopic dermatitis
Extremes of Temperature
Irritants : Soaps, Detergents, Shower gels, Bubble baths and water
Stress
Infection either bacterial or viral,
Bacterial infections caused by Staphylococcus aureus and Streptococcus species.
Viral infections such as Herpes Simplex, Molluscum Contagiosum
Contact allergens
Inhaled allergens
Airborne allergens
Allergens include
Metals eg. Nickle, Cobalt
Neomycin, Topical ointment
Fragrance ingredients such as Balsam of Peru
Rubber compounds
Hair dyes for example p-Phenylediamine
Plants eg. Poison ivy .
Atopic Dermatitis : AD is a chronic, pruritic inflammatory skin disease characterized by itchy inflamed skin.
Allergic Dermatitis: A red itchy weepy reaction where the skin has come in contact with a substance That immune system recognizes as foreign substances.
Ex: Poison envy, Preservatives from creams and lotions.
Contact Irritant Dermatitis: A Localized reaction that include redness, itching and burning where the skin has come In contact with an allergen or with irritant such as acid, cleaning agent or chemical.
Dyshidrotic Eczema: Irritation of skin on the palms and soles by
clear deep blisters that itch and burn.
Clinical Features; Acute Eczema:- Acute eczema is characterized by an erythematous and edematous plaque, which is ill-defined and is surmounted by papules, vesicles, pustules and exudate that dries to form crusts. A subsiding eczematous plaque may be covered with scales.
Chronic Eczema:- Chronic eczema is characterized by lichenification, which is a triad of hyperpigmentation, thickening markings. The lesions are less exudative and more scaly. Flexural lesions may develop fissures.
Pruritus
Characteristic Rash
Chronic or repeatedly occurring symptoms.
7. The periodic table of elements lists the elements in ascending order of atomic number
9. 1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.1 Basic definitions for atomic structure
The constituent particles forming an atom are:
Proton
Neutron
Electron
Protons and neutrons are known as nucleons and form the
nucleus.
Atomic number Z
Number of protons and number of electrons in an atom.
10. 1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.1 Basic definitions for atomic structure
Atomic mass number A
Number of nucleons (Z+N) in an atom,
where
Z is the number of protons (atomic number) in an atom
N is the number of neutrons in an atom.
11. ATOMIC AND NUCLEAR STRUCTURE
Basic definitions for atomic structure
In nuclear physics the convention is to designate a
nucleus X as
where
A is the atomic mass number
Z is the atomic number
For example:
Cobalt-60 nucleus with Z = 27 protons and A = 33 neutrons is
identified as .
Radium-226 nucleus with 88 protons and 138 neutrons is
identified as .
Z
A
X
88
226
Ra
27
60
Co
12. 1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.2 Rutherfords model of the atom
Rutherfords atomic model is based on results of the
Geiger-Marsden experiment of 1909 with 5.5 MeV
alpha particles scattered on thin gold foils with a
thickness of the order of 10-6 m.
13. Review of Radiation Oncology Physics: A
Handbook for Teachers and Students -
1.2.2 際際滷 2
1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.2 Rutherfords model of the atom
At the time of the Geiger-Marsden experiment Thomson
atomic model was the prevailing atomic model.
The model was based on an
assumption that the positive
and the negative (electron)
charges of the atom were
distributed uniformly over the
atomic volume
(plum-pudding model).
14. Review of Radiation Oncology Physics: A
Handbook for Teachers and Students -
1.2.2 際際滷 4
1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.2 Rutherfords model of the atom
Ernest Rutherford concluded that the peculiar results of
the Geiger-Marsden experiment did not support the
Thomsons atomic model and proposed the currently
accepted atomic model in which:
Mass and positive charge of the
atom are concentrated in the
nucleus the size of which is
of the order of 10-15 m.
Negatively charged electrons
revolve about the nucleus in
a spherical cloud on the periphery
of the Rutherford atom with a
radius of the order of 10-10 m.
15. Review of Radiation Oncology Physics: A
Handbook for Teachers and Students -
1.2.2 際際滷 5
1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.2 Rutherfords model of the atom
Based on his model and four additional assumptions,
Rutherford derived the kinematics for the scattering
of alpha particles on gold nuclei using basic principles
of classical mechanics.
The four assumptions are related to:
Mass of the gold nucleus.
Scattering of alpha particles.
Penetration of the nucleus.
Kinetic energy of the alpha particles.
16. Review of Radiation Oncology Physics: A
Handbook for Teachers and Students -
1.2.2 際際滷 6
1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.2 Rutherfords model of the atom
The four assumptions are:
Mass of the gold nucleus >> mass of the alpha particle.
Scattering of alpha particles on atomic electrons is
negligible.
Alpha particle does not penetrate the nucleus, i.e., there
are no nuclear reactions occurring.
Alpha particles with kinetic energies of the order of a few
MeV are non-relativistic and the simple classical
relationship for the kinetic energy EK of the alpha particle is
valid: ¥
2
K
2
m
E
17. Review of Radiation Oncology Physics: A
Handbook for Teachers and Students -
1.2.3 際際滷 1
1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.3 Bohrs model of the hydrogen atom
Niels Bohr in 1913 combined Rutherfords concept of
the nuclear atom with Plancks idea of the quantized
nature of the radiation process and developed an
atomic model that successfully deals with one-
electron structures, such as the hydrogen atom, singly
ionized helium, etc.
M nucleus with mass M
me electron with mass me
rn radius of electron orbit
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.3 Bohrs model of the hydrogen atom
Bohrs atomic model is based on four postulates:
Postulate 1: Electrons revolve about the Rutherford nucleus
in well-defined, allowed orbits (planetary-like motion).
Postulate 2: While in orbit, the electron does not lose any
energy despite being constantly accelerated (no energy
loss while electron is in allowed orbit).
Postulate 3: The angular momentum of the electron in
an allowed orbit is quantized (quantization of angular
momentum).
Postulate 4: An atom emits radiation only when an electron
makes a transition from one orbit to another (energy
emission during orbital transitions).
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.3 Bohrs model of the hydrogen atom
Energy levels En of
orbital electron shells
in a one-electron
Bohr atom are:
ER = Rydberg energy
En
ER
Z
n
2
13.6 eV
Z
n
2
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.4 Multi-electron atom
Energy level diagram for
multi-electron atom (lead)
Shell (orbit) designations:
n = 1 K shell (2 electrons)
n = 2 L shell (8 electrons)
n = 3 M shell (18 electrons)
n = 4 N shell (32 electrons)
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.5 Nuclear structure
Most of the atomic mass is concentrated in the
atomic nucleus consisting of Z protons and A-Z
neutrons where Z is the atomic number and A the
atomic mass number (Rutherford-Bohr atomic
model).
Protons and neutrons are commonly called nucleons
and are bound to the nucleus with the strong force.
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.5 Nuclear structure
In contrast to the electrostatic and gravitational forces
that are inversely proportional to the square of the
distance between two particles, the strong force
between two particles is a very short range force,
active only at distances of the order of a few
femtometers.
Radius r of the nucleus is estimated from: ,
where ro is the nuclear radius constant (1.4 fm).
r ro
A
3
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.5 Nuclear structure
The sum of masses of the individual components of a
nucleus that contains Z protons and (A-Z) neutrons is
larger than the mass of the nucleus M.
This difference in masses is called the mass defect
(deficit) and its energy equivalent is called
the total binding energy EB of the nucleus:
m mc2
EB
Zmp
c2
(A Z)mn
c2
Mc2
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.5 Nuclear structure
The binding energy per nucleon (EB/A) in a nucleus varies
with the number of nucleons A and is of the order of 8
MeV per nucleon.
EB
A
Zmp
c2
(A Z)mn
c2
Mc2
A
Nucleus EB/A (MeV)
1.1
2.8
2.6
7.1
8.8
7.3
2
1H
3
1H
3
1He
4
1He
60
27Co
238
92U
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1.2 ATOMIC AND NUCLEAR STRUCTURE
1.2.6 Nuclear reactions
Nuclear reaction:
Projectile (a) bombards target (A)
which is transformed into nuclei (B) and (b).
The most important physical quantities that are
conserved in a nuclear reaction are:
Charge
Mass number
Linear momentum
Mass-energy
A a B b or A(a,b)B
26. RADIO NUCLIDES
Nuclei having different number of protons, neutrons, or both are
called nuclides.
Unstable nuclides are called Radionuclides ,and atoms with unstable
nuclei are called Radioisotopes.
27. Nuclear Terminology
Nuclides with the same number of protons and different number of
neutrons== Isotopes
Nuclides with the same number of neutrons but different number of
protons== Isotones
Nuclides with the same number of nucleons == Isobars
Identical nuclides with different energy states == Isomers
31. Classification of radiation
Radiation is classified into two main categories:
Non-ionizing radiation (cannot ionize matter).
Ionizing radiation (can ionize matter).
Directly ionizing radiation (charged particles)
electron, proton, alpha particle, heavy ion
Indirectly ionizing radiation (neutral particles)
photon (x ray, gamma ray), neutron
32. The process by which a neutral atom acquires a positive
or negative charge
Ionization
electron is
stripped from
atom
-
-
-
-
The neutral atom
gains a + charge
= an ion
33. Ionization: Removal of electrons
Excitation: Shifting of an electron to a higher energy level
35. Binding Energy
Energy required to remove an electron completely from an
atom
By convention, binding energies are negative with increasing
magnitude for electrons in shells closer to the nucleus
Binding energy of electrons in a particular orbit increases with
the number of protons in the nucleus (i.e., atomic number, Z)