Before & after photos
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This document promotes the dental services available at Om Dental Care and Implant Centre. It provides before and after photos showing the clinic's work with Emax laminates and crowns, tooth colored fillings for broken teeth, space maintainers for missing teeth, porcelain laminates to mask fillings, complete dentures, metal-free restorations, and dental implants. The clinic claims to offer a one stop solution for all dental needs including complex full mouth rehabilitation cases.
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Peptic Ulcer Disease (PUD) and Gastroesophageal Reflux Disease (GERD) are distinct yet overlapping disorders of the gastrointestinal system, marked by significant morbidity worldwide. These conditions illustrate the consequence of a disturbed harmony between offensive gastric secretions and the protective barriers of the mucosa. From ancient remedies to modern-day proton pump inhibitors and eradication therapies, the treatment approaches to these disorders represent a triumph of translational medicine.
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II. Peptic Ulcer Disease (PUD)
Definition and Epidemiology
Peptic ulcers are breaks in the mucosal lining of the stomach or duodenum that penetrate the muscularis mucosa. Gastric ulcers typically occur on the lesser curvature of the stomach, while duodenal ulcers are found in the first part of the duodenum.
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Helicobacter pylori infection Present in ~90% of duodenal and 70% of gastric ulcers.
NSAIDs Inhibit prostaglandin synthesis, compromising mucosal defense.
Smoking Impairs mucosal healing.
Stress (critical illness) Leads to stress ulcers.
Zollinger-Ellison Syndrome Gastrinoma with excess acid secretion.
Corticosteroids, alcohol, and genetic predisposition are other contributors.
Pathophysiology
The balance between aggressive factors (acid, pepsin, H. pylori, NSAIDs) and defensive mechanisms (mucus, bicarbonate, blood flow, prostaglandins) determines mucosal integrity.
H. pylori causes chronic inflammation and epithelial damage. NSAIDs decrease prostaglandins, reducing mucosal blood flow and bicarbonate production.
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III. Clinical Features of Peptic Ulcer
Epigastric pain: Most common symptom; burning or gnawing in nature.
Duodenal ulcers: Pain relieved by food, occurs 23 hours after meals.
Gastric ulcers: Pain worsens with food intake.
Nausea, bloating, early satiety
Complications:
Bleeding: Hematemesis, melena.
Perforation: Sudden severe abdominal pain.
Gastric outlet obstruction
Penetration into adjacent organs (e.g., pancreas)
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IV. Diagnosis of Peptic Ulcer
Endoscopy: Gold standard for diagnosis and biopsy to rule out malignancy.
Rapid urease test, histology, urea breath test, stool antigen for H. pylori.
Serologic testing (less preferred).
Barium study
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The presentation highlights factors contributing to the emergence and resurgence of diseases, including globalization, increased human-animal interaction, urbanization, climate change, deforestation, antimicrobial resistance (AMR), and gaps in immunization. Through relevant case studies and recent outbreaks such as COVID-19, Nipah virus, Zika, Ebola, Monkeypox, Dengue, Tuberculosis, and others, the seminar underscores the importance of disease surveillance, rapid response systems, and the One Health approach.
It also discusses the role of national and international health agencies like WHO, CDC, and Indias IDSP in disease monitoring and control. The presentation is enriched with visuals, stats, and key strategies for prevention and control, making it a valuable educational tool for medical students, community medicine postgraduates, public health professionals, and policy makers.
By the end of this seminar, viewers will gain a deeper understanding of how emerging and re-emerging diseases pose evolving threats and how a proactive, multidisciplinary public health response is essential to safeguard communities globally.
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CMH Multan Institute of Medical Sciences
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鏝 Who Should Attend/View This Lecture?
This lecture is designed to cater to a wide academic and clinical audience:
First and Second-Year MBBS students
Allied health sciences students (Nursing, DPT, MLS, etc.)
Interns and medical residents revising clinical hematology
Medical educators preparing instructional content
Й Lab professionals and technologists refining interpretation skills
Postgraduate students in Physiology or Pathology
Topics Covered in This Lecture 際際滷 Deck:
RBC Count Normal ranges for adults and neonates
Hemoglobin (Hb) Clinical importance in oxygen transport
Packed Cell Volume (PCV) Significance in hematocrit analysis
MCV (Mean Corpuscular Volume) Cell sizing & anemia classification
MCH (Mean Corpuscular Hemoglobin) Hemoglobin mass per RBC
MCHC (Mean Corpuscular Hemoglobin Concentration) Indicator of chromicity
Color Index (CI) Traditional but insightful ratio-based tool
RDW (Red Cell Distribution Width) Variability in cell size and clinical implications
Osmotic Fragility A functional test for membrane integrity and deformability
What Makes This Lecture Unique?
Simple and focused definitions with clinical relevance
Step-by-step calculations using real-world examples
Interpretive insights for differential diagnosis
Color-coded cues and visually intuitive slides
Bonus learning tips for quick recall and exam preparation
Whether you're preparing for a professional exam, clarifying core concepts, or refining your teaching toolsthis 際際滷Share resource serves as an essential visual companion in your academic journey.
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Various modern analytical techniques used in Quantification of Adulterants present in herbal product.
Examples of various drugs causing adulteration in Herbal products.
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