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Prevention of Sudden Cardiac Death With
Implantable Cardioverter-Defibrillators in Children
and Adolescents With Hypertrophic
Cardiomyopathy
Presented By: Jennifer Glen, Mi Hae Kim,
Rosangel Vargas
Overview
 Objectives
 Background
 Methods
 Results
 Conclusion
 Critiques
 Q&A
Objective
 To determine the efficacy of ICDs in
children and adolescents with HCM
Background
 What is HCM?
 HCM is the most
common cause
of SD in children
and young adults
Implantable Cardioverter Defibrillator (ICD)
Types of ICDs
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Abbreviations and Acronyms
HCM - Hypertrophic Cardiomyopathy
ICD - Implantable Cardioverter Defibrillator
LV - Left Ventricle
LVH - Left Ventricular Hypertrophy
SD - Sudden Death
VF - Ventricular Fibrillation
VT - Ventricular Tachycardia
Methods
 Patient Selection
 Defibrillators
 Risk Factor Analysis
Results
 Baseline Characteristics
 ICD interventions /Timing
 Drugs
 Risk Factor Analysis
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Discussion
 History of HCM Studies
 In this study
o Children and Adolescents ( < 20 years )
o Effective 20 % (  90% with No or mild Symptoms)
 Who gets ICD among HCM patients
o Extreme LVH
o Syncope
o Family History
o Hypotensive BP response to exercise
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with  Hypertrophic Cardio Myopathy
Conclusion
 Successful !
 Pros and Cons
Critiques
 Data
 Words
Reference
Maron BJ, Spirito P, Ackerman MJ, Casey SA,Semsarian C, Estes M,
Shannon KM, Ashley EA, Day SM, Pacileo G, Formisano F, Devoto E,
Anastasakis A, Bos JM, Woo A, Autore C, Pass RH, Boriani G, Garberich
RF, Almquist AK, Russell MW, Boni L, Berger S, Maron MS,Link MS.
2013. Prevention of Sudden Cardiac Death With Implantable Cardioverter-
Defilbrillators in Children and Adolescents With Hypertrophic
Cardiomyopathy. Journal of American College of Cardiology (No.14)
[Internet]. [2013 April 09, cited 2015 March 13] Vol. 61. Available from:
http://content.onlinejacc.org/mobile/article.aspx?articleid=1673454
Questions?

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Prevention of Sudden Cardiac Death with Implantable Cardiac Defibrillators in Children and Adolescents with Hypertrophic Cardio Myopathy

  • 1. Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defibrillators in Children and Adolescents With Hypertrophic Cardiomyopathy Presented By: Jennifer Glen, Mi Hae Kim, Rosangel Vargas
  • 2. Overview Objectives Background Methods Results Conclusion Critiques Q&A
  • 3. Objective To determine the efficacy of ICDs in children and adolescents with HCM
  • 4. Background What is HCM? HCM is the most common cause of SD in children and young adults
  • 8. Abbreviations and Acronyms HCM - Hypertrophic Cardiomyopathy ICD - Implantable Cardioverter Defibrillator LV - Left Ventricle LVH - Left Ventricular Hypertrophy SD - Sudden Death VF - Ventricular Fibrillation VT - Ventricular Tachycardia
  • 9. Methods Patient Selection Defibrillators Risk Factor Analysis
  • 10. Results Baseline Characteristics ICD interventions /Timing Drugs Risk Factor Analysis
  • 17. Discussion History of HCM Studies In this study o Children and Adolescents ( < 20 years ) o Effective 20 % ( 90% with No or mild Symptoms) Who gets ICD among HCM patients o Extreme LVH o Syncope o Family History o Hypotensive BP response to exercise
  • 20. Conclusion Successful ! Pros and Cons
  • 22. Reference Maron BJ, Spirito P, Ackerman MJ, Casey SA,Semsarian C, Estes M, Shannon KM, Ashley EA, Day SM, Pacileo G, Formisano F, Devoto E, Anastasakis A, Bos JM, Woo A, Autore C, Pass RH, Boriani G, Garberich RF, Almquist AK, Russell MW, Boni L, Berger S, Maron MS,Link MS. 2013. Prevention of Sudden Cardiac Death With Implantable Cardioverter- Defilbrillators in Children and Adolescents With Hypertrophic Cardiomyopathy. Journal of American College of Cardiology (No.14) [Internet]. [2013 April 09, cited 2015 March 13] Vol. 61. Available from: http://content.onlinejacc.org/mobile/article.aspx?articleid=1673454