Over 300 million families worldwide are affected by inherited hemoglobin diseases but CRISPR gene editing offers a potential cure. The document outlines a treatment strategy using CRISPR to modify the hemoglobin gene in patients, allowing production of functional fetal hemoglobin and a cure. This approach has shown promise in genetically modifying cells to increase fetal hemoglobin levels by 100%, and the goal is to benefit millions through clinical trials and an approved therapy by 2035.
Jenny McDowell from Monash University in Australia wants to include sustainability education in their course offerings going forward. She stated "I AM KEEN TO INCORPORATE SUSTAINABILITY EDUCATION IN OUR COURSES AS WE GO FORWARD." McDowell is looking to add sustainability topics to the university's curriculum.
The document introduces Viewfinder, a new dialogue method and crowdsourced platform to facilitate interdisciplinary work between scientists and help the public better understand science. It provides contact information for the founders and outlines their goals of initially engaging scientists, then policy makers, and ultimately the broader public to help address the challenge that science can feel fragmented and difficult to understand for non-experts.
The document outlines the Hasso Plattner Institute's School of Design Thinking, highlighting its founding, focus on innovation, and diverse student body comprising 120 students across 20 nationalities. It details the course structure, principles of design thinking, and examples of student projects aimed at addressing social challenges. Additionally, it mentions professional tracks for corporate training and collaborations in various fields such as health and logistics.
The document discusses the importance of impact in health and social programs, specifically focusing on the history of maternity and child care clinics in Finland and their success in reducing maternal and infant mortality rates. It highlights the role of health sisters and midwives in providing essential prenatal care, achieving near-total coverage of pregnant women by 2015. Additionally, it mentions the development of a new population projection model informed by ongoing research and collaboration with policymakers in various Asian regions.
The document discusses happiness and how it relates to interaction with others. It argues that happiness is found through interaction rather than by pursuing it alone or viewing it as a possession. The challenge is developing linguistic awareness and concrete tools to change behavior and spread ideas about finding happiness in interaction. The project aims to participate in schools, workplaces and media to provide solutions.
This document outlines the process and activities for a challenge to develop solutions that create impact. It involves defining problems, ideating concepts, testing feasibility, and delivering solutions through converging and diverging phases. Participants are guided to define target users, partners, and scope of impact. The process focuses on understanding needs, benefits, resources, and touchpoints through user research. It aims to develop solutions in collaboration with partners and users to maximize real-world impact.
The document discusses the need for reforming curricula to create a "Generation Green" with a strong environmental focus. It notes that the global population is projected to reach 9 billion by 2050, putting increasing pressure on limited resources like clean drinking water, which over 1.8 billion people currently lack access to. Individual actions alone will not lead to sustainable solutions, so curricula are needed to facilitate a comprehensive understanding of environmental resource management and ensure clean resources for all through scalable, sustainable practices. The document calls readers to join this effort to educate the next "Generation Green" and help address worldwide resource challenges.
The Helsinki Sleep Factory is a virtual sleep society that aims to help adolescents understand and improve their sleep through a combination of chronobiology, motivational psychology, medicine, and problem-based learning approaches. It provides personalized sleep resources and solutions through an intelligent sleep diary, relaxation and mindfulness exercises, and a social community for sharing sleep-related content. The goal is to create accessible and effective interventions for conditions like delayed sleep phase, which can cause learning problems and school absenteeism if not addressed.
Biodiversity is being destroyed through many small incremental changes over time. This loss threatens our well-being and ability to adapt to climate change. To address this, the document proposes developing new mechanisms to neutralize negative impacts on biodiversity and turn losses into gains, such as through biodiversity offsets. Offsets involve compensating for biodiversity loss in one area by improving biodiversity elsewhere. This could create a market-based solution and new business opportunities, implementing the "polluter pays" principle. The proposal aims to incorporate offsets into legislation to balance development with conserving biodiversity in Finland.
This document proposes creating a "Citizen Mindscapes" project to analyze social media data from Suomi24 discussions in order to:
1) Detect early signs of social conflicts and problems in Finland;
2) Work against national divisions and support diversity; and
3) Strengthen skills in social big data analysis for research and business.
The project would involve analyzing the tens of millions of texts on Suomi24, which is used by 80% of Finns, to understand sentiments, consumption styles, hate speech, behaviors, and rhythms of everyday life and the economy.
This document discusses a challenge to connect and empower children in hospitals. It proposes an approach called Play-Learn-Heal that uses co-creation and human-centered design methods to develop social, material and digital solutions. These solutions aim to empower children, reduce stress, connect them to family and learning, and expand support networks during their hospital care and recovery. An interdisciplinary team of children, healthcare professionals, educators, designers and technologists will work together to create and test prototypes to positively impact children, hospitals, research and society.
This document discusses the need for a new approach to communicating information about climate change called "Climate Whirl". It notes that current information is fragmented across disciplines and sources, making it difficult for most people to understand climate change as a whole. Climate Whirl would be a science-based aggregator that combines climate and environmental information with health, social, and consumer insights using games, art, and citizen science to make climate change more understandable and relevant to everyday life. It would be developed by an interdisciplinary team with expertise in areas like environmental education, climate research, and public health.
The document introduces Viewfinder, a new dialogue method and crowdsourced platform to facilitate interdisciplinary work between scientists and help the public better understand science. It provides contact information for the founders and outlines their goals of initially engaging scientists, then policy makers, and ultimately the broader public to help address the challenge that science can feel fragmented and difficult to understand for non-experts.
The document outlines the Hasso Plattner Institute's School of Design Thinking, highlighting its founding, focus on innovation, and diverse student body comprising 120 students across 20 nationalities. It details the course structure, principles of design thinking, and examples of student projects aimed at addressing social challenges. Additionally, it mentions professional tracks for corporate training and collaborations in various fields such as health and logistics.
The document discusses the importance of impact in health and social programs, specifically focusing on the history of maternity and child care clinics in Finland and their success in reducing maternal and infant mortality rates. It highlights the role of health sisters and midwives in providing essential prenatal care, achieving near-total coverage of pregnant women by 2015. Additionally, it mentions the development of a new population projection model informed by ongoing research and collaboration with policymakers in various Asian regions.
The document discusses happiness and how it relates to interaction with others. It argues that happiness is found through interaction rather than by pursuing it alone or viewing it as a possession. The challenge is developing linguistic awareness and concrete tools to change behavior and spread ideas about finding happiness in interaction. The project aims to participate in schools, workplaces and media to provide solutions.
This document outlines the process and activities for a challenge to develop solutions that create impact. It involves defining problems, ideating concepts, testing feasibility, and delivering solutions through converging and diverging phases. Participants are guided to define target users, partners, and scope of impact. The process focuses on understanding needs, benefits, resources, and touchpoints through user research. It aims to develop solutions in collaboration with partners and users to maximize real-world impact.
The document discusses the need for reforming curricula to create a "Generation Green" with a strong environmental focus. It notes that the global population is projected to reach 9 billion by 2050, putting increasing pressure on limited resources like clean drinking water, which over 1.8 billion people currently lack access to. Individual actions alone will not lead to sustainable solutions, so curricula are needed to facilitate a comprehensive understanding of environmental resource management and ensure clean resources for all through scalable, sustainable practices. The document calls readers to join this effort to educate the next "Generation Green" and help address worldwide resource challenges.
The Helsinki Sleep Factory is a virtual sleep society that aims to help adolescents understand and improve their sleep through a combination of chronobiology, motivational psychology, medicine, and problem-based learning approaches. It provides personalized sleep resources and solutions through an intelligent sleep diary, relaxation and mindfulness exercises, and a social community for sharing sleep-related content. The goal is to create accessible and effective interventions for conditions like delayed sleep phase, which can cause learning problems and school absenteeism if not addressed.
Biodiversity is being destroyed through many small incremental changes over time. This loss threatens our well-being and ability to adapt to climate change. To address this, the document proposes developing new mechanisms to neutralize negative impacts on biodiversity and turn losses into gains, such as through biodiversity offsets. Offsets involve compensating for biodiversity loss in one area by improving biodiversity elsewhere. This could create a market-based solution and new business opportunities, implementing the "polluter pays" principle. The proposal aims to incorporate offsets into legislation to balance development with conserving biodiversity in Finland.
This document proposes creating a "Citizen Mindscapes" project to analyze social media data from Suomi24 discussions in order to:
1) Detect early signs of social conflicts and problems in Finland;
2) Work against national divisions and support diversity; and
3) Strengthen skills in social big data analysis for research and business.
The project would involve analyzing the tens of millions of texts on Suomi24, which is used by 80% of Finns, to understand sentiments, consumption styles, hate speech, behaviors, and rhythms of everyday life and the economy.
This document discusses a challenge to connect and empower children in hospitals. It proposes an approach called Play-Learn-Heal that uses co-creation and human-centered design methods to develop social, material and digital solutions. These solutions aim to empower children, reduce stress, connect them to family and learning, and expand support networks during their hospital care and recovery. An interdisciplinary team of children, healthcare professionals, educators, designers and technologists will work together to create and test prototypes to positively impact children, hospitals, research and society.
This document discusses the need for a new approach to communicating information about climate change called "Climate Whirl". It notes that current information is fragmented across disciplines and sources, making it difficult for most people to understand climate change as a whole. Climate Whirl would be a science-based aggregator that combines climate and environmental information with health, social, and consumer insights using games, art, and citizen science to make climate change more understandable and relevant to everyday life. It would be developed by an interdisciplinary team with expertise in areas like environmental education, climate research, and public health.
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Guildford Flames Adam Long Helmet Design Challenge 2025Tom Hutchinson
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This is my submission for the 2025 Guildford Flames Goaltender Helmet Design Competition for Adam Long. This presentation goes over the different design elements I incorporated into my design of the helmet and justifies what was chosen. It also includes comprehensive views of the helmet from all three side which were to be edited in accordance to the brief.
Give Your Salon a Gorgeous Makeover with Interior Designs That Reflect Your P...SPL Interiors
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Your salon is more than just a business it's a reflection of your creativity, energy, and love for making others feel beautiful. At SPL Interiors, we understand that, and we pour our hearts into designing salon spaces that are as stunning as the services you offer. From elegant reception areas to calming treatment rooms, we carefully plan every detail to ensure your clients feel welcomed, pampered, and inspired the moment they step in. Let’s design a salon that feels like home for you and a dreamy escape for your clients.
Unleash Creativity with 3D T-Shirt Configurators_ A Game-Changer for Custom A...PrintXpand
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Design your perfect T-shirt in real time with our interactive 3D configurator. Customize colors, graphics, and fits—and see your changes instantly from every angle.