Wrist Type Blood Pressure Monitor KBP500
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The KBP500 is a wrist blood pressure monitor that measures blood pressure and pulse. It stores up to 60 readings with date and time stamps. It has a large LCD display and takes measurements through an oscillometric method. It is accurate for blood pressure within 3 mmHg and pulse within 5%. It runs on two AAA batteries and is suitable for daily home use to better manage one's blood pressure.
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Updates_in Head__Neck TNM staging- 9th edition.pptxDr. Maroti Wadewale
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The Union for International Cancer Control (UICC) and the American Joint Committee on Cancer (AJCC) collaborate closely to produce the globally recognized TNM Classification of Malignant Tumours. Therefore, when discussing the "9th edition of UICC head and neck staging," it's largely in alignment with the updates introduced by the AJCC's Version 9. The UICC's TNM Core Committee finalized the 9th edition of the TNM Classification, with publication anticipated in August 2025.
The key updates for head and neck cancers in the 9th edition (or Version 9) reflect an ongoing effort to improve prognostic accuracy and align staging with contemporary clinical understanding and treatment outcomes. Here are the significant changes, particularly those relevant to head and neck:
* Emphasis on Personalized Care and Prognostic Refinements: The 9th edition reflects a greater focus on personalized care, incorporating refinements that aim to better predict patient outcomes.
* Revised Criteria for Specific Head and Neck Cancers:
* Nasopharyngeal Carcinoma (NPC): This site has seen substantial revisions, as highlighted in the previous response on AJCC updates. Key changes include:
* More precise definition of T3 disease (unequivocal evidence of bone involvement).
* Introduction of advanced radiologic extranodal extension (ENE) as an N3 criterion. This acknowledges the prognostic impact of ENE seen on imaging.
* Subclassification of M1 disease into M1a (3 or fewer metastatic lesions) and M1b (more than 3 lesions) to better stratify prognosis in metastatic settings.
* Redefined Stage Groups for NPC, with T1-2N0-1 now often falling into Stage I, and Stage IV being exclusively for metastatic disease, further subdivided by the M1a/M1b categories.
* Salivary Gland Cancers: Revised criteria based on updated imaging and anatomical features are being incorporated.
* HPV-Related Oropharyngeal Cancers: New staging is introduced for HPV-associated oropharyngeal cancers to better reflect their distinct biological behavior and prognosis, which is generally more favorable than HPV-negative oropharyngeal cancers. This often involves specific considerations for nodal burden.
* Integration of Imaging and Anatomical Features: The updates are grounded in recent evidence, incorporating insights from advanced imaging techniques and a deeper understanding of anatomical spread.
* International Collaboration: These updates are the result of collaborative efforts between the AJCC and UICC, involving input from cancer registries, clinical outcomes data, and disease-specific experts worldwide. The goal is to provide a unified and globally applicable staging system.
* Dynamic Update Process: Similar to the AJCC's shift from "Editions" to "Versions" for specific sites, the UICC is also exploring more flexible ways to share future TNM updates.
In essence, the 9th edition of the UICC staging system for head and neck cancers, particularly in areas like NPC and HPVAD-SAFE: An Initiative to Build Understanding of ARIA and Skills Needed to Im...
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