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Blood.pdf

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This document contains 34 multiple choice questions related to pediatric hematology. The questions cover topics like causes of anemia, thalassemia, iron deficiency, hemolytic uremic syndrome, idiopathic thrombocytopenic purpura, vitamin K administration in newborns, and aplastic anemia. The correct answers are provided for each question.

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Made by B.A.H-39 Page 1 PAEDETRICS BCQs POOL of BLOOD by: B.A.H-39 Q.1 A 2 year old boy following an upper respiratory infection presents with pallor of rapid onset, weakness and fatigue. Jaundice is present on examination the direct antiglobulin test is positive. CBC shows leukocytosis, normal platelet count and there is reticulocytosis, urine shows increased urobilinogen and hemoglobinuria. The most like diagnosis is: A) Hereditary spherocytosis B) Hyper hemolytic crisis of sickle cell disease C) G6PD deficiency D) Hemolytic Uremic syndrome E) Autoimmune hemolytic anemia T Q2. Thrombocytopenia has been described in: A) SLE B) Leukemia C) Pernicious Anemia D) All of Above T E) A & C Q3. The least common drug which causes myelosupression is: A) Bleomycin T B) Procarbazine C) ARA-C D) DTIC E) Vinblastine Q4. Low HB A2 is observed in: A) Alpha thallesemia B) Hereditary persistence of HbF C) HbH disease D) Thalassemia E) All are correct T Q5. Megaloblastic Anemia is associated with: A) Goat’s Milk feeding B) Anti-epileptic Therapy C) Pica D) A & B T E) A& C Q6. An 18 months old Pakistani child has microcytic anemia, which dietary history findings best explains this? A) Pica T B) Lack of fresh vegetables in the diet C) Intake of inadequate amounts of fruit or juice. D) Intake of excessive amounts of vitamin C E) Intake of large amounts of unmodified cow’s milk Q7. In infancy and childhood which of the following infant is at greatest risk of Iron deficiency Anemia? A) A Premature infant T B) An infant with ABO incompatibility C) An infant with physiologic hyperbilirubinemia D) A post mature infant E) An Infant with polycythemia Q8. Testing reveals a microcytic hypochromic anemia along with normal serum iron. The most likely diagnosis is: A) Vitamin B12 B) Thalassemia T C) Hemosiderosis D) Iron deficiency Anemia E) Sickle Cell Disease Q9. The fanconi syndrome is characterized by which of the following? A) Azotemia, edema and hypertension B) Glycosuria, aminoaciduria, and phosphaturia T C) Hematuria, glycosuria, and proteinuria D) Hypoglycemia, glycosuria , hypoglycemia and glycinuria E) Uremia, phosphaturia and albuminuria Q10. Which of the following would be indication of splenectomy in 3 year old child? A) Platelet count below 10,000 mm 3 B) Gingival bleeding C) Persistence of thrombocytopenia for more than 1 month D) Persistence of thrombocytopenia for more than 1-2 year T E) Presence of splenomegaly and anemia Q11. Acute idiopathic thrombocytopenic purpura A) Child is usually sick B) is common in female C) Reports reveal neutropenia D) Rrespond to Steroids E) Bone marrow reveals decreased number of platelets Q12. Thalassemia minor A) Is usually present in parents of thalassemia major child B) Has normocytic, normochromic anemia in patients C) Hemoglobin A2 is raised T D) Responds to Iron therapy E) Children mostly belong to European area, Q13. A 20 month old child develops haemolytic anemia, anuria, azotemia and thrombocytopenia after a bout of febrile bloody diarrhoea. What is most likely diagnosis? A) Bacillary dysentery B) Amoebic dysentry C) Intussusception D) Hemolytic uremic syndrome T E) Henochscholen purpura Q14. A 2 year old child was on goat’s milk. Now presented with progressive pallor. Among the following which is the most likely cause of his anemia? A) Vitamin B12 deficiency B) Folic acid deficiency T C) X-linked D) Y-linked E) Multifactorial Q15. Transmission of Thalassemia is A) Autosomal dominant B) Autosomal recessive T C) X-Linked D) Y-Linked E) Multifactorial Q16. Commonest cause of microcytic hypochromic anemia is A) Thalassemia B) Lead Poisoning C) Iron deficiency Anemia T D) Folic acid deficiency E) B12 deficiency Q17. Iron deficiency is common in young children due to A) Rapid growth of body B) Breast feeding and early weaning C) Excessive use of cow’s milk D) Worm infection E) More use of tea T Q18. Ideal treatment of ITP in children is: A) Steroids T B) Antibiotics C) Wait and Watch D) Blood transfusion E) Symptomatic
Made by B.A.H-39 Page 2 PAEDETRICS BCQs POOL of BLOOD by: B.A.H-39 Q19. For Treatment of ITP steroids should be given for: A) One week B) Two weeks C) Three weeks D) Four weeks E) Until the platelet count returns to normal or minimum three weeks which area is earlier T Q20. Most common cause of ITP in children is: A) Preceding Skin Infectio B) Preceding Throat infection T C) Gastroenteritis D) Malaria E) Drugs Q21. Most common presentation of ITP in children is: A) Just with purpura and nothing else T B) Fever and purpura C) Bleeding from gums D) Hematuria E) Bleeding per rectum Q22. Most common type of anemia in Pakistani children: A) Iron deficiency T B) Aplastic Anemia C) Hypoplastic Anemia D) Hemolytic Anemia E) Hemorrhagic anemia Q23. Iron therapy should be continued in iron deficiency anemic children for: A) One month B) Three months C) Until HB returns to normal D) Six months E) One to two months after correction of anemia T Q24. Earliest sign of iron deficiency anemia in school going children is: A) Abdminal pain B) Lack of sleep C) Poor school performance D) Lack of concentration T E) Reduced Intelligence Q25. Iron deficiency Anemia is most commonly seen in children between the ages of: A) 0-6 months B) 6m-01 year C) 09 months-18 months D) 1-2 years E) 2-5 years Q26. Most common cause of iron deficiency anemia in young children is: A) Lack of iron in diet B) Breast Feeding C) Late weaning T D) Worm infestation E) Rectal polyp Q27. Most common cause of iron deficiency anemia in older children is: A) Lack of iron in diet T B) low calorie diet C) Excessive use of tea D) Lack of taking iron medication E) Piles Q28. Amount of blood to be given to children with severe anemia is: A) 10-20ml/kg B) 20 ml/kg T C) 25 ml/kg D) 30 ml/kg E) 15 ml/kg Q29. Every newborn baby should be given vitamin K1 : A) 1mg I/m at birth T B) 1 mg S/C at birth C) 1mg ¼ at birth D) 2mg I/m during 1 st 3 days E) 2mg I/m on day 1. Q30. Vitamin K is given routinely to newborn babies to A) Prevent hemorrhage disease of newborn B) Prevent hemolytic diseases of newborn C) Improve the clotting factors D) Overcome deficiency of vit K dependant clotting factors E) Treat hemorrhagic disease of newborn Q31.Hemorrhagic disease of newborn commonly present with: A) Bleeding from umbilicus T B) Petichie C) Brunsies D) Bleeding from gums E) Hematuria Q32. Commonest form of purpura seen in children is: A) Idiopathic thrombocytic purpura T B) Purpura with malaria C) Drug induced purpura D) Purpura associated with all E) Q33. Most common cause of aplastic anemia in children in Pakistan: A) Drug induced B) Idiopathic T C) Leukemia D) Infection E) Malaria Q34. Acquired aplastic anemia in Pakistan can best possibly be treated by: A) Bone marrow transplantation T B) Blood Transfusion C) Steroids D)Immunosuppressive drugs E)Treatment of Cause

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Blood.pdf

  • 1. Made by B.A.H-39 Page 1 PAEDETRICS BCQs POOL of BLOOD by: B.A.H-39 Q.1 A 2 year old boy following an upper respiratory infection presents with pallor of rapid onset, weakness and fatigue. Jaundice is present on examination the direct antiglobulin test is positive. CBC shows leukocytosis, normal platelet count and there is reticulocytosis, urine shows increased urobilinogen and hemoglobinuria. The most like diagnosis is: A) Hereditary spherocytosis B) Hyper hemolytic crisis of sickle cell disease C) G6PD deficiency D) Hemolytic Uremic syndrome E) Autoimmune hemolytic anemia T Q2. Thrombocytopenia has been described in: A) SLE B) Leukemia C) Pernicious Anemia D) All of Above T E) A & C Q3. The least common drug which causes myelosupression is: A) Bleomycin T B) Procarbazine C) ARA-C D) DTIC E) Vinblastine Q4. Low HB A2 is observed in: A) Alpha thallesemia B) Hereditary persistence of HbF C) HbH disease D) Thalassemia E) All are correct T Q5. Megaloblastic Anemia is associated with: A) Goat’s Milk feeding B) Anti-epileptic Therapy C) Pica D) A & B T E) A& C Q6. An 18 months old Pakistani child has microcytic anemia, which dietary history findings best explains this? A) Pica T B) Lack of fresh vegetables in the diet C) Intake of inadequate amounts of fruit or juice. D) Intake of excessive amounts of vitamin C E) Intake of large amounts of unmodified cow’s milk Q7. In infancy and childhood which of the following infant is at greatest risk of Iron deficiency Anemia? A) A Premature infant T B) An infant with ABO incompatibility C) An infant with physiologic hyperbilirubinemia D) A post mature infant E) An Infant with polycythemia Q8. Testing reveals a microcytic hypochromic anemia along with normal serum iron. The most likely diagnosis is: A) Vitamin B12 B) Thalassemia T C) Hemosiderosis D) Iron deficiency Anemia E) Sickle Cell Disease Q9. The fanconi syndrome is characterized by which of the following? A) Azotemia, edema and hypertension B) Glycosuria, aminoaciduria, and phosphaturia T C) Hematuria, glycosuria, and proteinuria D) Hypoglycemia, glycosuria , hypoglycemia and glycinuria E) Uremia, phosphaturia and albuminuria Q10. Which of the following would be indication of splenectomy in 3 year old child? A) Platelet count below 10,000 mm 3 B) Gingival bleeding C) Persistence of thrombocytopenia for more than 1 month D) Persistence of thrombocytopenia for more than 1-2 year T E) Presence of splenomegaly and anemia Q11. Acute idiopathic thrombocytopenic purpura A) Child is usually sick B) is common in female C) Reports reveal neutropenia D) Rrespond to Steroids E) Bone marrow reveals decreased number of platelets Q12. Thalassemia minor A) Is usually present in parents of thalassemia major child B) Has normocytic, normochromic anemia in patients C) Hemoglobin A2 is raised T D) Responds to Iron therapy E) Children mostly belong to European area, Q13. A 20 month old child develops haemolytic anemia, anuria, azotemia and thrombocytopenia after a bout of febrile bloody diarrhoea. What is most likely diagnosis? A) Bacillary dysentery B) Amoebic dysentry C) Intussusception D) Hemolytic uremic syndrome T E) Henochscholen purpura Q14. A 2 year old child was on goat’s milk. Now presented with progressive pallor. Among the following which is the most likely cause of his anemia? A) Vitamin B12 deficiency B) Folic acid deficiency T C) X-linked D) Y-linked E) Multifactorial Q15. Transmission of Thalassemia is A) Autosomal dominant B) Autosomal recessive T C) X-Linked D) Y-Linked E) Multifactorial Q16. Commonest cause of microcytic hypochromic anemia is A) Thalassemia B) Lead Poisoning C) Iron deficiency Anemia T D) Folic acid deficiency E) B12 deficiency Q17. Iron deficiency is common in young children due to A) Rapid growth of body B) Breast feeding and early weaning C) Excessive use of cow’s milk D) Worm infection E) More use of tea T Q18. Ideal treatment of ITP in children is: A) Steroids T B) Antibiotics C) Wait and Watch D) Blood transfusion E) Symptomatic
  • 2. Made by B.A.H-39 Page 2 PAEDETRICS BCQs POOL of BLOOD by: B.A.H-39 Q19. For Treatment of ITP steroids should be given for: A) One week B) Two weeks C) Three weeks D) Four weeks E) Until the platelet count returns to normal or minimum three weeks which area is earlier T Q20. Most common cause of ITP in children is: A) Preceding Skin Infectio B) Preceding Throat infection T C) Gastroenteritis D) Malaria E) Drugs Q21. Most common presentation of ITP in children is: A) Just with purpura and nothing else T B) Fever and purpura C) Bleeding from gums D) Hematuria E) Bleeding per rectum Q22. Most common type of anemia in Pakistani children: A) Iron deficiency T B) Aplastic Anemia C) Hypoplastic Anemia D) Hemolytic Anemia E) Hemorrhagic anemia Q23. Iron therapy should be continued in iron deficiency anemic children for: A) One month B) Three months C) Until HB returns to normal D) Six months E) One to two months after correction of anemia T Q24. Earliest sign of iron deficiency anemia in school going children is: A) Abdminal pain B) Lack of sleep C) Poor school performance D) Lack of concentration T E) Reduced Intelligence Q25. Iron deficiency Anemia is most commonly seen in children between the ages of: A) 0-6 months B) 6m-01 year C) 09 months-18 months D) 1-2 years E) 2-5 years Q26. Most common cause of iron deficiency anemia in young children is: A) Lack of iron in diet B) Breast Feeding C) Late weaning T D) Worm infestation E) Rectal polyp Q27. Most common cause of iron deficiency anemia in older children is: A) Lack of iron in diet T B) low calorie diet C) Excessive use of tea D) Lack of taking iron medication E) Piles Q28. Amount of blood to be given to children with severe anemia is: A) 10-20ml/kg B) 20 ml/kg T C) 25 ml/kg D) 30 ml/kg E) 15 ml/kg Q29. Every newborn baby should be given vitamin K1 : A) 1mg I/m at birth T B) 1 mg S/C at birth C) 1mg ¼ at birth D) 2mg I/m during 1 st 3 days E) 2mg I/m on day 1. Q30. Vitamin K is given routinely to newborn babies to A) Prevent hemorrhage disease of newborn B) Prevent hemolytic diseases of newborn C) Improve the clotting factors D) Overcome deficiency of vit K dependant clotting factors E) Treat hemorrhagic disease of newborn Q31.Hemorrhagic disease of newborn commonly present with: A) Bleeding from umbilicus T B) Petichie C) Brunsies D) Bleeding from gums E) Hematuria Q32. Commonest form of purpura seen in children is: A) Idiopathic thrombocytic purpura T B) Purpura with malaria C) Drug induced purpura D) Purpura associated with all E) Q33. Most common cause of aplastic anemia in children in Pakistan: A) Drug induced B) Idiopathic T C) Leukemia D) Infection E) Malaria Q34. Acquired aplastic anemia in Pakistan can best possibly be treated by: A) Bone marrow transplantation T B) Blood Transfusion C) Steroids D)Immunosuppressive drugs E)Treatment of Cause