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DR. KALYAN POLAVARAPU
M.S DNB (SURG.ONC)
FELLOWSHIP IN ONCOPLASTIC BREAST SURGERY
(U.K)
CONSULTANT - SURGICAL ONCOLOGIST
AMERICAN ONCOLOGY INSTITUTE
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Cancer is the uncontrolled growth of abnormal cells in the body.
Cancer develops when the bodys normal control mechanism stops
working.
Old cells do not die and instead grow out of control, forming
new, abnormal cells.
These extra cells may form a mass of tissue, called a tumor.
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Estimates indicate Indias reported cancer incidence in 2022 to be 19 to 20
lakhs, whereas real incidence is 1.5 to 3 times higher than the reported
cases.
High proportion of cases continue to be detected at late stages for major
cancer types in India.
The issue of high disease burden is compounded with late-stage detection
caused mainly due to lack of awareness and low penetration of screening
programs.
India has a poor cancer detection rate of 29%
Breast Lung & Cervical cancers diagnosed in
Stage 1  15 %
Stage 2  33%
which is significantly lesser than that in China, the UK and the US.
While at one hand incidence is rising, deaths due to cancer
has remained among the top 5 causes of deaths in India over
the last decade.
Estimates indicate that the total deaths due to cancer have
been ~8 to 9 lakh in 2020, causing the mortality to incidence
ratio for different cancer types in India being among the
poorest compared to global counterparts.
Based on reported cancer incidence and mortality across age groups and
years of potential productive life lost (YPPLL) due to the same, estimates
indicate that the economic burden in terms of GDP losses is in the
range of US$11B. (0.4% of national GDP) in 2020.
The same is projected to increase to US$36B to US$40B by 2030, driven by
a projected increase in mortality, improvement in life expectancy and increase
in GDP per capita.
cancer introduction  screening riskfactors.pptx
TOP 5 CANCERS IN INDIA
Rank Males Females Both sexes
1 Lip, oral cavity Breast Breast
2 Lung Cervix uteri Lip, Oral cavity
3 Stomach Ovary Cervix uteri
4 Colorectum Lip, oral cavity Lung
5 Oesophagus Colorectum Stomach
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A 3-year campaign for impact
2022-2024 Close The Care Gap
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2022: Realising the problem
2023: Uniting our voices and taking action
cancer introduction  screening riskfactors.pptx
cancer introduction  screening riskfactors.pptx
2024 : Together, we challenge those in power
CAUSES OF CANCER
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SYMPTOMS OF CANCER
cancer introduction  screening riskfactors.pptx
cancer introduction  screening riskfactors.pptx
cancer introduction  screening riskfactors.pptx
 Given the current state of rising cancer disease burden and sub-optimal quality of
outcomes, there is a significant need to understand the current challenges and tailor
make interventions across the different stages of disease management with a deep
focus on:
 A. Awareness and Prevention  Modifying exposure to risk factors that potentially
lead to cancer
 B. Detection and Diagnosis - Ensuring early detection and accurate staging of the
disease
 C. Treatment including Palliative care - Driving multidisciplinary approach to
treatment with focus on affordability, equitable access, quality of outcomes and
palliative car
 Awareness Knowledge: Awareness landscape in India is dominated by tobacco and
tobacco-related cancers. Knowledge of other common cancers such as cervical is low.
 Attitude: Few people in India seemed to be concerned about cancer compared to other
countries, implying a general attitude of indifference towards cancer.
 As per the UICC global survey, only 43% respondents in India indicated that they were
concerned or somewhat concerned about developing cancer in their lifetime compared
to a global average of 58%
 Practice: Uptake of screening for breast, cervical and oral cancer and HPV vaccination is
very low despite moderate levels of awareness.
AWARENESS
CANCER PREVENTION
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CANCER PREVENTION
 Primary Prevention
 Secondary Prevention
 At least 50% of cancers can be prevented
 Primary prevention - greatest potential - reduce burden of cancer
 Through healthy living, public policies & systemic changes
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 Primary prevention involves limiting exposure to carcinogenic risk factors.
 While there are several carcinogenic risk factors, modifiable risk factors such as tobacco, alcohol,
obesity, infectious and environmental factors are amenable to prevention.
 Enforcement of tobacco restrictions
 Enabling inclusion of HPV vaccination in the National Immunisation Program
 En cou ragin g h ealthy b eh aviors :
 Despite the proven benefits of early identification for
downstaging the disease as well as in achieving a reduction in
mortality and morbidity, screening penetration of key cancers
in India is very low.
 Across focus cancers being screened under the NPCDCS
programme, screening coverage is less than 5% of population
which is negligible when compared with global peers.
SCREENING
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ORAL CANCER
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Somewhere in the world
 A case of breast cancer is diagnosed
every 19 seconds
 A woman dies from breast cancer every 60
seconds
Over the next 25 years
 Another 42 million new cases are
expected worldwide
 Another 13 million people worldwide will
die from breast cancer
THE GLOBAL BREAST CANCER CRISIS
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BREAST CANCER SCREENING
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cancer introduction  screening riskfactors.pptx
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 Maintain a healthy weight
 Add exercise into your routine
 Limit alcohol intake
 Limit menopausal hormone use
 Breastfeed, if you can
Key Message  Make Healthy
Lifestyle Choices
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cancer introduction  screening riskfactors.pptx
cancer introduction  screening riskfactors.pptx
cancer introduction  screening riskfactors.pptx
cancer introduction  screening riskfactors.pptx
GOOD
HYGEINE
HEALTHY
LIFESTYLE
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HPV VACCINATION
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CANCER CONTROL FRAME WORK
cancer introduction  screening riskfactors.pptx
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cancer introduction screening riskfactors.pptx