Cell EXPLORERS: Cellular and molecular biology in the primary school classroom - Muriel Grenon and Shane McGuinness
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Muriel Grenon and Shane McGuinness, NUI Galway, presented Cell EXPLORERS - Cellular and molecular biology in the primary school classroom - at the Scientix course "STEM in primary school classrooms" at the Future Classroom Lab 25-29 June 2018.
Cell EXPLORERS: Cellular and molecular biology in the primary school classroom - Muriel Grenon and Shane McGuinness
- 1. Cell EXPLORERS Cellular and molecular biology in the primary school classroom Scientix Future Classroom Lab Scientix, 28 June 2018, Brussels M. Grenon, PhD & S. Mc Guinness, PhD, NUI Galway
- 2. Content of this workshop Introduction Inspiration Modern Biology Hands on Activities Little Cells - Cellular Biology Fantastic DNA molecular Biology Conclusion Activity suggestions Resources
- 3. Course objectives After this workshop you will be able to: Understand and explain the basic concepts of cellular and molecular biology in lay term Run hands-on activities on these topics in your classroom
- 4. Human Anatomy, McKingley & OLoughlin Anatomy Physiology Biochemistry Molecular Biology Cellular Biology Art work by Deviant Defaroe : http://www.deviantart.com/art/Biology-256551800 What do we study?Molecular basis of Life
- 5. Medical Biotechnology Why is it important? 1. Medicine of the future: Personalised: based on genomic information Will reflect what your cells can or cannot do New technology Faster drug development process Cell/Tissue specific Preventive (Test) Corrective (DNA) Regenerative (Organ, tissue) 2. Health & society implications: New profession New technological need New ethical impact
- 6. How does this workshop work? This is a teacher presentation pitched at your level You will do activities as the children would The presentations aimed at children, and resources, to run activities in the classroom are in the teacher section of our website www.cellexplorers.com: Free login Little Cells, Fantastic DNA as today Other resources
- 7. Little Cells An introduction to Cellular Biology 5-8 years old
- 8. Key concepts Essential functions of body carry out by organs All body parts are made of cells Cells are the smallest unit of life Cells going specific jobs have specific shapes Cells work together in our body
- 9. What are we made of? Resources: Little Cells Presentation The Body Games
- 10. Hi!
- 11. What are organs made of? 100 000 000 000 000 of Cells in our body Very small : 10 to 100 micrometers They do specific jobs: 200 Cell types They look different depending on the job they do Resources: Little Cells Presentation
- 12. How small are cells? You Cell Resources: Little Cells Presentation The Sizing Game
- 13. How small is a cell? Out of all these pictures which of these is the biggest and which is the smallest? Label them from 1 to 8: Number 1 is the biggest and number 8 is the smallest. LARGEST SMALLEST
- 14. Origin Fertilization of egg by sperm results in a zygote Zygote divides rapidly to form a compact ball of cells called a morula - totipotent Morula develops into embyro consisting of a small hollow cluster of cells called a blastocyst Two layers to the blastocyst Outer layer forms the placenta Inner cell mass is the source of human embryonic stem cells (hESCs) pluripotent From 1 cell type to 200 Self-renew indefinitely to produce more stem cells Create any cell type of the body: Differentiation Resources: (8years old+) Amazing cells Presentation
- 15. Adult stem cells example: Mesenchymal stem cells (MSCs) Multipotent stem cells found in bone marrow Resources: (8years old+) Card game by Curam
- 16. Around 200 different cell types!
- 18. Cells communicate to make the body work properly! Resources: Little Cells Presentation Playing Little Cells Game
- 20. Teachers Table + Buzzer! Brain and Nerves Heart and Heart cells Blood and Red Blood Cells 1 2 3
- 21. 8 - 13 years old Fantastic DNA An introduction to Molecular Biology
- 22. Parts of the cell Long narrated version: https://www.youtube.com/watch? v=FzcTgrxMzZk Youtube Video: The inner life of a cell 3 http://youtu.be/wJyUtbn0 O5Y Resources: Fantastic DNA Presentation
- 23. DNA is located in the cell nucleus 1. Contain cellular instruction 2. Instruction encoded in a 4 letters code 3. Species specific 4. Highly structured to allow its replication DNA from 1 cell is 1.8 m tall !! Resources: Fantastic DNA Presentation
- 24. DNA structure discoverers Resources: Fantastic DNA Presentation
- 25. DNA structure DNA rules A with T, C with G Resources: Fantastic DNA Presentation Model Building resources on Website
- 26. Reading the code In humans the code is written in 3,000,000,000 (= 3 billion) letters 98% the same! Resources: Fantastic DNA Presentation
- 27. Extracting DNA Basic step in DNA profiling, diagnostic and engineering experiment Extracted Amplified/sequenced Principle: Free up the DNA from: Membrane: mashing, soap Proteins: salt Render DNA insoluble to collect it: alcohol Resources: Fantastic DNA Presentation DIY DNA experiment
- 28. 1 x teaspoon of Salt 1 x Liquid Soap 2 x Plastic pint glass filled with water 2 x A plastic Sandwich bag 2 x Coffee filter paper 2 x Wooden stirrer 2 x Pairs of gloves 1 x Banana 2 x Small Plastic Cups Activity: Do it yourself DNA extraction Step 1: Collect what you need according to your checklist Step 2: Lets follow together the how to do it instruction (protocol) Step 3: Report on what you have done on your poster Checklist for a pair of children What you can do in the classroom: Variation on measure: Measuring volume, Weight Check importance of each component Resources: DIY DNA experiment
- 29. Poster report and presentation Resources: Poster template
- 30. Cell EXPLORERS resources Resources: in Teacher Zone page of www.cellexplorers.com Currently not on Scientix yet Let us know what you want to have translated (if any)
- 31. Other resources Biomedical Sciences with CURAM CURAM teacher in residence programme: Lesson Plan Kits developed by teachers in collaboration with Scientists Available to download: http://www.curamdevices.ie/curam/public- engagement/teachers-in-residence/
- 32. Conclusion Resources: in Teacher Zone page of www.cellexplorers.com Register online Contact us: cellexplorers@nuigalway.ie, Muriel.grenon@nuigalway.ie
- 33. Stay in touch! If you use the resources please let us know pictures summary link to class blog modifications Contact us: Shanemcguinness@nuigalway.ie, Muriel.grenon@nuigalway.ie
- 34. Thank you! Please fill out the evaluation form