This document describes a cell-free circulating DNA and RNA isolation kit that can isolate nucleic acids from small sample volumes of plasma, serum, urine, and follicular fluid. The kit offers scalable input volumes from 0.1 mL to 30 mL, provides rapid, robust and reliable isolation with excellent linearity, and produces inhibitor-free nucleic acids that are suitable for all downstream applications including fetal DNA screening, microarrays, genotyping, NGS, biomarker discovery, and methylation/epigenetics studies.
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CFC
1. Cell-Free Circulating
DNA & RNA
From Plasma/Serum, Urine, Follicular Fluid
Isolate from 0.1 mL to 30 mL
0.07
0.13
0.23
100 97
92
0
20
40
60
80
100
120
0.0
0.1
0.1
0.2
0.2
0.3
0.3
0.5mL 1mL 2mL
%ofLinearity
RelativeAmountof5SrRNA
Gene
Fetal DNA
Screening
Microarrays
Genotyping
NGS
Biomarker
Discovery
Methylation
Epigenetics
Scalable input volumes
Rapid, robust & reliable
Excellent linearity
Inhibitor-free
For all downstream applications
cfc-DNA cfc-RNA
0.E+00
2.E-08
4.E-08
6.E-08
8.E-08
1.E-07
1.E-07
1.E-07
Norgen Competitor Q Competitor A Competitor E
RelativeAmountofmiR-21in
Plasma
Norgen Biotek Corp.
www.norgenbiotek.com
