際際滷

際際滷Share a Scribd company logo
By/ Huda Eid AbdelWahab
2
Origin and sources
 Physico-chemical properties
 Applications and uses
3
Crustacean shells, insect exoskeleton
and some fungi =
mainly chitin.
4
Chitin
Chitosan
Deacetylation
(boiling 40-50%
NaOH)
5
硫(1 4) linked D-glucose units
硫(1 4) linked N-acetyl-D-glucos-
2-amine units
硫(1 4) linked D-glucos-2-amine
units
Degree of DeAcetylation > 60%
6
-OH: esterification, etherification,
oxidation,Elimination, protection reactions
-NH2: amidation, reduction, mono-, di- and
trialkylation (electrophile subsitution),
protection reactions
7
Complexation ability
 metal ions
 anionic polymers
 amino acids, proteins, DNA, cells
 dyes
 fats and cholesterol
8
SYNTHESIS OF SOME TEREPHTHALOYL THIOUREA
CROSS-LINKED CARBOXYMETHYL CHITOSAN HYDROGELS
9
SYNTHESIS OF SILICA-CHITOSAN HYBRIDS FOR
ANTIWETTING COATINGS
10
DEVELOPING A CHITOSAN SUPPORTED IMIDAZOLE
SCHIFF-BASE FOR HIGH-EFFICIENCY GENE DELIVERY
11
Characterization of a Conjugate between
Rose Bengal and Chitosan for Targeted
Antibiofilm and Tissue Stabilization
Effects as a Potential Treatment of
Infected Dentin
12
13
N-Phthaloylated Chitosan as
an
Essential Precursor for
Controlled
Chemical Modifications of
Chitosan
14
15
Synthesis And Characterization Of Chitosan Bi guanidine
Hydrochloride Under Microwave Irradiation
16
Carboxymethyl chitosan and
its
applications
17
18
19
20
21
SYNTHESIS ROUTE TO THE CHITOSAN DERIVATIVES OF
OCTADECYL-QUATERNIZED CARBOXYMETHYL CHITOSAN
22
SYNTHESIS OF PALMITOYL GLYCOL CHITOSAN
23
24
1-Water treatment
2-Paper
Removal of metal ions
Flocculant/coagulant (proteins, dyes,
aminoacids)
Filtration
Surface treatment
Photographic paper
Carbonless copy paper
Application
Examples
25
3-Medical
4- Cosmetics
Bandages, sponges
Artificial blood vessels
Blood cholesterol control
Tumor inhibition
Skin burns, artificial skin
Eye humor fluid
Contact lenses
Controlled release of drugs
Nanoparticles for drug delivery
Make-up powder
Nail polish
Mosturizers
26
5- Biotechnology
6- Agriculture
Enzyme/cell immobilization
Protein separation
Chromatography
Glucose electrode
Seed/leaf coating
Fertilizer
Controlled agrochemical
release
27
7- Food Removal of dyes and acids
Preservative
Color stabilization
Animal feed additive
As dietary food
Main properties used: antimicrobial ,
film forming, binding
capacity.
Chitosan
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Chitosan