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Pharma
CRO
A head-to-head comparison of
Pharma and CRO phase I-IV activities.
Rank Company Total R&D Development Phase I-IV
1 Novartis $9,727 $6,128 $4,351
2 Roche $9,656 $6,083 $4,319
3 Merck $7,123 $4,487 $3,186
4 P鍖zer $6,641 $4,184 $2,971
5 Quintiles $2,920
6 Sano鍖 $6,420 $4,045 $2,872
7 GSK $5,683 $3,580 $2,542
8 Eli Lilly $5,531 $3,485 $2,474
9 Bayer $4,313 $2,717 $1,929
10 AZ $4,281 $2,697 $1,915
11 Amgen $4,083 $2,572 $1,826
12 BMS $3,715 $2,340 $1,662
13 PAREXEL $1,532
14 Covance $1,494
15 Takeda $3,277 $2,065 $1,466
16 ICON $1,336
17 Otsuka $2,379 $1,499 $1,064
18 Gilead $2,167 $1,365 $969
19 Novo Nordisk $2,120 $1,336 $948
20 Astellas $1,998 $1,259 $894
Methodology
When you think about it, spending on phase I-IV services by pharma sponsors is
roughly equivalent to revenue generated by CROs. One companys expense is
another companys revenue. ISR wanted to see how the largest public CROs stacked
up to the largest pharma companies in terms of their phase I-IV activities. ISR used
the assumptions we generated in developing our 2014 CRO Market Size report to
develop a side-by-side comparison of phase I-IV activity between sponsors and
CROs. For sponsors: We took their annual R&D spending, multiplied it by 63% to get
their development spending, then multiplied that by 71% to get their phase I-IV
spending. For CROs: We took just their clinical development revenue (not commer-
cial, consulting, preclinical). Is this an exact match, no. However, directionally we 鍖nd
that of the 20 companies performing the most phase I-IV activities, at least four of
them are CROs and, if their 鍖nancials were publicly available, we could have easily
included PPD and perhaps PRA, inVentiv Health Clinical, and INC Research in the list.
www.ISRreports.com info@ISRreports.com
Clinical
development
activity in
perspective
(Annual $B USD)

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Clinical development activity in perspective: A head-to-head comparison of Pharma and CRO phase I-IV activities

  • 1. Pharma CRO A head-to-head comparison of Pharma and CRO phase I-IV activities. Rank Company Total R&D Development Phase I-IV 1 Novartis $9,727 $6,128 $4,351 2 Roche $9,656 $6,083 $4,319 3 Merck $7,123 $4,487 $3,186 4 P鍖zer $6,641 $4,184 $2,971 5 Quintiles $2,920 6 Sano鍖 $6,420 $4,045 $2,872 7 GSK $5,683 $3,580 $2,542 8 Eli Lilly $5,531 $3,485 $2,474 9 Bayer $4,313 $2,717 $1,929 10 AZ $4,281 $2,697 $1,915 11 Amgen $4,083 $2,572 $1,826 12 BMS $3,715 $2,340 $1,662 13 PAREXEL $1,532 14 Covance $1,494 15 Takeda $3,277 $2,065 $1,466 16 ICON $1,336 17 Otsuka $2,379 $1,499 $1,064 18 Gilead $2,167 $1,365 $969 19 Novo Nordisk $2,120 $1,336 $948 20 Astellas $1,998 $1,259 $894 Methodology When you think about it, spending on phase I-IV services by pharma sponsors is roughly equivalent to revenue generated by CROs. One companys expense is another companys revenue. ISR wanted to see how the largest public CROs stacked up to the largest pharma companies in terms of their phase I-IV activities. ISR used the assumptions we generated in developing our 2014 CRO Market Size report to develop a side-by-side comparison of phase I-IV activity between sponsors and CROs. For sponsors: We took their annual R&D spending, multiplied it by 63% to get their development spending, then multiplied that by 71% to get their phase I-IV spending. For CROs: We took just their clinical development revenue (not commer- cial, consulting, preclinical). Is this an exact match, no. However, directionally we 鍖nd that of the 20 companies performing the most phase I-IV activities, at least four of them are CROs and, if their 鍖nancials were publicly available, we could have easily included PPD and perhaps PRA, inVentiv Health Clinical, and INC Research in the list. www.ISRreports.com info@ISRreports.com Clinical development activity in perspective (Annual $B USD)