Combating the effects of pacnes
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This document summarizes how Propionibacterium acnes (P. acnes) promotes comedones and causes inflammatory responses in the skin. It discusses five ways P. acnes promotes comedones: through biofilms, the IGF pathway, aberrant integrin expression, production of free fatty acids, and oxidation of squalene. It also lists natural extracts and compounds that can target each of these mechanisms. Additionally, it outlines several inflammatory cytokines and receptors induced by P. acnes, and recommends natural extracts shown to inhibit each one. The document promotes learning more about these topics by visiting the provided website or contacting the listed email.
Combating the effects of pacnes
- 1. Combating the effects of p.Acnesp.Acnes
- 2. How does p.Acnes promote comedones? 1. Biofilms 2. IGF Pathway 3. Aberrant Integrin Expression3. Aberrant Integrin Expression 4. Production of FFA 5. Oxidation of Squalene
- 4. Biofilms
- 7. Production of FFA Bellamcanda Chinensis Root Extract TetracyclinesTetracyclines Erythromycin Isotretinoin Diet influences sebaceous synthesis
- 9. P. Acnes causes the following inflammatory responses: IL-12 IL-8 TLR2 TLR4 Lipase IL-1 IL-6 IL-17 TNF-a MMP-2 NLRP3
- 10. IL-12 Turmeric, Green Tea IL-8 Magnolia Bark Extract, Turmeric, Niacinamide, Green Tea, Zinc, Resveratrol.Niacinamide, Green Tea, Zinc, Resveratrol. TLR2 Zinc TLR4 Resveratrol.
- 11. Lipase Magnolia Bark Extract, Bellamcanda Chinensis Root Extract IL-1 Nettle Extract, Turmeric, Green Tea, Resveratrol, Vitamin C, rosemary Extract, Zinc IL-6 - Taraktgenos Kurzii Seed Oil,Nigella Sativa Seed Oil, Leptospermum Scoparium Branch/Leaf Oil and Magnolia Grandiflora Bark Extract, Zinc, Vitamin C
- 12. IL-17 Resveratrol, TNF-a Magnolia Bark Extract, Turmeric, Taraktgenos Kurzii Seed Oil,Nigella Sativa Seed Oil, Leptospermum Scoparium Branch/Leaf Oil and Magnolia Grandiflora BarkBranch/Leaf Oil and Magnolia Grandiflora Bark Extract, Zinc, Vitamin C, rosemary extract. MMP-2 Vitamin C, Resveratrol. NLRP3 Green Tea
- 13. If you would like to know more www.roccoco.com.auwww.roccoco.com.au Or jacine@roccoco.com.au
- 14. Next Webinar.. Monday 28th April AEST at 9am.