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A A F O B
AAFOB
                              Te c h n o l o g y




                                 TechTranfer

BMM
  biotecnolog鱈a
  microbiana
  marina

  Universidad de Valpara鱈so
                                 Office


                      Chile
AAFOB
                                                        Te c h n o l o g y




Marine natural product

Produced and obtained from a marine bacterium by a controled cost-effective
bioprocess

                               Physical         Food Industry

Surface active molecules


                               Biological       Aquaculture 90 % 1,4
                               million pof tons
The only way to meet the increasing demand for fish is through aquaculture
                                                    Daniel Cressey, Nature 458, 398-400 (2009
Biomass increases and pathogen apparitions
AAFOB
                                                 Te c h n o l o g y
Aquaculture challenges


    Economic loses                          Food safety

                     Pathogen outbreaks
         +             Green actions             +
                      Avoid antibiotics
                     New functional diets
AAFOB
                                                                          Te c h n o l o g y

       USERS: SALMON FARMS                                    CUSTOMER: FEED INDUSTRY




                                            Billions people
Million tons




       Fast growing economic activity 8,8
       % of annual growth rate

       60 million tonnes in 2010 with a
       value of U$ 119 billion

       Mayor producer: China with 60 %
Funcional Diets
AAFOB
                                                           Te c h n o l o g y

          QUORUM SENSING AND PATHOGENICITY




                                     VIRULENCE                   VIRULENCE
                                     ACTIVATED                   INHIBITED
Chemical Signal for Quorum Sensing
AAFOB                        Inhibitions by AAFOB is selective
                             without resistence generation

                             Quorum sensing is involved in fish
                             pathogens
AAFOB
                                               Te c h n o l o g y
COMPETITORS
                   ANTIBIOTICS      VACCINES           AAFOB

 Specificity                                            

 Resistance            X               X                  
 Production cost                      X                  
 Implementation cost                  X                  
 Food safety                                             
                       X
 Environment
                       X                                 


   CUSTOMER BENEFITS
                                 BIOMASS PRODUCTION
                                 FOOD SAFETY
AAFOB
       Te c h n o l o g y
AAFOB TECH TRANSFER
AAFOB
                                                             Te c h n o l o g y
                                           Funded by
Scienti鍖c validation   Chilean             Fondef D07I1061
and Patent             International PCT   Corfo Innova L4

Licences               Productive          Corfo Innova L4
                       Comercial
Trade Mark             INAPI

Spin off               Micro MBtk Biotk    Corfo Innova L4
                                           Fondef VIU
Investors seeking to   UE and EEUU         Corfo GoTo Market
implement production
and distribution


                                 OK

                                 Developing
AAFOB
                                           Te c h n o l o g y
Go To Market Barriers

                          Natural products
    Local Regulations    Toxicity assays (in vitro and LD50)
                          Field assay with AAFOB based diets


    Production           HC Industrial Fermentation is
                           required


    Distribution         For global market
AAFOB
                             Te c h n o l o g y

Enregy        Aquaculture

   Industry                 Biomedicine
Marine natural products can support the sustainable growth of an aquaculture safe for people and environmentally friendly




                                                                                    AAFOB
                                                                                   Te c h n o l o g y

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Corfogoto

  • 1. A A F O B
  • 2. AAFOB Te c h n o l o g y TechTranfer BMM biotecnolog鱈a microbiana marina Universidad de Valpara鱈so Office Chile
  • 3. AAFOB Te c h n o l o g y Marine natural product Produced and obtained from a marine bacterium by a controled cost-effective bioprocess Physical Food Industry Surface active molecules Biological Aquaculture 90 % 1,4 million pof tons
  • 4. The only way to meet the increasing demand for fish is through aquaculture Daniel Cressey, Nature 458, 398-400 (2009
  • 5. Biomass increases and pathogen apparitions
  • 6. AAFOB Te c h n o l o g y Aquaculture challenges Economic loses Food safety Pathogen outbreaks + Green actions + Avoid antibiotics New functional diets
  • 7. AAFOB Te c h n o l o g y USERS: SALMON FARMS CUSTOMER: FEED INDUSTRY Billions people Million tons Fast growing economic activity 8,8 % of annual growth rate 60 million tonnes in 2010 with a value of U$ 119 billion Mayor producer: China with 60 %
  • 9. AAFOB Te c h n o l o g y QUORUM SENSING AND PATHOGENICITY VIRULENCE VIRULENCE ACTIVATED INHIBITED Chemical Signal for Quorum Sensing AAFOB Inhibitions by AAFOB is selective without resistence generation Quorum sensing is involved in fish pathogens
  • 10. AAFOB Te c h n o l o g y COMPETITORS ANTIBIOTICS VACCINES AAFOB Specificity Resistance X X Production cost X Implementation cost X Food safety X Environment X CUSTOMER BENEFITS BIOMASS PRODUCTION FOOD SAFETY
  • 11. AAFOB Te c h n o l o g y AAFOB TECH TRANSFER
  • 12. AAFOB Te c h n o l o g y Funded by Scienti鍖c validation Chilean Fondef D07I1061 and Patent International PCT Corfo Innova L4 Licences Productive Corfo Innova L4 Comercial Trade Mark INAPI Spin off Micro MBtk Biotk Corfo Innova L4 Fondef VIU Investors seeking to UE and EEUU Corfo GoTo Market implement production and distribution OK Developing
  • 13. AAFOB Te c h n o l o g y Go To Market Barriers Natural products Local Regulations Toxicity assays (in vitro and LD50) Field assay with AAFOB based diets Production HC Industrial Fermentation is required Distribution For global market
  • 14. AAFOB Te c h n o l o g y Enregy Aquaculture Industry Biomedicine
  • 15. Marine natural products can support the sustainable growth of an aquaculture safe for people and environmentally friendly AAFOB Te c h n o l o g y