1. This document discusses the challenges of conducting interdisciplinary global change science to understand complex environmental issues. 2. It provides a brief history of global change research programs and notes the need for a new system of global environmental science to integrate natural and social sciences across disciplinary, environmental, and development issues. 3. The document recognizes that global change science must find ways to include diverse local knowledge and voices from around the world to truly understand global systems and humanity's role in environmental changes.