This study investigated the effects of bed height and duration of chest compressions on intrathoracic pressure during CPR. The researchers found that compressions performed with the bed at mid-thigh height generated significantly higher pressures than lower bed heights. Pressures declined significantly after 2 minutes, suggesting fatigue. The optimal bed height was found to be with the top of the bed level with the operator's knee, to have the patient's chest at mid-thigh level. Changing compressors every 2 minutes may improve effectiveness by reducing fatigue effects.