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Cv Dec 2011

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Alice Viana
Alice Viana

The document is a curriculum vitae for Alice Fialho Viana. It summarizes her education, including a BSc in Pharmacy from Universidade Federal do Rio Grande do Sul in 1998, an MSc in Pharmaceutical Sciences from the same institution in 2002, and a PhD in Celular and Molecular Biology from Université de Rouen in 2007. It also outlines her professional experience, positions held, and 13 academic publications.

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CURRICULUM VITAE 1. Family name: Fialho Viana 2. First names: Alice 3. Gender: Female 4. Date of Birth: 07/APR/1975 5. Nationality: Brazillian 6. Civil status: single 7. Permanent address: 447, Miguel Tostes ap 202. Porto Alegre/ RS – Brazil 90430-061 8. Tel/ Mobile/ Email : 00 55 51 3332 2749 00 55 51 9117 7004 alice_fialho@yahoo.fr 9. Academic Career/titles: BSc. Pharmacy. Universidade Federal do Rio Grande do Sul. 1998 MSc. Pharmaceutical Sciences. Universidade Federal do Rio Grande do Sul. 2002 PhD. Celular and Molecular Biology Université de Rouen / FR. 2007 10. Language skills: (Mark 1 to 5 for competence) Language Reading Speaking Writing Portuguese (mother 5 5 5 language) English 5 4 4 French 5 4 3 Spanish 5 3 2 11. Other skills: Computer literate: Microsoft Office, Adobe Acrobat Professional, Adobe Photoshop, Sigma- Stat, Sigma-Plot, Microcal Origin Curve Fitting, Graph-Pad Prism, Scientist. 12. Professional experience record : Date: January 2010– current Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul – Faculty of Pharmacy Position / Activities Post-doctoral fellow Investigate the pharmacological profile of molecules with potential antidepressant anti-nociceptive and anti-psychotic activities. Mentor graduate students (Master’s and Doctoral degree) Teach graduate courses of Molecular Pharmacology. Manage budget and write projects for Government funding programs and write
final reports. Date: July 2002 – March 2003 and August 2010 - current Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul Position / Activities Teacher - Pharmacognosy II th Teaching 4 year Pharmacy students about the Pharmacology of Natural Products Date: April 2007 – Dec 2009 Location Florianópolis/ Brazil Company Universidade Federal de Santa Catarina - Pharmacology Department Position / Activities Post-doctoral fellow Research antidepressant, analgesic and anti-Parkinson activities of plant extracts. Development of animal models for the study of Parkinson's disease and also signaling pathways that relate the stress with diseases such as cystitis, irritable bowel syndrome, and depression. Participation in the tests of acute and chronic toxicity in partnership with the Laboratorio Catarinense- Brasil. Participation in multidisciplinary research projects to put into service the Biological Laboratory of Pre-clinical inflammation Pharmacology, write the Standard Operational Procedures. Mentor graduate students (Master’s and Doctoral degree). Manage budget and write projects for Governmental funding programs and write final reports. Date: November 2005 - March 2006 Location Porto Alegre/ Brazil Company Sanifer Laboratories Position / Activities Trainee – Production and Quality sectors Participation in the production line, quality control and writing of Standard Operational Procedure Date: March– October 2002 Location Porto Alegre/ Brazil Company São Lucas Hospital, Pontifícia Universidade Católica do Rio Grande do Sul Position Coordinator of phase III clinical trials (Pfiezer and Abbott) Coordinator of clinical research projects and product development. Trial phase II: drug for urinary incontinence (Pfizer) Trial phase IV: drug for erectile dysfunction (Abbott). Responsible for preparation and mailing of samples, scheduling interviews with patients and writing reports. Date: March 1999 - December 1999
Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul - Pharmacognosy Laboratory Position / Activities Laboratory monitor Preparation of laboratory material and substances for practical classes to Pharmacy undergraduates students Date: September 1998 – November 1998 Location Enschede / Netherlands Company Universitie Twente Position / Activities Trainee on textil enzyme treatment Evaluation of the effect of cellulases (enzymes) on cloths. Project sponsored by textile and soap Industries in order to improve the quality of fabrics. Date: September 1996 – 1997 Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul - Biotecnology Laboratory Position / Activities Undergraduate trainee on mutagenicity and genotoxity of alkaloids Assessment of mutagenicity and genotoxicity of alkaloids from Brazilian flora, specially, harman and harmine, on Saccharomyces cereviseae strains. Date: July 1995 Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul - Genetics Laboratory Position / Activities Undergraduate trainee on citogenetic technics Learning techniques of cytogenetics for studing and caracterizin rodents cariotype 13. Academic production PATENT DEPOSIT: RATES SMK, von POSER G, VIANA AF, COSTENTIN J, DOREGO JC. Neuroactive plant extract, pharmaceutical composition comprising the same and process for its production. No. of patent applications: PCT/EP2010/051816 Feb, 12, 2010. 1) STEIN AC, VIANA AF, MÜLLER LG, NUNES JM, STOLZ ED, DO REGO JC, COSTENTIN J, VON POSER GL, RATES SMK . Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: A promising new molecular pattern for the development of antidepressant drugs. Behavioural Brain Research, v. 1, p. 1, 2011. 2) VIANA AF, MACIEL IS, DORNELLES FN, FIGUEIREDO CP, SIQUEIRA JM, CAMPOS MM, CALIXTO JB. Kinin B1 receptors mediate depression-like behavior response in stressed mice treated with systemic E. coli lipopolysaccharide. J Neuroinflammation. v. 7, p.98, 2010.
3) HAAS J, VIANA AF, HECKLER A, von POSER G, RATES SMK. 2010. The Antinociceptive Effect of a Benzopyran (HP1) Isolated from in Mice Hot-Plate Test is Blocked by Naloxone. Planta Medica. v. 76, p.1419 – 1423, 2010. 4) VIANA AF, MACIEL IS, MOTTA EM, LEAL PC, PIANOWSKI L, CAMPOS MM, CALIXTO JB Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on its Dopaminergic Effects. Evidence Based Complementary Alternative Medicine. Oct 8, 2009. 5) VIANA AF, RATES SMK, NAUDIN B, COSTENTIN J, DOREGO JC. Effects of acute or 3- day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels. Journal of Psychopharmacology (Oxford). , v.1, p.681 - 690, 2008. 6) Do Rego JC, VIANA AF, LE MAITRE E, DENIEL A, RATES SM, LEROUX-NICOLLET I, COSTENTIN J. Comparisons between anxiety tests for selection of anxious and non anxious mice. Behavioural Brain Research, v. 169, p. 2, n. 282-288, 2006 7) VIANA AF, DOREGO JC, MUNAR L, HECKLER AP, DALLACOSTA TC, von POSER G, COSTENTIN J, RATES SMK. Hypericum caprifoliatum (Guttiferae) Cham. & Schltdl.: a species native to South Brazil with antidepressant-like activity. Fundamental & Clinical Pharmacology, v.20, p.507 - 514, 2006. 8) VIANA AF, DOREGO JC, von POSER G, FERRAZ A, HECKLER AP, COSTENTIN J, RATES SMK The antidepressant like effect of Hypericum caprifoliatum Cham & Schlecht (Guttiferae) on forced swimming test results from an inhibition of neuronal monoamine uptake. Neuropharmacology, v. 49, n. 7, p. 1042-1052, 2005. 9) VIANA AF, HECKLER AP, FENNER R, RATES SMK. Antinociceptive activity of Hypericum caprifoliatum and Hypericum polyanthemum (Guttiferae). Brazilian Journal of Medical and Biological Research, v. 36, p. 631-634, 2003. 10) NEVES G, FENNER R, HECKLER AP, VIANA AF, TASSO L, MENEGATTI R, FRAGA CA, BARREIRO EJ, DALLA-COSTA T, RATES SMK. Dopaminergic profile of new heterocyclic N-phenylpiperazine derivatives. Brazilian Journal of Medical Biological Research, 36: 625- 629, 2003. 11) VIANA AF, ANDREAZZA RS, DALLAGNOL R, von POSER GL, RATES SMK. Hypericum perforatum: elements for the rational use. Revista da AFARGS, v. 9, 2002. 12) BOEIRA JM, VIANA AF, PICADA JN, HENRIQUES JA. Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae. Mutatant Research, v. 20, p. 39-48, 2002 13) GNERRE C, POSER GL , FERRAZ A, VIANA AF, TESTA B, RATES SMK. Monoamine oxidase inhibitory activity of some Hypericum species native to South Brazil. Journal of Pharmacy and Pharmacology, v. 53, p. 1273-1279, 2001. PROFESSIONAL REFERENCES João Batista Calixto calixto@farmaco.ufsc.br Stela Maris Kuze Rates ratessmk@farmacia.ufrgs.br Jean Claude do Rego jean-claude.dorego@univ-rouen.fr Jean Costentin jean.costentin@univ-rouen.fr

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Cv Dec 2011

  • 1. CURRICULUM VITAE 1. Family name: Fialho Viana 2. First names: Alice 3. Gender: Female 4. Date of Birth: 07/APR/1975 5. Nationality: Brazillian 6. Civil status: single 7. Permanent address: 447, Miguel Tostes ap 202. Porto Alegre/ RS – Brazil 90430-061 8. Tel/ Mobile/ Email : 00 55 51 3332 2749 00 55 51 9117 7004 alice_fialho@yahoo.fr 9. Academic Career/titles: BSc. Pharmacy. Universidade Federal do Rio Grande do Sul. 1998 MSc. Pharmaceutical Sciences. Universidade Federal do Rio Grande do Sul. 2002 PhD. Celular and Molecular Biology Université de Rouen / FR. 2007 10. Language skills: (Mark 1 to 5 for competence) Language Reading Speaking Writing Portuguese (mother 5 5 5 language) English 5 4 4 French 5 4 3 Spanish 5 3 2 11. Other skills: Computer literate: Microsoft Office, Adobe Acrobat Professional, Adobe Photoshop, Sigma- Stat, Sigma-Plot, Microcal Origin Curve Fitting, Graph-Pad Prism, Scientist. 12. Professional experience record : Date: January 2010– current Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul – Faculty of Pharmacy Position / Activities Post-doctoral fellow Investigate the pharmacological profile of molecules with potential antidepressant anti-nociceptive and anti-psychotic activities. Mentor graduate students (Master’s and Doctoral degree) Teach graduate courses of Molecular Pharmacology. Manage budget and write projects for Government funding programs and write
  • 2. final reports. Date: July 2002 – March 2003 and August 2010 - current Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul Position / Activities Teacher - Pharmacognosy II th Teaching 4 year Pharmacy students about the Pharmacology of Natural Products Date: April 2007 – Dec 2009 Location Florianópolis/ Brazil Company Universidade Federal de Santa Catarina - Pharmacology Department Position / Activities Post-doctoral fellow Research antidepressant, analgesic and anti-Parkinson activities of plant extracts. Development of animal models for the study of Parkinson's disease and also signaling pathways that relate the stress with diseases such as cystitis, irritable bowel syndrome, and depression. Participation in the tests of acute and chronic toxicity in partnership with the Laboratorio Catarinense- Brasil. Participation in multidisciplinary research projects to put into service the Biological Laboratory of Pre-clinical inflammation Pharmacology, write the Standard Operational Procedures. Mentor graduate students (Master’s and Doctoral degree). Manage budget and write projects for Governmental funding programs and write final reports. Date: November 2005 - March 2006 Location Porto Alegre/ Brazil Company Sanifer Laboratories Position / Activities Trainee – Production and Quality sectors Participation in the production line, quality control and writing of Standard Operational Procedure Date: March– October 2002 Location Porto Alegre/ Brazil Company São Lucas Hospital, Pontifícia Universidade Católica do Rio Grande do Sul Position Coordinator of phase III clinical trials (Pfiezer and Abbott) Coordinator of clinical research projects and product development. Trial phase II: drug for urinary incontinence (Pfizer) Trial phase IV: drug for erectile dysfunction (Abbott). Responsible for preparation and mailing of samples, scheduling interviews with patients and writing reports. Date: March 1999 - December 1999
  • 3. Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul - Pharmacognosy Laboratory Position / Activities Laboratory monitor Preparation of laboratory material and substances for practical classes to Pharmacy undergraduates students Date: September 1998 – November 1998 Location Enschede / Netherlands Company Universitie Twente Position / Activities Trainee on textil enzyme treatment Evaluation of the effect of cellulases (enzymes) on cloths. Project sponsored by textile and soap Industries in order to improve the quality of fabrics. Date: September 1996 – 1997 Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul - Biotecnology Laboratory Position / Activities Undergraduate trainee on mutagenicity and genotoxity of alkaloids Assessment of mutagenicity and genotoxicity of alkaloids from Brazilian flora, specially, harman and harmine, on Saccharomyces cereviseae strains. Date: July 1995 Location Porto Alegre/ Brazil Company Universidade Federal do Rio Grande do Sul - Genetics Laboratory Position / Activities Undergraduate trainee on citogenetic technics Learning techniques of cytogenetics for studing and caracterizin rodents cariotype 13. Academic production PATENT DEPOSIT: RATES SMK, von POSER G, VIANA AF, COSTENTIN J, DOREGO JC. Neuroactive plant extract, pharmaceutical composition comprising the same and process for its production. No. of patent applications: PCT/EP2010/051816 Feb, 12, 2010. 1) STEIN AC, VIANA AF, MÃœLLER LG, NUNES JM, STOLZ ED, DO REGO JC, COSTENTIN J, VON POSER GL, RATES SMK . Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: A promising new molecular pattern for the development of antidepressant drugs. Behavioural Brain Research, v. 1, p. 1, 2011. 2) VIANA AF, MACIEL IS, DORNELLES FN, FIGUEIREDO CP, SIQUEIRA JM, CAMPOS MM, CALIXTO JB. Kinin B1 receptors mediate depression-like behavior response in stressed mice treated with systemic E. coli lipopolysaccharide. J Neuroinflammation. v. 7, p.98, 2010.
  • 4. 3) HAAS J, VIANA AF, HECKLER A, von POSER G, RATES SMK. 2010. The Antinociceptive Effect of a Benzopyran (HP1) Isolated from in Mice Hot-Plate Test is Blocked by Naloxone. Planta Medica. v. 76, p.1419 – 1423, 2010. 4) VIANA AF, MACIEL IS, MOTTA EM, LEAL PC, PIANOWSKI L, CAMPOS MM, CALIXTO JB Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on its Dopaminergic Effects. Evidence Based Complementary Alternative Medicine. Oct 8, 2009. 5) VIANA AF, RATES SMK, NAUDIN B, COSTENTIN J, DOREGO JC. Effects of acute or 3- day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels. Journal of Psychopharmacology (Oxford). , v.1, p.681 - 690, 2008. 6) Do Rego JC, VIANA AF, LE MAITRE E, DENIEL A, RATES SM, LEROUX-NICOLLET I, COSTENTIN J. Comparisons between anxiety tests for selection of anxious and non anxious mice. Behavioural Brain Research, v. 169, p. 2, n. 282-288, 2006 7) VIANA AF, DOREGO JC, MUNAR L, HECKLER AP, DALLACOSTA TC, von POSER G, COSTENTIN J, RATES SMK. Hypericum caprifoliatum (Guttiferae) Cham. & Schltdl.: a species native to South Brazil with antidepressant-like activity. Fundamental & Clinical Pharmacology, v.20, p.507 - 514, 2006. 8) VIANA AF, DOREGO JC, von POSER G, FERRAZ A, HECKLER AP, COSTENTIN J, RATES SMK The antidepressant like effect of Hypericum caprifoliatum Cham & Schlecht (Guttiferae) on forced swimming test results from an inhibition of neuronal monoamine uptake. Neuropharmacology, v. 49, n. 7, p. 1042-1052, 2005. 9) VIANA AF, HECKLER AP, FENNER R, RATES SMK. Antinociceptive activity of Hypericum caprifoliatum and Hypericum polyanthemum (Guttiferae). Brazilian Journal of Medical and Biological Research, v. 36, p. 631-634, 2003. 10) NEVES G, FENNER R, HECKLER AP, VIANA AF, TASSO L, MENEGATTI R, FRAGA CA, BARREIRO EJ, DALLA-COSTA T, RATES SMK. Dopaminergic profile of new heterocyclic N-phenylpiperazine derivatives. Brazilian Journal of Medical Biological Research, 36: 625- 629, 2003. 11) VIANA AF, ANDREAZZA RS, DALLAGNOL R, von POSER GL, RATES SMK. Hypericum perforatum: elements for the rational use. Revista da AFARGS, v. 9, 2002. 12) BOEIRA JM, VIANA AF, PICADA JN, HENRIQUES JA. Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae. Mutatant Research, v. 20, p. 39-48, 2002 13) GNERRE C, POSER GL , FERRAZ A, VIANA AF, TESTA B, RATES SMK. Monoamine oxidase inhibitory activity of some Hypericum species native to South Brazil. Journal of Pharmacy and Pharmacology, v. 53, p. 1273-1279, 2001. PROFESSIONAL REFERENCES João Batista Calixto calixto@farmaco.ufsc.br Stela Maris Kuze Rates ratessmk@farmacia.ufrgs.br Jean Claude do Rego jean-claude.dorego@univ-rouen.fr Jean Costentin jean.costentin@univ-rouen.fr