4. Jaundice
• He also complained of yellowish discoloration of eyes
• Insidious in onset
• First noticed by the realtives in the sclera
• Gradually progressive
• Progressed to torso –palms and soles
• Not associated with clay colored stools
• Associated with pruritus
• Associated with high color urine
5. Pruritus
• Insidious in onset
• Gradually progressive
• Initiated in palms and soles then progressed to the torso
• Initially it was nocturnal later diurnal pruritus developed
• Associated with excoriation marks in shin and abdomen.
• Associated with loss of appetite and loss of weight
6. Fever
• Insidious in onset
• High grade max 103 F
• Chills and rigor
• Continuous in nature
• Associated with jaundice
• Associated with loss of appetite and loss of weight
7. Negative history
• No h/o CAM intake
• No h/o abdominal lump
• No h/o hematemesis/melena
• No history of HPB surgery.
8. Past history Personal histroy
• No h/o major illness in the past.
• No h/o diabetes mellitus
• No h/o hypertension
• No h/o major surgery in the
past.
• Non alcoholic, non smoker
• Mixed diet
• No h/o tobacco or drug abuse
9. GPE
• Average built and nourishment
• Conscious, oriented
• Icterus +
• No Pallor, Cyanosis, Clubbing, Lymphadenopathy or Edema
• Vitals
• BP 110/70 mmHg
• PR 88/min
• SpO2 99% on Room air
10. Systemic examination
• GIT
• PA soft
• Non tender
• Gall bladder not palpable
• No evidence of free fluid in
abdomen
• Bowel sounds +
• spleen was not palpable.
• CNS
• Conscious, alert, oriented to time,
place and person
• No focal deficit
• RS
• Normal vesicular breath sounds
bilateral lung fields.
11. Investigations
TESTS RESULTS
CBC 7.7/10800/2.53 lakhs
DLC N54;L28
Urea/Creatinine 25/0.87
Na/K 138/3.9
T.B/D.B 5.18/3.48
ALT/AST 20/33
ALP 774 U/L
T.P/Alb 7.3/4.38
Amylase 20
PT INR 9.8/0.84
CA 19.9 and CEA 106.1 IU/ml and 1.16 ng/ml
Iron profile Serum iron 24.8 / ferritin 480
13. MRCP 22/12/2023
• Obstruction in the biliary system at the porta hepatis
• ?Inflitrative disorder
• GB wall thickening
• ? Malignancy Hilar cholangio ca